A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy

Matthew Alsaloum; Mark Estacion; Rowida Almomani; Monique M. Gerrits; Gidon J. Boenhof; Dan Ziegler; Rayaz Malik; Maryam Ferdousi; Giuseppe Lauria; Ingemar S. J. Merkies; Catharina G. Faber; Sulayman Dib-Hajj; Stephen G. Waxman; B. de Greef; J. G. J. Hoeijmakers; M. Sopacua; H. J. M. Smeets; J. M. Vanoevelen; null Eijkenboom; P. Lindsey; R. Almomani; M. Taiana; M. Marchi; R. Lombardi; D. Cazzato; F. M. Boneschi; A. Zauli; F. Clarelli; S. Santoro; A.B. Lopez; A. Quattrini; S. Cestele; O. Chever; M. Tavakoli; R. Malik; D. Kapetis; M. N. Xenakis; M. Mantegazza; F. Battiato; A. Strom; PROPANE Study Grp

doi:10.1177/1744806919849802

A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy

Matthew Alsaloum, Mark Estacion, Rowida Almomani, Monique M. Gerrits, Gidon J. Boenhof, Dan Ziegler, Rayaz Malik, Maryam Ferdousi, Giuseppe Lauria, Ingemar S. J. Merkies, Catharina G. Faber, Sulayman Dib-Hajj, Stephen G. Waxman^*, B. de Greef, J. G. J. Hoeijmakers, M. Sopacua, H. J. M. Smeets, J. M. Vanoevelen, Eijkenboom, P. LindseyR. Almomani, M. Taiana, M. Marchi, R. Lombardi, D. Cazzato, F. M. Boneschi, A. Zauli, F. Clarelli, S. Santoro, A.B. Lopez, A. Quattrini, S. Cestele, O. Chever, M. Tavakoli, R. Malik, D. Kapetis, M. N. Xenakis, M. Mantegazza, F. Battiato, A. Strom, PROPANE Study Grp

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	1744806919849802
Pages (from-to)	1-14
Number of pages	14
Journal	Molecular Pain
Volume	15
DOIs	https://doi.org/10.1177/1744806919849802
Publication status	Published - May 2019

Keywords

Diabetic neuropathy
voltage-gated sodium channels
sodium channel beta-subunits
neuropathic pain
FAST INACTIVATION
NA(V)1.8 MUTATION
ALPHA-SUBUNIT
SEGMENT IVS6
DOMAIN IV
EXCITABILITY
ACTIVATION
NEURONS
PREVALENCE
POTENTIALS

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10.1177/1744806919849802

Cite this

Alsaloum, M., Estacion, M., Almomani, R., Gerrits, M. M., Boenhof, G. J., Ziegler, D., Malik, R., Ferdousi, M., Lauria, G., Merkies, I. S. J., Faber, C. G., Dib-Hajj, S., Waxman, S. G., de Greef, B., Hoeijmakers, J. G. J., Sopacua, M., Smeets, H. J. M., Vanoevelen, J. M., Eijkenboom, ... PROPANE Study Grp (2019). A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy. Molecular Pain, 15, 1-14. [1744806919849802]. https://doi.org/10.1177/1744806919849802

Alsaloum, Matthew ; Estacion, Mark ; Almomani, Rowida ; Gerrits, Monique M. ; Boenhof, Gidon J. ; Ziegler, Dan ; Malik, Rayaz ; Ferdousi, Maryam ; Lauria, Giuseppe ; Merkies, Ingemar S. J. ; Faber, Catharina G. ; Dib-Hajj, Sulayman ; Waxman, Stephen G. ; de Greef, B. ; Hoeijmakers, J. G. J. ; Sopacua, M. ; Smeets, H. J. M. ; Vanoevelen, J. M. ; Eijkenboom ; Lindsey, P. ; Almomani, R. ; Taiana, M. ; Marchi, M. ; Lombardi, R. ; Cazzato, D. ; Boneschi, F. M. ; Zauli, A. ; Clarelli, F. ; Santoro, S. ; Lopez, A.B. ; Quattrini, A. ; Cestele, S. ; Chever, O. ; Tavakoli, M. ; Malik, R. ; Kapetis, D. ; Xenakis, M. N. ; Mantegazza, M. ; Battiato, F. ; Strom, A. ; PROPANE Study Grp. / A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy. In: Molecular Pain. 2019 ; Vol. 15. pp. 1-14.

@article{c60750feeb504075938d3de9a62d4b0d,

title = "A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy",

keywords = "Diabetic neuropathy, voltage-gated sodium channels, sodium channel beta-subunits, neuropathic pain, FAST INACTIVATION, NA(V)1.8 MUTATION, ALPHA-SUBUNIT, SEGMENT IVS6, DOMAIN IV, EXCITABILITY, ACTIVATION, NEURONS, PREVALENCE, POTENTIALS",

