Abstract
PURPOSE: To assess the primary safety and oncological outcome of percutaneous cryoablation in patients with non-visceral metastases of the abdominal cavity after prior surgery.
METHODS: All patients with non-visceral metastases after prior abdominal surgery, treated with percutaneous cryoablation, and at least one year of follow-up were retrospectively identified. Technical success was achieved if the ice-ball had a minimum margin of 10 mm in three dimensions on the per-procedural CT images. Complications were recorded using the Society of Interventional Radiology (SIR) classification system. Time until disease progression was monitored with follow-up CT and/or MRI. Local control was defined as absence of recurrence at the site of ablation.
RESULTS: Eleven patients underwent cryoablation for 14 non-visceral metastases (mean diameter 20 ± 9 mm). Primary tumor origin was renal cell (n = 4), colorectal (n = 3), granulosa cell (n = 2), endometrium (n = 1) and appendix (n = 1) carcinoma. Treated metastases were localized retroperitoneal (n = 8), intraperitoneal (n = 2), or in the abdominal wall (n = 4). Technical success was achieved in all procedures. After a median follow-up of 27 months (12-38 months), all patients were alive. Local control was observed in 10/14 non-visceral metastases, and the earliest local progression was detected after ten months. No major adverse events occurred. One patient suffered a minor asymptomatic adverse event.
CONCLUSION: This proof-of-concept study suggests that cryoablation can be a minimal invasive treatment option in a selected group of patients with non-visceral metastases in the abdominal cavity after prior surgery.
Original language | English |
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Pages (from-to) | 3345-3352 |
Number of pages | 8 |
Journal | Abdominal Radiology |
Volume | 47 |
Issue number | 9 |
Early online date | 2 Jul 2022 |
DOIs | |
Publication status | Published - Sept 2022 |
Keywords
- Abdomen
- COLORECTAL-CANCER
- Cryosurgery
- FEASIBILITY
- GUIDED CRYOABLATION
- Interventional Radiology
- Metastases
- Neoplasms
- OUTCOMES
- RECURRENCE
- RENAL-CELL CARCINOMA
- RESECTION
- SURVEILLANCE