Abstract
Objective: Many EEG studies have reported that ADHD is characterized by elevated Theta/Beta ratio (TBR). In this study we conducted a meta-analysis on the TBR in ADHD. Method: TBR data during Eyes Open from location Cz were analyzed from children/adolescents 6-18 years of age with and without ADHD. Results: Nine studies were identified with a total of 1253 children/adolescents with and 517 without ADHD. The grand-mean effect size (ES) for the 6-13 year-olds was 0.75 and for the 6-18 year-olds was 0.62. However the test for heterogeneity remained significant; therefore these ESs are misleading and considered an overestimation. Post-hoc analysis found a decreasing difference in TBR across years, explained by an increasing TBR for the non-ADHD groups. Conclusion: Excessive TBR cannot be considered a reliable diagnostic measure of ADHD, however a substantial sub-group of ADHD patients do deviate on this measure and TBR has prognostic value in this sub-group, warranting its use as a prognostic measure rather than a diagnostic measure.
| Original language | English |
|---|---|
| Pages (from-to) | 374-383 |
| Number of pages | 10 |
| Journal | Journal of Attention Disorders |
| Volume | 17 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Jul 2013 |
| Externally published | Yes |
Keywords
- ADHD
- EEG
- QEEG
- theta
- beta
- Theta/Beta ratio
- neurofeedback
- DEFICIT-HYPERACTIVITY DISORDER
- ATTENTION-DEFICIT/HYPERACTIVITY DISORDER
- QUANTITATIVE EEG
- BEHAVIORAL-PROBLEMS
- CHILDREN
- SLEEP
- BOYS
- AGE
- ASSOCIATION
- VALIDATION