A mouse model of humanized liver shows a human-like lipid profile, but does not form atherosclerotic plaque after western type diet

Gulce Sari*, Eric J. Meester, Leonie C. van der Zee, Kristiaan Wouters, Jeanine R. van Lennep, Maikel Peppelenbosch, Andre Boonstra, Kim Van der Heiden, Monique M. T. Mulder, Thomas Vanwolleghem*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)510-515
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume524
Issue number2
DOIs
Publication statusPublished - 2 Apr 2020

Keywords

  • Human liver chimeric mouse model
  • Atherosclerosis
  • High fat diet
  • Lipoprotein
  • Cardiovascular disease
  • HUMAN HEPATOCYTES
  • VIRUS-INFECTION
  • CHIMERIC MICE
  • C VIRUS
  • THERAPY

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