Altered Cellular Metabolism Drives Trained Immunity

Yahya Sohrabi*, Rinesh Godfrey, Hannes M. Findeisen*

*Corresponding author for this work

Research output: Contribution to journalEditorialAcademicpeer-review

22 Citations (Web of Science)

Abstract

Exposing innate immune cells to an initial insult induces a long-term proinflammatory response due to metabolic and epigenetic alterations which encompass an emerging new concept called trained immunity. Recent studies provide novel insights into mechanisms centered on metabolic reprogramming which induce innate immune memory in hematopoietic stem cells and monocytes.
Original languageEnglish
Pages (from-to)602-605
Number of pages5
JournalTrends in Endocrinology and Metabolism
Volume29
Issue number9
DOIs
Publication statusPublished - 1 Sep 2018

Keywords

  • INDUCTION

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