Acute pancreatitis

Lotte Boxhoorn; Rogier P. Voermans; Stefan A. Bouwense; Marco J. Bruno; Robert C. Verdonk; Marja A. Boermeester; Hjalmar C. van Santvoort; Marc G. Besselink

doi:10.1016/S0140-6736(20)31310-6

Acute pancreatitis

Lotte Boxhoorn, Rogier P. Voermans, Stefan A. Bouwense, Marco J. Bruno, Robert C. Verdonk, Marja A. Boermeester, Hjalmar C. van Santvoort, Marc G. Besselink^*

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Acute pancreatitis is an unpredictable and potentially lethal disease. The prognosis mainly depends on the development of organ failure and secondary infection of pancreatic or peripancreatic necrosis. In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach. Despite improvements in treatment and critical care, severe acute pancreatitis is still associated with high mortality rates. In this Seminar, we outline the latest evidence on diagnostic and therapeutic strategies for acute pancreatitis.

Original language	English
Pages (from-to)	726-734
Number of pages	9
Journal	Lancet
Volume	396
Issue number	10252
DOIs	https://doi.org/10.1016/S0140-6736(20)31310-6
Publication status	Published - 5 Sept 2020

Keywords

ALCOHOL-ASSOCIATED PANCREATITIS
STEP-UP APPROACH
INFECTED NECROTIZING PANCREATITIS
MILD GALLSTONE PANCREATITIS
RANDOMIZED CONTROLLED-TRIAL
LACTATED RINGERS SOLUTION
PERSISTENT ORGAN FAILURE
DUAL-MODALITY DRAINAGE
FLUID COLLECTIONS
EXOCRINE INSUFFICIENCY

Access to Document

10.1016/S0140-6736(20)31310-6

Cite this

@article{7b142a85fc614592808e285237b2fec5,

title = "Acute pancreatitis",

abstract = "Acute pancreatitis is an unpredictable and potentially lethal disease. The prognosis mainly depends on the development of organ failure and secondary infection of pancreatic or peripancreatic necrosis. In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach. Despite improvements in treatment and critical care, severe acute pancreatitis is still associated with high mortality rates. In this Seminar, we outline the latest evidence on diagnostic and therapeutic strategies for acute pancreatitis.",

keywords = "ALCOHOL-ASSOCIATED PANCREATITIS, STEP-UP APPROACH, INFECTED NECROTIZING PANCREATITIS, MILD GALLSTONE PANCREATITIS, RANDOMIZED CONTROLLED-TRIAL, LACTATED RINGERS SOLUTION, PERSISTENT ORGAN FAILURE, DUAL-MODALITY DRAINAGE, FLUID COLLECTIONS, EXOCRINE INSUFFICIENCY",

author = "Lotte Boxhoorn and Voermans, {Rogier P.} and Bouwense, {Stefan A.} and Bruno, {Marco J.} and Verdonk, {Robert C.} and Boermeester, {Marja A.} and {van Santvoort}, {Hjalmar C.} and Besselink, {Marc G.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2020",

month = sep,

day = "5",

doi = "10.1016/S0140-6736(20)31310-6",

language = "English",

volume = "396",

pages = "726--734",

journal = "Lancet",

issn = "0140-6736",

publisher = "Elsevier Science",

number = "10252",

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TY - JOUR

T1 - Acute pancreatitis

AU - Boxhoorn, Lotte

AU - Voermans, Rogier P.

AU - Bouwense, Stefan A.

AU - Bruno, Marco J.

AU - Verdonk, Robert C.

AU - Boermeester, Marja A.

AU - van Santvoort, Hjalmar C.

AU - Besselink, Marc G.

PY - 2020/9/5

Y1 - 2020/9/5

N2 - Acute pancreatitis is an unpredictable and potentially lethal disease. The prognosis mainly depends on the development of organ failure and secondary infection of pancreatic or peripancreatic necrosis. In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach. Despite improvements in treatment and critical care, severe acute pancreatitis is still associated with high mortality rates. In this Seminar, we outline the latest evidence on diagnostic and therapeutic strategies for acute pancreatitis.

AB - Acute pancreatitis is an unpredictable and potentially lethal disease. The prognosis mainly depends on the development of organ failure and secondary infection of pancreatic or peripancreatic necrosis. In the past 10 years, treatment of acute pancreatitis has moved towards a multidisciplinary, tailored, and minimally invasive approach. Despite improvements in treatment and critical care, severe acute pancreatitis is still associated with high mortality rates. In this Seminar, we outline the latest evidence on diagnostic and therapeutic strategies for acute pancreatitis.

KW - ALCOHOL-ASSOCIATED PANCREATITIS

KW - STEP-UP APPROACH

KW - INFECTED NECROTIZING PANCREATITIS

KW - MILD GALLSTONE PANCREATITIS

KW - RANDOMIZED CONTROLLED-TRIAL

KW - LACTATED RINGERS SOLUTION

KW - PERSISTENT ORGAN FAILURE

KW - DUAL-MODALITY DRAINAGE

KW - FLUID COLLECTIONS

KW - EXOCRINE INSUFFICIENCY

U2 - 10.1016/S0140-6736(20)31310-6

DO - 10.1016/S0140-6736(20)31310-6

M3 - (Systematic) Review article

SN - 0140-6736

VL - 396

SP - 726

EP - 734

JO - Lancet

JF - Lancet

IS - 10252

ER -