This dissertation research studies the role of the glycocalyx, a gel layer on the inside of all blood vessels in the heart. The glycocalyx turns out to behave as a thick non-stick layer that prevents damaging parts to stick to the wall and as an extra space for blood when more oxygen needs to be transported from the blood to the heart. Temporary adjustments of this layer appear to positively influence the blood and oxygen supply, but when this layer is damaged, that does not happen. Repair of a damaged glycocalyx could in the future be a possible therapy for patients suffering from chest pain.
|Qualification||Doctor of Philosophy|
|Award date||29 Oct 2010|
|Place of Publication||Maastricht|
|Publication status||Published - 1 Jan 2010|
- blood vessels