A Delphi study and International Consensus Recommendations: The use of bolus in the setting of postmastectomy radiation therapy for early breast cancer

O. Kaidar-Person*, H.M. Dahn, A.M. Nichol, L.J. Boersma, D. de Ruysscher, I. Meattini, J.P. Pignol, C. Aristei, Y. Belkacemi, D. Benjamin, N. Bese, C.E. Coles, P. Franco, A.Y. Ho, S. Hol, R. Jagsi, A.M. Kirby, L. Marrazzo, G.N. Marta, M.S. MoranH.D. Nissen, V. Strnad, Y. Zissiadis, P.M. Poortmans, B.V. Offersen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Bolus serves as a tissue equivalent material that shifts the 95-100% isodose line towards the skin and subcutaneous tissue. The need for bolus for all breast cancer patients planned for postmastectomy radiation therapy (PMRT) has been questioned. The work was initiated by the faculty of the European SocieTy for Radiotherapy & Oncology (ESTRO) breast cancer courses and represents a multidisciplinary international breast cancer expert collaboration to optimize PMRT. Due to the lack of randomised trials evaluating the benefits of bolus, we designed a stepwise project to evaluate the existing evidence about the use of bolus in the setting of PMRT to achieve an international consensus for the indications of bolus in PMRT, based on the Delphi method. (c) 2021 Elsevier B.V. All rights reserved. Radiotherapy and Oncology 164 (2021) 115-121
Original languageEnglish
Pages (from-to)115-121
Number of pages7
JournalRadiotherapy and Oncology
Volume164
DOIs
Publication statusPublished - 1 Nov 2021

Keywords

  • Breast cancer
  • Mastectomy
  • Radiation therapy
  • PMRT
  • Bolus
  • Tissue compensator
  • SKIN-SPARING MASTECTOMY
  • CLINICAL-PRACTICE GUIDELINES
  • TARGET VOLUME DELINEATION
  • CARCINOMA-IN-SITU
  • LOCAL RECURRENCE
  • CHEST-WALL
  • REGIONAL RECURRENCE
  • PREDICTIVE FACTORS
  • AMERICAN-SOCIETY
  • RESIDUAL DISEASE

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