A randomized controlled TRIal of cognitive BEhavioral therapy for high Catastrophizing in patients undergoing lumbar fusion surgery: the TRIBECA study

P. Scarone*, A. Y. J. M. Smeets, S. M. J. van Kuijk, H. van Santbrink, M. Peters, E. Koetsier

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Web of Science)

Abstract

BackgroundAround 20% of patients undergoing spinal fusion surgery have persistent back or leg pain despite surgery. Pain catastrophizing is the strongest psychological predictor for chronic postsurgical pain. Psychological variables are modifiable and could be target for intervention. However, randomized controlled trials evaluating the effectiveness of psychological interventions to reduce chronic pain and disability after spinal fusion in a population of patients with high preoperative pain catastrophizing scores are missing. The aim of our study is to examine whether an intervention targeting pain catastrophizing mitigates the risk of chronic postsurgical pain and disability. Our primary hypothesis is that targeted perioperative cognitive behavioral therapy decreases the risk of chronic postsurgical pain and disability after spinal fusion surgery in high catastrophizing patients.MethodsWe will perform a two-center prospective, single-blind, randomized, controlled study comparing lumbar spinal fusion surgery outcome between 2 cohorts. Adult patients selected for lumbar spinal fusion with decompression surgery and a minimum score of 24 on the pain catastrophizing scale will be randomized with 1:1 allocation for either perioperative cognitive behavioral therapy (intervention group) or a perioperative education plus progressive exercise program (control group). Patients randomized to the intervention group will receive six individual sessions of cognitive behavioral therapy, two sessions before the operation and four after. Primary outcome is the Core Outcome Measures Index at 12months. Secondary outcomes include pain, disability, depression and quality of life.DiscussionThis is the first trial that evaluates the effectiveness of cognitive behavioral therapy as a perioperative tool to improve pain and disability after spinal fusion surgery in comparison with an educational/exercise control intervention, in patients with high levels of pain catastrophizing. If perioperative cognitive behavioral therapy proves to be effective, this might have important clinical implications, reducing the incidence of chronic postsurgical pain and improving outcome after spinal fusion surgery.Trial registrationClinicaltrials (NCT03969602). Registered 31 May 2019,

Original languageEnglish
Article number810
Number of pages12
JournalBMC Musculoskeletal Disorders
Volume21
Issue number1
DOIs
Publication statusPublished - 4 Dec 2020

Keywords

  • Lumbar spinal fusion surgery
  • Pedicle screws
  • Pain catastrophizing
  • Cognitive behavioral therapy (CBT)
  • Education
  • Chronic postsurgical pain (CPSP)
  • CHRONIC POSTSURGICAL PAIN
  • LOW-BACK-PAIN
  • OUTCOME MEASURES
  • SPONDYLOLISTHESIS
  • REHABILITATION
  • COMPLICATIONS
  • INDIVIDUALS
  • PREDICTORS
  • DEPRESSION
  • MANAGEMENT

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