A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis

M. Jaeger; M. Pinelli; M. Borghi; C. Constantini; M. Dindo; L. van Emst; M. Puccetti; M. Pariano; I. Ricano-Ponce; C. Bull; M. S. Gresnigt; X. Wang; J. Gutierrez Achury; C. W. M. Jacobs; N. Xu; M. Oosting; P. Arts; L. A. B. Joosten; F. L. van de Veerdonk; J. A. Veltman; J. ten Oever; B. J. Kullberg; M. Feng; G. J. Adema; C. Wijmenga; V. Kumar; J. Sobel; C. Gilissen; L. Romani; M. G. Netea

doi:10.1126/scitranslmed.aar3558

A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis

M. Jaeger, M. Pinelli, M. Borghi, C. Constantini, M. Dindo, L. van Emst, M. Puccetti, M. Pariano, I. Ricano-Ponce, C. Bull, M. S. Gresnigt, X. Wang, J. Gutierrez Achury, C. W. M. Jacobs, N. Xu, M. Oosting, P. Arts, L. A. B. Joosten, F. L. van de Veerdonk, J. A. VeltmanJ. ten Oever, B. J. Kullberg, M. Feng, G. J. Adema, C. Wijmenga, V. Kumar, J. Sobel, C. Gilissen, L. Romani, M. G. Netea^*

^*Corresponding author for this work

GROW - Reproductive and Perinatal Medicine

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	3558
Number of pages	12
Journal	Science Translational Medicine
Volume	11
Issue number	496
DOIs	https://doi.org/10.1126/scitranslmed.aar3558
Publication status	Published - 12 Jun 2019

Keywords

MANNOSE-BINDING LECTIN
GENE POLYMORPHISM
OSTEOCLAST DIFFERENTIATION
EPIDEMIOLOGY
ASSOCIATION
ALBICANS
CELLS
WOMEN
PATHOGENESIS
PREVALENCE

Access to Document

10.1126/scitranslmed.aar3558

Cite this

Jaeger, M., Pinelli, M., Borghi, M., Constantini, C., Dindo, M., van Emst, L., Puccetti, M., Pariano, M., Ricano-Ponce, I., Bull, C., Gresnigt, M. S., Wang, X., Achury, J. G., Jacobs, C. W. M., Xu, N., Oosting, M., Arts, P., Joosten, L. A. B., van de Veerdonk, F. L., ... Netea, M. G. (2019). A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis. Science Translational Medicine, 11(496), [3558]. https://doi.org/10.1126/scitranslmed.aar3558

Jaeger, M. ; Pinelli, M. ; Borghi, M. ; Constantini, C. ; Dindo, M. ; van Emst, L. ; Puccetti, M. ; Pariano, M. ; Ricano-Ponce, I. ; Bull, C. ; Gresnigt, M. S. ; Wang, X. ; Achury, J. Gutierrez ; Jacobs, C. W. M. ; Xu, N. ; Oosting, M. ; Arts, P. ; Joosten, L. A. B. ; van de Veerdonk, F. L. ; Veltman, J. A. ; ten Oever, J. ; Kullberg, B. J. ; Feng, M. ; Adema, G. J. ; Wijmenga, C. ; Kumar, V. ; Sobel, J. ; Gilissen, C. ; Romani, L. ; Netea, M. G. / A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis. In: Science Translational Medicine. 2019 ; Vol. 11, No. 496.

