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Activation of the NLRP3 inflammasome in microglia: the role of ceramide
Hannah Scheiblich
, Anna Schlütter
, Douglas T. Golenbock
, Eicke Latz
,
Pilar Martinez-Martinez
, Michael T. Heneka
*
*
Corresponding author for this work
MHeNs - Neuroscience
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Neuroscience
Caspase 1
20%
Ceramide
100%
Cycloserine
10%
Cytokine
10%
Enzymes
10%
Fingolimod
20%
Inflammasome
100%
Interleukin 1
70%
Microglia
100%
Neurodegenerative Disorder
10%
NOD-like Receptor
100%
Palmitic Acid
20%
Programmed Cell Death
10%
Proinflammatory Cytokine
10%
Pyrin Domain
100%
Receptor Agonists
10%
Serine Palmitoyltransferase
20%
Sphingosine-1-Phosphate Receptor
10%
Transferase Inhibitor
10%
Immunology and Microbiology
Agonist
10%
Caspase 1
20%
Cytokine
10%
Fingolimod
20%
Immune Response
10%
Inflammasome
100%
Inflammation
10%
Interleukin 1
70%
Microglia
100%
NOD-like Receptor
100%
Programmed Cell Death
10%
Proinflammatory Cytokine
10%
Pyrin Domain
100%
Secretion (Process)
30%
Serine
20%
Wild Type
20%
INIS
apoptosis
16%
applications
16%
cytokines
33%
enzymes
16%
inflammation
33%
inhibition
16%
injuries
16%
knock-out reactions
16%
levels
33%
modulation
16%
nervous system diseases
16%
phosphates
16%
proteins
33%
receptors
100%
secretion
50%
serine
33%
sodium
16%
synthesis
16%
transferases
33%
transport
16%
Pharmacology, Toxicology and Pharmaceutical Science
Serine Palmitoyltransferase
22%
Transferase Inhibitor
11%
Keyphrases
Primary Microglia
12%