Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms

Roderick C. Slieker, Maarten van Iterson, Rene Luijk, Marian Beekman, Daria V. Zhernakova, Matthijs H. Moed, Hailiang Mei, Michiel van Galen, Patrick Deelen, Marc Jan Bonder, Alexandra Zhernakova, Andre G. Uitterlinden, Ettje F. Tigchelaar, Coen D. A. Stehouwer, Casper G. Schalkwijk, Carla J. H. van der Kallen, Albert Hofman, Diana van Heemst, Eco J. de Geus, Jenny van DongenJoris Deelen, Leonard H. van den Berg, Joyce van Meurs, Rick Jansen, Peter A. C. 't Hoen, Lude Franke, Cisca Wijmenga, Jan H. Veldink, Morris A. Swertz, Marleen M. J. van Greevenbroek, Cornelia M. van Duijn, Dorret I. Boomsma, P. Eline Slagboom, Bastiaan T. Heijmans*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

54 Citations (Web of Science)
Original languageEnglish
Article number191
JournalGenome Biology (Online)
Volume17
DOIs
Publication statusPublished - 22 Sep 2016

Keywords

  • DNA methylation
  • Ageing
  • 450k
  • DNA damage
  • Variability

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