ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury

Daniela Sommer, Inge Corstjens, Selien Sanchez, Dearbhaile Dooley, Stefanie Lemmens, Jana Van Broeckhoven, Jeroen Bogie, Tim Vanmierlo, Pia M. Vidal, Stefan Rose-John, Myriam Gou-Fabregas, Sven Hendrix*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)129-145
Number of pages17
JournalBrain Behavior and Immunity
Volume80
DOIs
Publication statusPublished - Aug 2019

Keywords

  • ADAM17
  • Inflammation
  • Macrophages
  • Microglia
  • Spinal cord injury
  • MAST-CELLS PROTECT
  • TNF-ALPHA
  • ALTERNATIVE ACTIVATION
  • INFLAMMATORY RESPONSE
  • CNS REMYELINATION
  • UP-REGULATION
  • REGENERATION
  • DISINTEGRIN
  • EXPRESSION

Cite this

Sommer, D., Corstjens, I., Sanchez, S., Dooley, D., Lemmens, S., Van Broeckhoven, J., Bogie, J., Vanmierlo, T., Vidal, P. M., Rose-John, S., Gou-Fabregas, M., & Hendrix, S. (2019). ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. Brain Behavior and Immunity, 80, 129-145. https://doi.org/10.1016/j.bbi.2019.02.032