Adherence to the medical regime in patients with heart failure

Stefano Muzzarelli*, Hanspeter Brunner-La Rocca, Otmar Pfister, Pietro Foglia, Giorgio Moschovitis, Giorgio Mombelli, Hans Stricker

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


Aims To assess adherence to medical treatment in patients with heart failure (HF) using a specific questionnaire and measurement of the serum concentration of digoxin. Methods and results Forty patients with symptomatic HF and a clinical indication for digoxin were included in this pilot study. The assessment of adherence to the medical regime was based on two different methods: (i) the CARDIA-Questionnaire and (ii) the measurement of serum digoxin concentration (SDC) at 1 and 6 months. All patients were placed on digoxin treatment (target SDC 0.6-0.8 ng/mL) at baseline. Poor adherence was defined if the patient self-reported taking
Original languageEnglish
Pages (from-to)389-396
JournalEuropean journal of heart failure
Issue number4
Publication statusPublished - Apr 2010


  • Heart failure
  • Adherence to the medical regime

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