Additive Manufacturing Using Melt Extruded Thermoplastics for Tissue Engineering

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Melt extrusion of thermoplastic materials is an important technique for fabricating tissue engineering scaffolds by additive manufacturing methods. Scaffold manufacturing is commonly achieved by one of the following extrusion-based techniques: fused deposition modelling (FDM), 3D-fiber deposition (3DF), and bioextrusion. FDM needs the input material to be strictly in the form of a filament, whereas 3DF and bioextrusion can be used to process input material in several forms, such as pellets or powder. This chapter outlines a common workflow for all these methods, going from the material to a scaffold, while highlighting the special requirements of particular methods. A few ways of characterizing the scaffolds are also briefly described.

Original languageEnglish
Title of host publicationComputer-Aided Tissue Engineering
Subtitle of host publicationMethods and Protocols
EditorsAlberto Rainer, Lorenzo Moroni
Number of pages25
ISBN (Electronic)978-1-0716-0611-7
ISBN (Print)978-1-0716-0610-0
Publication statusPublished - 2021

Publication series

SeriesMethods in Molecular Biology


  • Biocompatible Materials/chemical synthesis
  • Biodegradable Plastics/chemical synthesis
  • Humans
  • Manufactured Materials
  • Microtechnology/instrumentation
  • Polymers/chemical synthesis
  • Printing, Three-Dimensional/instrumentation
  • Temperature
  • Tissue Engineering/instrumentation
  • Tissue Scaffolds/chemistry
  • Viscosity

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