A Numerical Method of Reduced Complexity for Simulating Vascular Hemodynamics Using Coupled 0D Lumped and 1D Wave Propagation Models

Wilco Kroon*, Wouter Huberts, Marielle Bosboom, Frans van de Vosse

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


A computational method of reduced complexity is developed for simulating vascular hemodynamics by combination of one-dimensional (1D) wave propagation models for the blood vessels with zero-dimensional (0D) lumped models for the microcirculation. Despite the reduced dimension, current algorithms used to solve the model equations and simulate pressure and flow are rather complex, thereby limiting acceptance in the medical field. This complexity mainly arises from the methods used to combine the 1D and the 0D model equations. In this paper a numerical method is presented that no longer requires additional coupling methods and enables random combinations of 1D and 0D models using pressure as only state variable. The method is applied to a vascular tree consisting of 60 major arteries in the body and the head. Simulated results are realistic. The numerical method is stable and shows good convergence.
Original languageEnglish
Article number156094
JournalComputational and Mathematical Methods in Medicine
Publication statusPublished - 2012

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