Adipogenesis from bovine precursors

Frea Mehta, Ruud Theunissen, Mark J. Post*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Abstract

Cultured meat, or tissue engineered meat, is a promising alternative to conventional meat production. In order to realistically mimic the multiple tissue types found in beef, food-compatible methods for bovine fat tissue engineering must be developed. We present a protocol for the isolation of adipose tissue-derived preadipocytes and subsequent adipogenic differentiation through free fatty acid stimulation. Differentiating preadipocytes can be either grown in 2D culture conditions or seeded in 3D alginate scaffolds. Differentiation is visually confirmed through lipophilic staining.
Original languageEnglish
Title of host publicationMyogenesis
EditorsSissel Beate Rønning
PublisherHumana Press
Pages111-125
Number of pages15
Volume1889
ISBN (Electronic)978-1-4939-8897-6
ISBN (Print)978-1-4939-8896-9
DOIs
Publication statusPublished - 1 Jan 2019

Publication series

SeriesMethods in Molecular Biology
Volume1889
ISSN1064-3745

Keywords

  • Adipogenic differentiation
  • Adipose
  • Alginate
  • Bovine
  • Branched chain fatty acid
  • Cultured meat
  • Free fatty acid
  • Lipid
  • Monounsaturated fatty acid
  • Preadipocyte

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