Targeting Three Brain Regions (Bilateral SMA, Left and Right DLPFC) Sequentially in One Session Using Combined Repetitive Transcranial Magnetic Stimulation and Intermittent Theta-burst Stimulation in Treatment-refractory Obsessive-compulsive Disorder: A Case Report

Po-Han Chou, Alexander T Sack, Kuan-Pin Su*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been widely used as a therapy for refractory obsessive-compulsive disorder (OCD). However, it remains unclear which exact target and stimulation sequence of rTMS is most effective for OCD. Here, we report the case of an 18-year-old female with treatment-refractory OCD whose symptoms markedly improved after combined rTMS and intermittent theta-burst stimulation over the bilateral dorsolateral prefrontal cortex and supplementary motor area. Our report indicates that combining treatment sequences that stimulate different brain regions sequentially is feasible and may clinically benefit patients suffering from OCD.

Original languageEnglish
Pages (from-to)773-776
Number of pages4
JournalClinical Psychopharmacology and Neuroscience
Volume20
Issue number4
DOIs
Publication statusPublished - 30 Nov 2022

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