A universal membrane-centric mechanotransduction mechanism for vibrationally stimulated cells

Lizebona August Ambattu; Lorenzo Moroni; Leslie Y. Yeo

doi:10.1038/s44222-026-00420-y

A universal membrane-centric mechanotransduction mechanism for vibrationally stimulated cells

Lizebona August Ambattu
, Lorenzo Moroni
, Leslie Y. Yeo^*

^*Corresponding author for this work

Research output: Contribution to journal › Editorial › Academic › peer-review

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Abstract

Cells can respond to vibrational frequencies beyond physiological frequency ranges, including those in the ultrasonic domain. Independent, standardized experiments that probe mechanotransduction across frequencies and vibration modalities could clarify the underlying mechanisms that enable this broadband responsiveness.

Original language	English
Pages (from-to)	394-395
Number of pages	2
Journal	Nature reviews bioengineering
Volume	4
Issue number	5
Early online date	1 Feb 2026
DOIs	https://doi.org/10.1038/s44222-026-00420-y
Publication status	Published - May 2026

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title = "A universal membrane-centric mechanotransduction mechanism for vibrationally stimulated cells",

abstract = "Cells can respond to vibrational frequencies beyond physiological frequency ranges, including those in the ultrasonic domain. Independent, standardized experiments that probe mechanotransduction across frequencies and vibration modalities could clarify the underlying mechanisms that enable this broadband responsiveness.",

author = "Ambattu, \{Lizebona August\} and Lorenzo Moroni and Yeo, \{Leslie Y.\}",

year = "2026",

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doi = "10.1038/s44222-026-00420-y",

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AU - Ambattu, Lizebona August

AU - Moroni, Lorenzo

AU - Yeo, Leslie Y.

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N2 - Cells can respond to vibrational frequencies beyond physiological frequency ranges, including those in the ultrasonic domain. Independent, standardized experiments that probe mechanotransduction across frequencies and vibration modalities could clarify the underlying mechanisms that enable this broadband responsiveness.

AB - Cells can respond to vibrational frequencies beyond physiological frequency ranges, including those in the ultrasonic domain. Independent, standardized experiments that probe mechanotransduction across frequencies and vibration modalities could clarify the underlying mechanisms that enable this broadband responsiveness.

U2 - 10.1038/s44222-026-00420-y

DO - 10.1038/s44222-026-00420-y

M3 - Editorial

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VL - 4

SP - 394

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JO - Nature reviews bioengineering

JF - Nature reviews bioengineering

IS - 5

ER -

A universal membrane-centric mechanotransduction mechanism for vibrationally stimulated cells

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