Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair

Q. Shi, L. Maas, C. Veith, F. J. Van Schooten, R. W. Godschalk*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2425-2441
Number of pages17
JournalArchives of Toxicology
Volume91
Issue number6
DOIs
Publication statusPublished - Jun 2017

Keywords

  • Acidic pH
  • Benzo[a]pyrene
  • Cytochrome P450 (CYP1A1)
  • DNA damage
  • NER
  • NUCLEOTIDE EXCISION-REPAIR
  • OXIDATIVE STRESS
  • COMET ASSAY
  • EPITHELIAL-CELLS
  • INTRACELLULAR PH
  • ADDUCT FORMATION
  • CULTURED-CELLS
  • II CELLS
  • HYPOXIA
  • EXPRESSION

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