A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding

Romy M. W. Kremers, Y.P.J. Bosch, Saartje Bloemen, Bas de Laat, Patrick W. Weerwind, Bas Mochtar, Jos G. Maessen, Rob J. Wagenvoord, Raed Al Dieri, H. Coenraad Hemker

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)442-451
JournalThrombosis and Haemostasis
Issue number3
Publication statusPublished - Sep 2016


  • Cardiopulmonary bypass
  • thrombin generation
  • thrombin inactivation
  • prothrombin conversion
  • transfusion

Cite this