A Combination of Transcriptomics and Metabolomics Uncovers Enhanced Bile Acid Biosynthesis in HepG2 Cells Expressing CCAAT/Enhancer-Binding Protein beta (C/EBP beta), Hepatocyte Nuclear Factor 4 alpha (HNF4 alpha), and Constitutive Androstane Receptor (CAR)

Marina Blazquez, Aitor Carretero, James K. Ellis, Toby J. Athersuch, Rachel Cavill, Timothy M. D. Ebbels, Hector C. Keun, Jose V. Castell, Agustin Lahoz, Roque Bort*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Web of Science)
11 Downloads (Pure)
Original languageEnglish
Pages (from-to)2732-2741
JournalJournal of Proteome Research
Issue number6
Publication statusPublished - Jun 2013


  • HepG2
  • bile acids
  • hepatic model
  • chenodeoxycholic acid
  • CDCA
  • C/EBP
  • HNF4
  • CAR
  • NMR spectroscopy
  • metabolomics
  • metabonomics

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