A Multifactorial Approach to Sleep and Its Association with Health-Related Quality of Life in a Multiethnic Asian Working Population: A Cross-Sectional Analysis

Gerard Dunleavy*, Andre Comiran Tonon, Ai Ping Chua, Yichi Zhang, Kei Long Cheung, Thuan-Quoc Thach, Yuri Rykov, Chee-Kiong Soh, Georgios Christopoulos, Hein de Vries, Josip Car

*Corresponding author for this work

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This study aims to explore if objectively and subjectively measured sleep parameters are associated with physical and mental health-related quality of life in a multiethnic working population in Singapore. We performed a cross-sectional analysis with data from 329 full-time employees enrolled in a workplace cohort study in Singapore. The Short-Form 36v2 (SF-36v2) survey was used to assess health-related quality of life, in terms of physical and mental health. Subjective and objective sleep parameters were measured using the Pittsburgh Sleep Quality Index and wrist actigraphy, respectively. Generalized linear modeling was performed to examine the association between sleep parameters and health-related quality of life. After adjusting for confounders, subjectively measured sleep disturbances were associated with a lower physical health-related quality of life, whereas higher, objectively measured sleep efficiency was associated with greater physical health-related quality of life. Subjectively measured daytime dysfunction was associated with impaired mental health-related quality of life. Using both objective and subjective measurements of sleep, the current study suggests that there is an association between sleep and health-related quality of life. Workplace health-promotion planners in Singapore should consider programmes that educate workers on better sleep hygiene practices in an effort to improve sleep and health-related quality of life.

Original languageEnglish
Article number4147
Number of pages14
JournalInternational Journal of Environmental Research and Public Health
Issue number21
Publication statusPublished - 1 Nov 2019


  • sleep quality
  • quality of life
  • workplace health

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