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1960

Inhibition of enzymes by Atebrin

Hemker, H. C. & Hülsmann, W. C., 1960, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 44, p. 175-177 3 p.

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1961

Dinitrophenol-induced ATPase of rat-liver mitochondria

Hemker, H. C. & Hülsmann, W. C., 18 Mar 1961, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 48, 1, p. 221-223 3 p.

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1962

A new application of the Clark oxygen electrode

Hemker, H. C., 16 Jul 1962, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 60, 3, p. 646-647 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademic

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Lipid solubility as a factor influencing the activity of uncoupling phenols

Hemker, H. C., 1962, In : Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides. 63, 1, p. 46-54 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

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1963

Nature of prothrombin biosynthesis: Preprothrombininæmia in vitamin K-deficiency

Hemker, H. C., Veltkamp, J. J., Hensen, A. & Loeliger, E. A., 9 Nov 1963, In : Nature. 200, 4906, p. 589-590 2 p.

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

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1964

Behaviour of factors II, VII, IX and X in bleeding complications during long-term treatment with Coumarin

Loeliger, E. A., Hensen, A., Mattern, M. J. & Hemker, H. C., 1 Jan 1964, In : Thrombosis et diathesis haemorrhagica. 10, 3/4, p. 278-281 4 p.

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Kwantitering in de bloedstolling

Hemker, H. C., 1 Jan 1964, In : Maandschrift voor kindergeneeskunde. 22, p. 503-511 9 p.

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The biological disappearance rate of prothrombin, Factors VII, IX and X from plasma in hypothyroidism, hyperthyroidism, and during fever

Loeliger, E. A., van der Esch, B., Mattern, M. J. & Hemker, H. C., 1 Jan 1964, In : Thrombosis et diathesis haemorrhagica. 10, 3-4, p. 267-277 11 p.

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The mode of action of dinitrophenols on the different phosphorylating steps

Hemker, H. C., 1964, In : Biochimica et Biophysica Acta (BBA) - Specialized Section on Enzymological Subjects. 81, 1, p. 9-20 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

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1965

Differentiële leverfunctiebepaling met behulp van de trombotest van Owren

Hemker, H. C., van der Meer, J. & Loeliger, E. A., 3 Apr 1965, In : Nederlands Tijdschrift voor Geneeskunde. 109, 14, p. 646-652 7 p.

Research output: Contribution to journalArticleAcademic

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Kinetic aspects of the interaction of blood clotting enzymes: I. Derivation of basic formulas

Hemker, H. C., Hemker, P. W. & Loeliger, E. A., 1 Jan 1965, In : Thrombosis et diathesis haemorrhagica. 13, 1-2, p. 155-175 21 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic basis of prothrombin estimation particularly with reference to the rectilinearity of the log-log reference curve

Hemker, H. C., van der Meer, J. & Loeliger, E. A., 1965, Genetics and the Interaction of Blood Clotting Factors: Transactions of the Conference Held under the Auspices of the International Committee on Blood Clotting Factors, Amsterdam, The Netherlands, August 1964. Koller, F. & Streuli, F. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 247-252 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Rate of synthesis of coagulation factors II, VII, IX, and X during substitution therapy with P.P.S.B.

Loeliger, E. A., Hensen, A., Mattern, M. J. & Hemker, H. C., 1965, Proceedings of the Tenth Congress of the International Society of Blood Transfusion, Stockholm, September 1964: Part 5: Therapy of Acute Blood Loss and of Coagulation Disorders. Holländer, L. P. (ed.). 1 ed. S. Karger AG, Vol. 5. p. 1346-1347 2 p. (International Society of Blood Transfusion, Vol. 23).

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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The biological half-time of hageman factor

Veltkamp, J. J., Loeliger, E. A. & Hemker, H. C., 26 Mar 1965, In : Thrombosis et diathesis haemorrhagica. 13, 1/2, p. 1-7 7 p.

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1966

A double blind study of phenprocoumon prophylaxis after myocardial infarction

Hensen, A., Kroes, F., van Dyck, L. M., Fekkes, N., Hemker, H. C. & Loeliger, E. A., 1966, Pathogenesis and Treatment of Thromboembolic Diseases, including Coronary, Cerebral and Peripheral Thrombosis: International Symposium, Basle, Switzerland, August 29th-September 1st 1965. Duckert, F. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 333-336 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Quantitation of circulating fibrinogen breakdown products in intravascular clotting

Hemker, H. C., Fekkes, N., Hensen, A., Schrijver, H. & Loeliger, E. A., 1966, Diffuse Intravascular Clotting: Transactions of the Conference Held under the Auspices of the International Committee on Haemostasis and Thrombosis, St. Moritz, Switzerland, September 1965. Brinkhous, K. M., Koller, F., Streuli, F. & Duckert, F. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 227-234 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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1967

A double-blind trial of long-term anticoagulant treatment after myocardial infarction

Loeliger, E. A., Hensen, A., Kroes, F., van Dijk, L. M., Fekkes, N., de Jonge, H. & Hemker, H. C., 1967, In : Journal of Internal Medicine. 182, 5, p. 549-566 18 p.