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title = "A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis",

keywords = "MANNOSE-BINDING LECTIN, GENE POLYMORPHISM, OSTEOCLAST DIFFERENTIATION, EPIDEMIOLOGY, ASSOCIATION, ALBICANS, CELLS, WOMEN, PATHOGENESIS, PREVALENCE",

author = "M. Jaeger and M. Pinelli and M. Borghi and C. Constantini and M. Dindo and {van Emst}, L. and M. Puccetti and M. Pariano and I. Ricano-Ponce and C. Bull and Gresnigt, {M. S.} and X. Wang and Achury, {J. Gutierrez} and Jacobs, {C. W. M.} and N. Xu and M. Oosting and P. Arts and Joosten, {L. A. B.} and {van de Veerdonk}, {F. L.} and Veltman, {J. A.} and {ten Oever}, J. and Kullberg, {B. J.} and M. Feng and Adema, {G. J.} and C. Wijmenga and V. Kumar and J. Sobel and C. Gilissen and L. Romani and Netea, {M. G.}",

year = "2019",

month = jun,

day = "12",

doi = "10.1126/scitranslmed.aar3558",

language = "English",

volume = "11",

journal = "Science Translational Medicine",

issn = "1946-6234",

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Jaeger, M, Pinelli, M, Borghi, M, Constantini, C, Dindo, M, van Emst, L, Puccetti, M, Pariano, M, Ricano-Ponce, I, Bull, C, Gresnigt, MS, Wang, X, Achury, JG, Jacobs, CWM, Xu, N, Oosting, M, Arts, P, Joosten, LAB, van de Veerdonk, FL, Veltman, JA, ten Oever, J, Kullberg, BJ, Feng, M, Adema, GJ, Wijmenga, C, Kumar, V, Sobel, J, Gilissen, C, Romani, L & Netea, MG 2019, 'A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis', Science Translational Medicine, vol. 11, no. 496, 3558. https://doi.org/10.1126/scitranslmed.aar3558

A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis. / Jaeger, M.; Pinelli, M.; Borghi, M.; Constantini, C.; Dindo, M.; van Emst, L.; Puccetti, M.; Pariano, M.; Ricano-Ponce, I.; Bull, C.; Gresnigt, M. S.; Wang, X.; Achury, J. Gutierrez; Jacobs, C. W. M.; Xu, N.; Oosting, M.; Arts, P.; Joosten, L. A. B.; van de Veerdonk, F. L.; Veltman, J. A.; ten Oever, J.; Kullberg, B. J.; Feng, M.; Adema, G. J.; Wijmenga, C.; Kumar, V.; Sobel, J.; Gilissen, C.; Romani, L.; Netea, M. G.

In: Science Translational Medicine, Vol. 11, No. 496, 3558, 12.06.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A systems genomics approach identifies SIGLEC15 as a susceptibility factor in recurrent vulvovaginal candidiasis

AU - Jaeger, M.

AU - Pinelli, M.

AU - Borghi, M.

AU - Constantini, C.

AU - Dindo, M.

AU - van Emst, L.

AU - Puccetti, M.

AU - Pariano, M.

AU - Ricano-Ponce, I.

AU - Bull, C.

AU - Gresnigt, M. S.

AU - Wang, X.

AU - Achury, J. Gutierrez

AU - Jacobs, C. W. M.

AU - Xu, N.

AU - Oosting, M.

AU - Arts, P.

AU - Joosten, L. A. B.

AU - van de Veerdonk, F. L.

AU - Veltman, J. A.

AU - ten Oever, J.

AU - Kullberg, B. J.

AU - Feng, M.

AU - Adema, G. J.

AU - Wijmenga, C.

AU - Kumar, V.

AU - Sobel, J.

AU - Gilissen, C.

AU - Romani, L.

AU - Netea, M. G.

PY - 2019/6/12

Y1 - 2019/6/12

KW - MANNOSE-BINDING LECTIN

KW - GENE POLYMORPHISM

KW - OSTEOCLAST DIFFERENTIATION

KW - EPIDEMIOLOGY

KW - ASSOCIATION

KW - ALBICANS

KW - CELLS

KW - WOMEN

KW - PATHOGENESIS

KW - PREVALENCE

U2 - 10.1126/scitranslmed.aar3558

DO - 10.1126/scitranslmed.aar3558

M3 - Article

VL - 11

JO - Science Translational Medicine

JF - Science Translational Medicine

SN - 1946-6234

IS - 496

M1 - 3558

ER -