A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding

Romy M. W. Kremers; Y.P.J. Bosch; Saartje Bloemen; Bas de Laat; Patrick W. Weerwind; Bas Mochtar; Jos G. Maessen; Rob J. Wagenvoord; Raed Al Dieri; H. Coenraad Hemker

doi:10.1160/TH16-02-0094

A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding

Romy M. W. Kremers^*, Y.P.J. Bosch, Saartje Bloemen, Bas de Laat, Patrick W. Weerwind, Bas Mochtar, Jos G. Maessen, Rob J. Wagenvoord, Raed Al Dieri, H. Coenraad Hemker

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	442-451
Journal	Thrombosis and Haemostasis
Volume	116
Issue number	3
DOIs	https://doi.org/10.1160/TH16-02-0094
Publication status	Published - Sep 2016

Keywords

Cardiopulmonary bypass
thrombin generation
thrombin inactivation
prothrombin conversion
transfusion

Access to Document

10.1160/TH16-02-0094

Cite this

Kremers, R. M. W., Bosch, Y. P. J., Bloemen, S., de Laat, B., Weerwind, P. W., Mochtar, B., Maessen, J. G., Wagenvoord, R. J., Al Dieri, R., & Hemker, H. C. (2016). A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding. Thrombosis and Haemostasis, 116(3), 442-451. https://doi.org/10.1160/TH16-02-0094

Kremers, Romy M. W. ; Bosch, Y.P.J. ; Bloemen, Saartje ; de Laat, Bas ; Weerwind, Patrick W. ; Mochtar, Bas ; Maessen, Jos G. ; Wagenvoord, Rob J. ; Al Dieri, Raed ; Hemker, H. Coenraad. / A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding. In: Thrombosis and Haemostasis. 2016 ; Vol. 116, No. 3. pp. 442-451.

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title = "A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding",

keywords = "Cardiopulmonary bypass, thrombin generation, thrombin inactivation, prothrombin conversion, transfusion",

author = "Kremers, {Romy M. W.} and Y.P.J. Bosch and Saartje Bloemen and {de Laat}, Bas and Weerwind, {Patrick W.} and Bas Mochtar and Maessen, {Jos G.} and Wagenvoord, {Rob J.} and {Al Dieri}, Raed and Hemker, {H. Coenraad}",

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A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding. / Kremers, Romy M. W.; Bosch, Y.P.J.; Bloemen, Saartje; de Laat, Bas; Weerwind, Patrick W.; Mochtar, Bas; Maessen, Jos G.; Wagenvoord, Rob J.; Al Dieri, Raed; Hemker, H. Coenraad.

In: Thrombosis and Haemostasis, Vol. 116, No. 3, 09.2016, p. 442-451.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A reduction of prothrombin conversion by cardiac surgery with cardiopulmonary bypass shifts the haemostatic balance towards bleeding

AU - Kremers, Romy M. W.

AU - Bosch, Y.P.J.

AU - Bloemen, Saartje

AU - de Laat, Bas

AU - Weerwind, Patrick W.

AU - Mochtar, Bas

AU - Maessen, Jos G.

AU - Wagenvoord, Rob J.

AU - Al Dieri, Raed

AU - Hemker, H. Coenraad

PY - 2016/9

Y1 - 2016/9

KW - Cardiopulmonary bypass

KW - thrombin generation

KW - thrombin inactivation

KW - prothrombin conversion

KW - transfusion

U2 - 10.1160/TH16-02-0094

DO - 10.1160/TH16-02-0094

M3 - Article

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VL - 116

SP - 442

EP - 451

JO - Thrombosis and Haemostasis

JF - Thrombosis and Haemostasis

SN - 0340-6245

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ER -