A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF

Georg Summer; Annika R. Kuhn; Chantal Munts; Daniela Miranda-Silva; Adelino F. Leite-Moreira; Andre P. Lourenco; Stephane Heymans; Ines Falcao-Pires; Marc van Bilsen

doi:10.1016/j.yjmcc.2020.05.008

A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF

Georg Summer, Annika R. Kuhn, Chantal Munts, Daniela Miranda-Silva, Adelino F. Leite-Moreira, Andre P. Lourenco, Stephane Heymans, Ines Falcao-Pires, Marc van Bilsen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	66-75
Number of pages	10
Journal	Journal of Molecular and Cellular Cardiology
Volume	144
DOIs	https://doi.org/10.1016/j.yjmcc.2020.05.008
Publication status	Published - Jul 2020

Keywords

Heart failure
Metabolic syndrome
Transcriptomics
Systems biology
Mitochondrial metabolism
PRESERVED EJECTION FRACTION
HEART-FAILURE
PPAR-ALPHA
METABOLIC SYNDROME
EXPRESSION
HYPERTROPHY
DYSFUNCTION
ACTIVATION
MYC

Access to Document

10.1016/j.yjmcc.2020.05.008

Cite this

Summer, Georg ; Kuhn, Annika R. ; Munts, Chantal ; Miranda-Silva, Daniela ; Leite-Moreira, Adelino F. ; Lourenco, Andre P. ; Heymans, Stephane ; Falcao-Pires, Ines ; van Bilsen, Marc. / A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF. In: Journal of Molecular and Cellular Cardiology. 2020 ; Vol. 144. pp. 66-75.

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title = "A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF",

keywords = "Heart failure, Metabolic syndrome, Transcriptomics, Systems biology, Mitochondrial metabolism, PRESERVED EJECTION FRACTION, HEART-FAILURE, PPAR-ALPHA, METABOLIC SYNDROME, EXPRESSION, HYPERTROPHY, DYSFUNCTION, ACTIVATION, MYC",

author = "Georg Summer and Kuhn, {Annika R.} and Chantal Munts and Daniela Miranda-Silva and Leite-Moreira, {Adelino F.} and Lourenco, {Andre P.} and Stephane Heymans and Ines Falcao-Pires and {van Bilsen}, Marc",

year = "2020",

month = jul,

doi = "10.1016/j.yjmcc.2020.05.008",

language = "English",

volume = "144",

pages = "66--75",

journal = "Journal of Molecular and Cellular Cardiology",

issn = "0022-2828",

publisher = "ELSEVIER SCI LTD",

}

A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF. / Summer, Georg ; Kuhn, Annika R.; Munts, Chantal; Miranda-Silva, Daniela; Leite-Moreira, Adelino F.; Lourenco, Andre P.; Heymans, Stephane; Falcao-Pires, Ines; van Bilsen, Marc.

In: Journal of Molecular and Cellular Cardiology, Vol. 144, 07.2020, p. 66-75.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF

AU - Summer, Georg

AU - Kuhn, Annika R.

AU - Munts, Chantal

AU - Miranda-Silva, Daniela

AU - Leite-Moreira, Adelino F.

AU - Lourenco, Andre P.

AU - Heymans, Stephane

AU - Falcao-Pires, Ines

AU - van Bilsen, Marc

PY - 2020/7

Y1 - 2020/7

KW - Heart failure

KW - Metabolic syndrome

KW - Transcriptomics

KW - Systems biology

KW - Mitochondrial metabolism

KW - PRESERVED EJECTION FRACTION

KW - HEART-FAILURE

KW - PPAR-ALPHA

KW - METABOLIC SYNDROME

KW - EXPRESSION

KW - HYPERTROPHY

KW - DYSFUNCTION

KW - ACTIVATION

KW - MYC

U2 - 10.1016/j.yjmcc.2020.05.008

DO - 10.1016/j.yjmcc.2020.05.008

M3 - Article

C2 - 32422321

VL - 144

SP - 66

EP - 75

JO - Journal of Molecular and Cellular Cardiology

JF - Journal of Molecular and Cellular Cardiology

SN - 0022-2828

ER -