A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex

Sarah J. Marzi, Szi Kay Leung, Teodora Ribarska, Eilis Hannon, Adam R. Smith, Ehsan Pishva, Jeremie Poschmann, Karen Moore, Claire Troakes, Safa Al-Sarraj, Stephan Beck, Stuart Newman, Katie Lunnon, Leonard C. Schalkwyk, Jonathan Mill

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1618-1627
Number of pages17
JournalNature Neuroscience
Volume21
Issue number11
DOIs
Publication statusPublished - 1 Nov 2018

Keywords

  • AMYLOID PRECURSOR PROTEIN
  • DNA METHYLATION
  • GENE-EXPRESSION
  • BRAIN
  • NEURODEGENERATION
  • QUANTIFICATION
  • PRESENILIN-1
  • ACETYLATION
  • PROGRESSION
  • HYPOTHESIS

Cite this

Marzi, S. J., Leung, S. K., Ribarska, T., Hannon, E., Smith, A. R., Pishva, E., Poschmann, J., Moore, K., Troakes, C., Al-Sarraj, S., Beck, S., Newman, S., Lunnon, K., Schalkwyk, L. C., & Mill, J. (2018). A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience, 21(11), 1618-1627. https://doi.org/10.1038/s41593-018-0253-7