A comparison of the corneal biomechanics in pseudoexfoliation glaucoma, primary open-angle glaucoma and healthy controls using Corvis ST

Zia Sultan Pradhan*, Sujit Deshmukh, Shivani Dixit, Shruthi Sreenivasaiah, Sujani Shroff, Sathi Devi, Carroll A. B. Webers, Harsha Laxmana Rao

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Web of Science)

Abstract

Purpose

To compare the corneal biomechanical parameters between pseudoexfoliation glaucoma (PXG), primary open-angle glaucoma (POAG) and healthy controls using Corvis ST.

Methods

A prospective, cross-sectional study was conducted which included 132 treatment-naive eyes which underwent Corvis ST. The study cohort comprised of 44 eyes with PXG, 42 eyes with POAG and 46 healthy controls. Corneal biomechanical parameters, which included corneal velocities, length of corneal applanated surface, deformation amplitude (DA), peak distance and radius of curvature, were compared between the groups using analysis of variance models.

Results

The 3 groups were demographically similar. The mean IOP was 15.7 +/- 3 mmHg in the control group, 21.3 +/- 5 mmHg in the POAG group and 25.8 +/- 7 mmHg in the PXG group (p

Conclusion

Corneal biomechanical parameters measured on Corvis ST are not different between eyes with PXG, POAG and healthy controls after adjusting for IOP.

Original languageEnglish
Article number0241296
Number of pages10
JournalPLOS ONE
Volume15
Issue number10
DOIs
Publication statusPublished - 26 Oct 2020

Keywords

  • EXFOLIATION SYNDROME
  • INTRAOCULAR-PRESSURE
  • DEFORMATION RESPONSE
  • HYSTERESIS
  • PARAMETERS
  • NUMBER
  • IMPACT
  • EYES

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