Additional evidence for the existence of a precursor molecule of the prothrombin complex in oral anticoagulation

  • J.J. Veltkamp
  • , H. Muis
  • , A.D. Muller
  • , H.C. Hemker
  • , E.A. Loeliger

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

By means of the PTC-inhibitor neutralizing test (12) a significant excess of PTC (factor IX)-like material over factor IX activity could be demonstrated in human coumarin plasma. This cross-reacting material is considered to be a precursor of one or all of the clotting factors of the prothrombin complex.
Original languageEnglish
Pages (from-to)312-315
Number of pages4
JournalThrombosis et diathesis haemorrhagica
Volume25
Issue number2
DOIs
Publication statusPublished - 30 Jun 1971
Externally publishedYes

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