Since the translational research findings of Benabid and colleagues which partly led to their seminal paper regarding the treatment of mainly tremor dominant Parkinson patients through thalamic high-frequency-stimulation (HFS) in 1987, we still struggle with identifying a satisfactory mechanistic explanation of the underlying principles of deep brain stimulation (DBS). Furthermore, the technological advance of DBS devices (electrodes and implantable pulse generators, IPG's) has shown a distinct lack of dynamic progression. In light of this we argue that it is time to leave the paleolithic age and enter hellenistic times: the device-manufacturing industry and the medical community together should put more emphasis on advancing the technology rather than resting on their laurels.
|Journal||Frontiers in Human Neuroscience|
|Publication status||Published - 17 Sept 2014|
- deep brain stimulation
- functional neurosurgery
- stereotactic operation