Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

Graham P. Holloway; Andrew M. Holwerda; Paula M. Miotto; Marlou L. Dirks; Lex B. Verdijk; Luc J. C. van Loon

doi:10.1016/j.celrep.2018.02.069

Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

Graham P. Holloway^*, Andrew M. Holwerda, Paula M. Miotto, Marlou L. Dirks, Lex B. Verdijk, Luc J. C. van Loon

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	2837-2848
Number of pages	12
Journal	Cell Reports
Volume	22
Issue number	11
DOIs	https://doi.org/10.1016/j.celrep.2018.02.069
Publication status	Published - 13 Mar 2018

Keywords

ADENINE-NUCLEOTIDE TRANSLOCASE
OXIDATIVE STRESS
IN-VIVO
INSULIN-RESISTANCE
ELDERLY-MEN
PERMEABILITY TRANSITION
PROTEIN SUPPLEMENTATION
SUPEROXIDE-PRODUCTION
RESPIRATORY CONTROL
H2O2 EMISSION

Cite this

Holloway, G. P., Holwerda, A. M., Miotto, P. M., Dirks, M. L., Verdijk, L. B., & van Loon, L. J. C. (2018). Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle. Cell Reports, 22(11), 2837-2848. https://doi.org/10.1016/j.celrep.2018.02.069

@article{bb0d5350c3d2435e9383b87c99ce9397,

title = "Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle",

keywords = "ADENINE-NUCLEOTIDE TRANSLOCASE, OXIDATIVE STRESS, IN-VIVO, INSULIN-RESISTANCE, ELDERLY-MEN, PERMEABILITY TRANSITION, PROTEIN SUPPLEMENTATION, SUPEROXIDE-PRODUCTION, RESPIRATORY CONTROL, H2O2 EMISSION",

author = "Holloway, {Graham P.} and Holwerda, {Andrew M.} and Miotto, {Paula M.} and Dirks, {Marlou L.} and Verdijk, {Lex B.} and {van Loon}, {Luc J. C.}",

year = "2018",

month = mar

day = "13",

doi = "10.1016/j.celrep.2018.02.069",

language = "English",

volume = "22",

pages = "2837--2848",

journal = "Cell Reports",

issn = "2211-1247",

publisher = "Cell Press",

number = "11",

}

Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle. / Holloway, Graham P.; Holwerda, Andrew M.; Miotto, Paula M.; Dirks, Marlou L.; Verdijk, Lex B.; van Loon, Luc J. C.

In: Cell Reports, Vol. 22, No. 11, 13.03.2018, p. 2837-2848.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Age-Associated Impairments in Mitochondrial ADP Sensitivity Contribute to Redox Stress in Senescent Human Skeletal Muscle

AU - Holloway, Graham P.

AU - Holwerda, Andrew M.

AU - Miotto, Paula M.

AU - Dirks, Marlou L.

AU - Verdijk, Lex B.

AU - van Loon, Luc J. C.

PY - 2018/3/13

Y1 - 2018/3/13

KW - ADENINE-NUCLEOTIDE TRANSLOCASE

KW - OXIDATIVE STRESS

KW - IN-VIVO

KW - INSULIN-RESISTANCE

KW - ELDERLY-MEN

KW - PERMEABILITY TRANSITION

KW - PROTEIN SUPPLEMENTATION

KW - SUPEROXIDE-PRODUCTION

KW - RESPIRATORY CONTROL

KW - H2O2 EMISSION

U2 - 10.1016/j.celrep.2018.02.069

DO - 10.1016/j.celrep.2018.02.069

M3 - Article

VL - 22

SP - 2837

EP - 2848

JO - Cell Reports

JF - Cell Reports

SN - 2211-1247

IS - 11

ER -

Access to Document

10.1016/j.celrep.2018.02.069