Alcohol consumption in later life and reaching longevity: the Netherlands Cohort Study

Piet A. van den Brandt; Lloyd Brandts

doi:10.1093/ageing/afaa003

Alcohol consumption in later life and reaching longevity: the Netherlands Cohort Study

Piet A. van den Brandt^*, Lloyd Brandts

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: whether light-to-moderate alcohol intake is related to reduced mortality remains a subject of intense research and controversy. There are very few studies available on alcohol and reaching longevity.

Methods: we investigated the relationship of alcohol drinking characteristics with the probability to reach 90 years of age. Analyses were conducted using data from the Netherlands Cohort Study. Participants born in 1916-1917 (n = 7,807) completed a questionnaire in 1986 (age 68-70 years) and were followed up for vital status until the age of 90 years (2006-07). Multivariable Cox regression analyses with fixed follow-up time were based on 5,479 participants with complete data to calculate risk ratios (RRs) of reaching longevity (age 90 years).

Results: we found statistically significant positive associations between baseline alcohol intake and the probability of reaching 90 years in both men and women. Overall, the highest probability of reaching 90 was found in those consuming 5-

Conclusions: the highest probability of reaching 90 years was found for those drinking 5-

Original language	English
Pages (from-to)	395-402
Number of pages	8
Journal	Age and Ageing
Volume	49
Issue number	3
DOIs	https://doi.org/10.1093/ageing/afaa003
Publication status	Published - May 2020

Keywords

alcohol
longevity
aging
dose-response relationship
mortality
cohort studies
older people
SCALE PROSPECTIVE COHORT
BINGE DRINKING
RISK-FACTORS
ALL-CAUSE
SURVIVAL
CANCER
QUESTIONNAIRE
MORTALITY
DRINKERS
DIET

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10.1093/ageing/afaa003Licence: CC BY-NC

Cite this

@article{d1c24e3d3c4b47539a048051a715df4b,

title = "Alcohol consumption in later life and reaching longevity: the Netherlands Cohort Study",

abstract = "Background: whether light-to-moderate alcohol intake is related to reduced mortality remains a subject of intense research and controversy. There are very few studies available on alcohol and reaching longevity.Methods: we investigated the relationship of alcohol drinking characteristics with the probability to reach 90 years of age. Analyses were conducted using data from the Netherlands Cohort Study. Participants born in 1916-1917 (n = 7,807) completed a questionnaire in 1986 (age 68-70 years) and were followed up for vital status until the age of 90 years (2006-07). Multivariable Cox regression analyses with fixed follow-up time were based on 5,479 participants with complete data to calculate risk ratios (RRs) of reaching longevity (age 90 years).Results: we found statistically significant positive associations between baseline alcohol intake and the probability of reaching 90 years in both men and women. Overall, the highest probability of reaching 90 was found in those consuming 5-Conclusions: the highest probability of reaching 90 years was found for those drinking 5-",

keywords = "alcohol, longevity, aging, dose-response relationship, mortality, cohort studies, older people, SCALE PROSPECTIVE COHORT, BINGE DRINKING, RISK-FACTORS, ALL-CAUSE, SURVIVAL, CANCER, QUESTIONNAIRE, MORTALITY, DRINKERS, DIET",

author = "{van den Brandt}, {Piet A.} and Lloyd Brandts",

note = "Publisher Copyright: {\textcopyright} 2020 The Author(s). Published by Oxford University Press on behalf of the British Geriatrics Society.",

year = "2020",

month = may,

doi = "10.1093/ageing/afaa003",

language = "English",

volume = "49",

pages = "395--402",

journal = "Age and Ageing",

issn = "0002-0729",

publisher = "Oxford University Press",

number = "3",

}

TY - JOUR

T1 - Alcohol consumption in later life and reaching longevity

T2 - the Netherlands Cohort Study

AU - van den Brandt, Piet A.

AU - Brandts, Lloyd

PY - 2020/5

Y1 - 2020/5

N2 - Background: whether light-to-moderate alcohol intake is related to reduced mortality remains a subject of intense research and controversy. There are very few studies available on alcohol and reaching longevity.Methods: we investigated the relationship of alcohol drinking characteristics with the probability to reach 90 years of age. Analyses were conducted using data from the Netherlands Cohort Study. Participants born in 1916-1917 (n = 7,807) completed a questionnaire in 1986 (age 68-70 years) and were followed up for vital status until the age of 90 years (2006-07). Multivariable Cox regression analyses with fixed follow-up time were based on 5,479 participants with complete data to calculate risk ratios (RRs) of reaching longevity (age 90 years).Results: we found statistically significant positive associations between baseline alcohol intake and the probability of reaching 90 years in both men and women. Overall, the highest probability of reaching 90 was found in those consuming 5-Conclusions: the highest probability of reaching 90 years was found for those drinking 5-

AB - Background: whether light-to-moderate alcohol intake is related to reduced mortality remains a subject of intense research and controversy. There are very few studies available on alcohol and reaching longevity.Methods: we investigated the relationship of alcohol drinking characteristics with the probability to reach 90 years of age. Analyses were conducted using data from the Netherlands Cohort Study. Participants born in 1916-1917 (n = 7,807) completed a questionnaire in 1986 (age 68-70 years) and were followed up for vital status until the age of 90 years (2006-07). Multivariable Cox regression analyses with fixed follow-up time were based on 5,479 participants with complete data to calculate risk ratios (RRs) of reaching longevity (age 90 years).Results: we found statistically significant positive associations between baseline alcohol intake and the probability of reaching 90 years in both men and women. Overall, the highest probability of reaching 90 was found in those consuming 5-Conclusions: the highest probability of reaching 90 years was found for those drinking 5-

KW - alcohol

KW - longevity

KW - aging

KW - dose-response relationship

KW - mortality

KW - cohort studies

KW - older people

KW - SCALE PROSPECTIVE COHORT

KW - BINGE DRINKING

KW - RISK-FACTORS

KW - ALL-CAUSE

KW - SURVIVAL

KW - CANCER

KW - QUESTIONNAIRE

KW - MORTALITY

KW - DRINKERS

KW - DIET

U2 - 10.1093/ageing/afaa003

DO - 10.1093/ageing/afaa003

M3 - Article

C2 - 32037449

SN - 0002-0729

VL - 49

SP - 395

EP - 402

JO - Age and Ageing

JF - Age and Ageing

IS - 3

ER -