TY - JOUR
T1 - A New 35-mm Short Intra-aortic Balloon Catheter A Suitable Option Also for Non-Small-Sized Patients?
AU - Gelsomino, Sandro
AU - Lozekoot, Pieter Willem
AU - Lorusso, Roberto
AU - de Jong, Monique Maria
AU - Parise, Orlando
AU - Matteucci, Francesco
AU - Luca, Fabiana
AU - Kumar, Narendra
AU - Dehkord, Eshan Sadeghian
AU - Romano, Salvatore Mario
AU - Gensini, Gian Franco
AU - La Meir, Mark
AU - Maessen, Josephus Gregorius
PY - 2016
Y1 - 2016
N2 - Objective: Visceral ischemia can be a potentially life-threatening complication of intra-aortic balloon pump (IABP) support. A shorter IABP catheter might lead to a reduction of visceral complications. In this animal study, we evaluate the effects of a 35-mL short catheter in comparison with a 40-mL standard-sized catheter. Methods: Eighteen healthy swine underwent 120-minute ligation of the left anterior descending coronary artery followed by 6 hours of reperfusion being supported by either a short IABP catheter (short group) (n = 6) or a long IABP catheter (long group) (n = 6) or with no assistance (controls) (n = 6). Hemodynamics, visceral and coronary flows, as well as biochemical markers were evaluated throughout the different phases of the protocol. Results: Mesenteric flows increased significantly at reperfusion (P <0.001 both) remaining constant afterward (all, P > 0.05) in the short group, while remaining significantly lower in the long group at the start of reperfusion, remaining constantly lower than the short group and controls (P <0.001 vs short, P <0.003 vs controls). In both long and short groups, catheters improved renal flows at reperfusion (P <0.001 both) without any further variation (P > 0.05). In the short group, the flows were higher during the whole of reperfusion (all, P <0.05). Intraaortic balloon pump support improved hemodynamic indices and coronary blood flows during reperfusion to a similar extent in both the small and the long group (P > 0.05). Conclusions: The short IABP catheter proved to be as effective as the standard-sized catheter in supporting hemodynamics and coronary circulation. Furthermore, it even improves visceral flows in comparison with conventional IABP catheters.
AB - Objective: Visceral ischemia can be a potentially life-threatening complication of intra-aortic balloon pump (IABP) support. A shorter IABP catheter might lead to a reduction of visceral complications. In this animal study, we evaluate the effects of a 35-mL short catheter in comparison with a 40-mL standard-sized catheter. Methods: Eighteen healthy swine underwent 120-minute ligation of the left anterior descending coronary artery followed by 6 hours of reperfusion being supported by either a short IABP catheter (short group) (n = 6) or a long IABP catheter (long group) (n = 6) or with no assistance (controls) (n = 6). Hemodynamics, visceral and coronary flows, as well as biochemical markers were evaluated throughout the different phases of the protocol. Results: Mesenteric flows increased significantly at reperfusion (P <0.001 both) remaining constant afterward (all, P > 0.05) in the short group, while remaining significantly lower in the long group at the start of reperfusion, remaining constantly lower than the short group and controls (P <0.001 vs short, P <0.003 vs controls). In both long and short groups, catheters improved renal flows at reperfusion (P <0.001 both) without any further variation (P > 0.05). In the short group, the flows were higher during the whole of reperfusion (all, P <0.05). Intraaortic balloon pump support improved hemodynamic indices and coronary blood flows during reperfusion to a similar extent in both the small and the long group (P > 0.05). Conclusions: The short IABP catheter proved to be as effective as the standard-sized catheter in supporting hemodynamics and coronary circulation. Furthermore, it even improves visceral flows in comparison with conventional IABP catheters.
KW - Myocardial infarction
KW - Intra-aortic balloon pump
KW - Circulatory support
KW - Visceral ischemia
U2 - 10.1097/IMI.0000000000000233
DO - 10.1097/IMI.0000000000000233
M3 - Article
C2 - 26901748
SN - 1556-9845
VL - 11
SP - 46
EP - 53
JO - Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
JF - Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
IS - 1
ER -