@inproceedings{8c9cac6f8e464f469a2036a091e17693,
title = "Acute Changes in P-Wave Morphology by Pulmonary Vein Isolation in Atrial Fibrillation Patients",
abstract = "Pulmonary vein (PV) plays an important role in atrial fibrillation (AF) initiation, progression, and stability. Successful PV isolation (PVI), either by radiofrequency catheter or Cryoballoon ablation, may terminate AF and prevent its recurrence. Whereas, incomplete PV isolation or reconnection of isolated PVs underlies mechanisms of AF recurrence. Hence, defining parameters able to predict a successful PVI and detect reconnections can assist clinicians in treatment of AF patients. Here, we developed a highly detailed human atrial model to simulate PVI and its acute effect on the P-wave morphology. Afterwards, the simulation results were compared and validated by recorded ECGs from patients before and after PVI procedure. In both simulation data and clinical recordings, we observed morphological changes in P-wave after PVI. More importantly our simulation helped us to find electrode positions, in which the differences in P-wave morphology before and after PVI were more pronounced.",
keywords = "BIOPHYSICAL MODEL, ABLATION, INSIGHTS, CATHETER",
author = "A. Gharaviri and M. Zink and M. Potse and S. Pezzuto and S. Zeemering and R. Krause and A. Auricchio and U. Schotten",
year = "2018",
month = sep,
doi = "10.22489/CinC.2018.034",
language = "English",
isbn = "9781728109589",
volume = "45",
series = "Computing in Cardiology Conference",
publisher = "IEEE",
booktitle = "Computing in Cardiology Conference, CinC 2018",
address = "United States",
note = "45th Computing in Cardiology Conference (CinC) ; Conference date: 23-09-2018 Through 26-09-2018",
}