A painful neuropathy-associated Nav1.7 mutant leads to time-dependent degeneration of small-diameter axons associated with intracellular Ca2+ dysregulation and decrease in ATP levels

Harshvardhan Rolyan, Shujun Liu, Janneke G. J. Hoeijmakers, Karin Faber, Ingemar S. J. Merkies, Giuseppe Lauria, Joel A. Black, Stephen G. Waxman*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1-13
JournalMolecular Pain
Publication statusPublished - 7 Nov 2016


  • ATP
  • axon degeneration
  • mitochondria
  • peripheral neuropathy
  • reactive oxygen species
  • sodium-calcium exchanger
  • voltage-gated sodium channel

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