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Contact activation in the extrinsic blood clotting system

Altman, R. & Hemker, H. C., 1 Jan 1967, In : Thrombosis et diathesis haemorrhagica. 18, 3-4, p. 525-531 7 p.

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Formation of prothrombin converting activity

Hemker, H. C., Esnouf, M. P., Hemker, P. W., Swart, A. C. W. & MacFarlane, R. G., 1 Jan 1967, In : Nature. 215, 5098, p. 248-251 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Kinetic aspects of the interaction of blood-clotting enzymes: II. The relation between clotting time and plasma concentration in prothrombin-time estimations

Hemker, H. C., Siepel, T., Altman, R. & Loeliger, E. A., 1 Jan 1967, In : Thrombosis et diathesis haemorrhagica. 17, 3-4, p. 349-357 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

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Reaction sequence of blood coagulation

Hemker, H. C. & Kahn, M. J. P., 1 Jan 1967, In : Nature. 215, p. 1201-1202 2 p.

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The pathways of blood coagulation

Hemker, H. C., 1 Jan 1967, In : Folia medica neerlandica. 10, 4/5, p. 101-111 11 p.

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Treatment of haemophilia A with purified factor VIII obtained from human plasma by cryoprecipitation

Meyer, K., Eernisse, J. G., Veltkamp, J. J., Hemker, H. C. & Loeliger, E. A., 1 Jan 1967, In : Folia medica neerlandica. 10, 2, p. 49-60 12 p.

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Treatment of Haemophilia B with purified factor IX (PPSB)

Loeliger, E. A., Hensen, A., Mattern, M. J., Veltkamp, J. J., Bruning, P. F. & Hemker, H. C., 1 Jan 1967, In : Folia medica neerlandica. 10, 4, p. 112-125 14 p.

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1968

Arvin: Een nieuw anticoagulans

Hemker, H. C. & Loeliger, E. A., 1968, In : Nederlands Tijdschrift voor Geneeskunde. 112, 43, p. 1958-1960 3 p.

Research output: Contribution to journalArticleAcademic

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Behandlung der Hämophilie B mit PPSB

Loeliger, E. A., Mattern, M. J., Hensen, A. & Hemker, H. C., Feb 1968, In : Blut. 16, p. 289-297 9 p.

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Kinetic aspects of the interaction of blood clotting enzymes: IV. Kinetics of competitive inhibition in clotting tests

Hemker, H. C. & Hemker, P. W., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 19, 3-4, p. 364-367 4 p.

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Kinetic aspects of the interaction of blood clotting enzymes: III. Demonstration of an inhibitor of prothrombin conversion in vitamin K deficiency

Hemker, H. C., Veltkamp, J. J. & Loeliger, E. A., 1 Jan 1968, In : Thrombosis et diathesis haemorrhagica. 19, 3-4, p. 346-363 18 p.

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Principles of the mode of action of coumarin congeners

Loeliger, E. A. & Hemker, H. C., 1 Jan 1968, Proceedings of the 3rd International Pharmacological Meeting: July 24-30, 1966. 1 ed. Oxford: Pergamon Press Ltd., Vol. 6. p. 13-24 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Protrombinetijden en Thrombotest bij antistollingsbehandeling

Loeliger, E. A. & Hemker, H. C., 30 Nov 1968, In : Nederlands Tijdschrift voor Geneeskunde. 112, 48, p. 2195-2198 4 p.

Research output: Contribution to journalArticleAcademic

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1969

Considerations on an international standard for the one-stage prothrombin time in the control of anticoagulant therapy

Loeliger, E. A. & Hemker, H. C., 1969, Plasma Fractions for the Treatment of Hemophilia: Anticoagulant Therapy: Standardization of Tests; Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis, Washington, D.C., U.S.A., December 1967. Brinkhous, K. M. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 101-105 5 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Disturbances of blood clotting mechanism induced by antimetabolites of vitamin K

Hemker, H. C., van der Meer, J., Hodge, R. & Loeliger, E. A., 1969, Vitamine A, E und K: Klinische und physiologisch-chemische Probleme: Symposion, veranstaltet von der I. Medizinschen Klinik der Freien Universität Berlin vom 7.-8. September 1967. von Kress, H. F. & Blum, K-U. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 199-217 19 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Het reactiemechanisme van de bloedstolling

Hemker, H. C. & Haanen, C., Feb 1969, In : Nederlands Tijdschrift voor Geneeskunde. 113, 5, p. 203-210 8 p.