author = "Matthew Alsaloum and Mark Estacion and Rowida Almomani and Gerrits, {Monique M.} and Boenhof, {Gidon J.} and Dan Ziegler and Rayaz Malik and Maryam Ferdousi and Giuseppe Lauria and Merkies, {Ingemar S. J.} and Faber, {Catharina G.} and Sulayman Dib-Hajj and Waxman, {Stephen G.} and {de Greef}, B. and Hoeijmakers, {J. G. J.} and M. Sopacua and Smeets, {H. J. M.} and Vanoevelen, {J. M.} and Eijkenboom and P. Lindsey and R. Almomani and M. Taiana and M. Marchi and R. Lombardi and D. Cazzato and Boneschi, {F. M.} and A. Zauli and F. Clarelli and S. Santoro and A.B. Lopez and A. Quattrini and S. Cestele and O. Chever and M. Tavakoli and R. Malik and D. Kapetis and Xenakis, {M. N.} and M. Mantegazza and F. Battiato and A. Strom and {PROPANE Study Grp}",

year = "2019",

month = may,

doi = "10.1177/1744806919849802",

language = "English",

volume = "15",

pages = "1--14",

journal = "Molecular Pain",

issn = "1744-8069",

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Alsaloum, M, Estacion, M, Almomani, R, Gerrits, MM, Boenhof, GJ, Ziegler, D, Malik, R, Ferdousi, M, Lauria, G, Merkies, ISJ , Faber, CG, Dib-Hajj, S, Waxman, SG, de Greef, B , Hoeijmakers, JGJ , Sopacua, M , Smeets, HJM , Vanoevelen, JM, Eijkenboom, Lindsey, P, Almomani, R, Taiana, M, Marchi, M, Lombardi, R, Cazzato, D, Boneschi, FM, Zauli, A, Clarelli, F, Santoro, S, Lopez, AB, Quattrini, A, Cestele, S, Chever, O, Tavakoli, M, Malik, R, Kapetis, D, Xenakis, MN, Mantegazza, M, Battiato, F, Strom, A & PROPANE Study Grp 2019, 'A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy', Molecular Pain, vol. 15, 1744806919849802, pp. 1-14. https://doi.org/10.1177/1744806919849802

A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy. / Alsaloum, Matthew; Estacion, Mark; Almomani, Rowida; Gerrits, Monique M.; Boenhof, Gidon J.; Ziegler, Dan; Malik, Rayaz; Ferdousi, Maryam; Lauria, Giuseppe; Merkies, Ingemar S. J.; Faber, Catharina G.; Dib-Hajj, Sulayman; Waxman, Stephen G.; de Greef, B.; Hoeijmakers, J. G. J.; Sopacua, M.; Smeets, H. J. M.; Vanoevelen, J. M.; Eijkenboom; Lindsey, P.; Almomani, R.; Taiana, M.; Marchi, M.; Lombardi, R.; Cazzato, D.; Boneschi, F. M.; Zauli, A.; Clarelli, F.; Santoro, S.; Lopez, A.B.; Quattrini, A.; Cestele, S.; Chever, O.; Tavakoli, M.; Malik, R.; Kapetis, D.; Xenakis, M. N.; Mantegazza, M.; Battiato, F.; Strom, A.; PROPANE Study Grp.

In: Molecular Pain, Vol. 15, 1744806919849802, 05.2019, p. 1-14.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A gain-of-function sodium channel beta 2-subunit mutation in painful diabetic neuropathy

AU - Alsaloum, Matthew

AU - Estacion, Mark

AU - Almomani, Rowida

AU - Gerrits, Monique M.

AU - Boenhof, Gidon J.

AU - Ziegler, Dan

AU - Malik, Rayaz

AU - Ferdousi, Maryam

AU - Lauria, Giuseppe

AU - Merkies, Ingemar S. J.

AU - Faber, Catharina G.

AU - Dib-Hajj, Sulayman

AU - Waxman, Stephen G.

AU - de Greef, B.

AU - Hoeijmakers, J. G. J.

AU - Sopacua, M.

AU - Smeets, H. J. M.

AU - Vanoevelen, J. M.

AU - Eijkenboom, null

AU - Lindsey, P.

AU - Almomani, R.

AU - Taiana, M.

AU - Marchi, M.

AU - Lombardi, R.

AU - Cazzato, D.

AU - Boneschi, F. M.

AU - Zauli, A.

AU - Clarelli, F.

AU - Santoro, S.

AU - Lopez, A.B.

AU - Quattrini, A.

AU - Cestele, S.

AU - Chever, O.

AU - Tavakoli, M.

AU - Malik, R.

AU - Kapetis, D.

AU - Xenakis, M. N.

AU - Mantegazza, M.

AU - Battiato, F.

AU - Strom, A.

AU - PROPANE Study Grp

PY - 2019/5

Y1 - 2019/5

KW - Diabetic neuropathy

KW - voltage-gated sodium channels

KW - sodium channel beta-subunits

KW - neuropathic pain

KW - FAST INACTIVATION

KW - NA(V)1.8 MUTATION

KW - ALPHA-SUBUNIT

KW - SEGMENT IVS6

KW - DOMAIN IV

KW - EXCITABILITY

KW - ACTIVATION

KW - NEURONS

KW - PREVALENCE

KW - POTENTIALS

U2 - 10.1177/1744806919849802

DO - 10.1177/1744806919849802

M3 - Article

VL - 15

SP - 1

EP - 14

JO - Molecular Pain

JF - Molecular Pain

SN - 1744-8069

M1 - 1744806919849802

ER -