A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet

Gulce Sari, Eric J. Meester, Leonie C. van der Zee, Kristiaan Wouters, Jeanine R. van Lennep, Maikel Peppelenbosch, Andre Boonstra, Kim Van der Heiden, Monique M. T. Mulder, Thomas Vanwolleghem

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)510-515
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume524
Issue number2
DOIs
Publication statusPublished - 2 Apr 2020

Keywords

  • Human liver chimeric mouse model
  • Atherosclerosis
  • High fat diet
  • Lipoprotein
  • Cardiovascular disease
  • HUMAN HEPATOCYTES
  • VIRUS-INFECTION
  • CHIMERIC MICE
  • C VIRUS
  • THERAPY

Cite this

Sari, G., Meester, E. J., van der Zee, L. C., Wouters, K., van Lennep, J. R., Peppelenbosch, M., Boonstra, A., Van der Heiden, K., Mulder, M. M. T., & Vanwolleghem, T. (2020). A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet. Biochemical and Biophysical Research Communications, 524(2), 510-515. https://doi.org/10.1016/j.bbrc.2020.01.067