ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury

Daniela Sommer; Inge Corstjens; Selien Sanchez; Dearbhaile Dooley; Stefanie Lemmens; Jana Van Broeckhoven; Jeroen Bogie; Tim Vanmierlo; Pia M. Vidal; Stefan Rose-John; Myriam Gou-Fabregas; Sven Hendrix

doi:10.1016/j.bbi.2019.02.032

ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury

Daniela Sommer, Inge Corstjens, Selien Sanchez, Dearbhaile Dooley, Stefanie Lemmens, Jana Van Broeckhoven, Jeroen Bogie, Tim Vanmierlo, Pia M. Vidal, Stefan Rose-John, Myriam Gou-Fabregas, Sven Hendrix^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	129-145
Number of pages	17
Journal	Brain Behavior and Immunity
Volume	80
DOIs	https://doi.org/10.1016/j.bbi.2019.02.032
Publication status	Published - Aug 2019

Keywords

ADAM17
Inflammation
Macrophages
Microglia
Spinal cord injury
MAST-CELLS PROTECT
TNF-ALPHA
ALTERNATIVE ACTIVATION
INFLAMMATORY RESPONSE
CNS REMYELINATION
UP-REGULATION
REGENERATION
DISINTEGRIN
EXPRESSION

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10.1016/j.bbi.2019.02.032

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Sommer, D., Corstjens, I., Sanchez, S., Dooley, D., Lemmens, S., Van Broeckhoven, J., Bogie, J., Vanmierlo, T., Vidal, P. M., Rose-John, S., Gou-Fabregas, M., & Hendrix, S. (2019). ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. Brain Behavior and Immunity, 80, 129-145. https://doi.org/10.1016/j.bbi.2019.02.032

Sommer, Daniela ; Corstjens, Inge ; Sanchez, Selien ; Dooley, Dearbhaile ; Lemmens, Stefanie ; Van Broeckhoven, Jana ; Bogie, Jeroen ; Vanmierlo, Tim ; Vidal, Pia M. ; Rose-John, Stefan ; Gou-Fabregas, Myriam ; Hendrix, Sven. / ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. In: Brain Behavior and Immunity. 2019 ; Vol. 80. pp. 129-145.

@article{4fbf6938bf9749ef9951a0193d5118c4,

title = "ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury",

keywords = "ADAM17, Inflammation, Macrophages, Microglia, Spinal cord injury, MAST-CELLS PROTECT, TNF-ALPHA, ALTERNATIVE ACTIVATION, INFLAMMATORY RESPONSE, CNS REMYELINATION, UP-REGULATION, REGENERATION, DISINTEGRIN, EXPRESSION",

author = "Daniela Sommer and Inge Corstjens and Selien Sanchez and Dearbhaile Dooley and Stefanie Lemmens and {Van Broeckhoven}, Jana and Jeroen Bogie and Tim Vanmierlo and Vidal, {Pia M.} and Stefan Rose-John and Myriam Gou-Fabregas and Sven Hendrix",

year = "2019",

month = aug,

doi = "10.1016/j.bbi.2019.02.032",

language = "English",

volume = "80",

pages = "129--145",

journal = "Brain Behavior and Immunity",

issn = "0889-1591",

publisher = "Elsevier Science",

}

Sommer, D, Corstjens, I, Sanchez, S, Dooley, D, Lemmens, S, Van Broeckhoven, J, Bogie, J, Vanmierlo, T, Vidal, PM, Rose-John, S, Gou-Fabregas, M & Hendrix, S 2019, 'ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury', Brain Behavior and Immunity, vol. 80, pp. 129-145. https://doi.org/10.1016/j.bbi.2019.02.032

ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury. / Sommer, Daniela; Corstjens, Inge; Sanchez, Selien; Dooley, Dearbhaile; Lemmens, Stefanie; Van Broeckhoven, Jana; Bogie, Jeroen; Vanmierlo, Tim; Vidal, Pia M.; Rose-John, Stefan; Gou-Fabregas, Myriam; Hendrix, Sven.

In: Brain Behavior and Immunity, Vol. 80, 08.2019, p. 129-145.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury

AU - Sommer, Daniela

AU - Corstjens, Inge

AU - Sanchez, Selien

AU - Dooley, Dearbhaile

AU - Lemmens, Stefanie

AU - Van Broeckhoven, Jana

AU - Bogie, Jeroen

AU - Vanmierlo, Tim

AU - Vidal, Pia M.

AU - Rose-John, Stefan

AU - Gou-Fabregas, Myriam

AU - Hendrix, Sven

PY - 2019/8

Y1 - 2019/8

KW - ADAM17

KW - Inflammation

KW - Macrophages

KW - Microglia

KW - Spinal cord injury

KW - MAST-CELLS PROTECT

KW - TNF-ALPHA

KW - ALTERNATIVE ACTIVATION

KW - INFLAMMATORY RESPONSE

KW - CNS REMYELINATION

KW - UP-REGULATION

KW - REGENERATION

KW - DISINTEGRIN

KW - EXPRESSION

U2 - 10.1016/j.bbi.2019.02.032

DO - 10.1016/j.bbi.2019.02.032

M3 - Article

VL - 80

SP - 129

EP - 145

JO - Brain Behavior and Immunity

JF - Brain Behavior and Immunity

SN - 0889-1591

ER -