Research output: Contribution to journalArticleAcademic

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Studies on blood coagulation factor V: I. The interaction of salts of fatty acids and coagulation factors

Kahn, M. J. P. & Hemker, H. C., 1969, In : Thrombosis et diathesis haemorrhagica. 12, 3, p. 417-430 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

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The kinetics of enzyme cascade systems: General kinetics of enzyme cascades

Hemker, H. C. & Hemker, P. W., 1 Jan 1969, In : Proceedings of the Royal Society of London, Series B, Biological sciences. 173, 1032, p. 411-420 10 p., H.

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1970

Factor IX concentrate: Preparation by a simple method and clinical use

Bruning, P. F., Swart, A. C. W., Veltkamp, J. J., Hemker, H. C. & Loeliger, E. A., 1970, Hemophilia and New Hemorrhagic States: International Symposium, New York, Proceedings. Brinkhous, K. M. (ed.). 1 ed. University of North Carolina Press, p. 3-13 11 p.

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Laboratory control of oral anticoagulants: Definition of therapeutic range in terms of different thromboplastin preparations

Loeliger, E. A., Meuwisse-Braun, J. B., Muis, H., Buitendijk, F. J. J., Veltkamp, J. J. & Hemker, H. C., 30 Jun 1970, In : Thrombosis et diathesis haemorrhagica. 23, 3, p. 569-584 16 p.

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Les protéines dont la synthèse est induite par l'avitaminose K

Hemker, H. C., 1 Jan 1970, In : Nouvelle revue francaise d'hematologie. 10, 5, p. 645-652 8 p.

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Separation of blood coagulation factors II, VII, IX and X by cel filtration in the presence of Dextran blue

Swart, A. C. W. & Hemker, H. C., 29 Dec 1970, In : Biochimica et Biophysica Acta-general Subjects. 222, 3, p. 692-695 4 p.

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Standardization in the laboratory control of oral anticoagulants

Loeliger, E. A. & Hemker, H. C., 1970, Vascular Factors and Thrombosis: Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis Bath, England, October 1969. Koller, F., Brinkhous, K. M., Biggs, R., Rodman, N. F. & Hinnom, S. (eds.). 1 ed. Stuttgart: F. K. Schattauer Verlag, p. 359-370 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Standardization of results obtained with different thromboplastin preparations

Loeliger, E. A., Taconis, W. K., Veltkamp, J. J. & Hemker, H. C., 1970, Fibrinogen: Structural, Metabolic and Patophysiologic Aspects: Transactions of the Conference Held Under the Auspices of the International Committee on Haemostasis and Thrombosis, Princeton, New Jersey, U.S.A., November 24-26, 1968. Brinkhous, K. M. (ed.). Stuttgart: F. K. Schattauer Verlag, p. 369-376 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingAcademicpeer-review

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Studies on blood coagulation factor V: IV. A partially purified factor V preparation from human plasma

Kahn, M. J. P. & Hemker, H. C., 1970, In : Coagulation. 3, 1, p. 63-66 4 p.

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Studies on blood coagulation factor V: II. Preparation and properties of an artificial factor V reagent by adsorption with Ba-stearate

Kahn, M. J. P. & Hemker, H. C., 1970, In : Coagulation. 3, 1, p. 55-58 4 p.

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Studies on blood coagulation factor V: III. Kinetics of the estimation of factor V

Kahn, M. J. P. & Hemker, H. C., 1970, In : Coagulation. 3, 1, p. 59-62 4 p.

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The adsorption of coagulation factors onto phospholipids: Its role in the reaction mechanism of blood coagulation

Hemker, H. C., Kahn, M. P. J. & Devilee, P. P., 31 Oct 1970, In : Thrombosis et diathesis haemorrhagica. 24, 1-2, p. 214-223 10 p.

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Twee typen protrombine bij vitamine-K-deficiëntie

Hemker, H. C., Muller, A. D. & Loeliger, E. A., 26 Dec 1970, In : Nederlands Tijdschrift voor Geneeskunde. 114, 52, p. 2197-2198 2 p.

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