3D additive manufactured composite scaffolds with antibiotic-loaded lamellar fillers for bone infection prevention and tissue regeneration

M. Camara-Torres, S. Duarte, R. Sinha, A. Egizabal, N. Alvarez, M. Bastianini, M. Sisani, P. Scopece, M. Scatto, A. Bonetto, A. Marcomini, A. Sanchez, A. Patelli, C. Mota, L. Moroni

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)1073-1082
Number of pages10
JournalBioactive Materials
Volume6
Issue number4
DOIs
Publication statusPublished - 1 Apr 2021

Keywords

  • antibiotic delivery
  • antimicrobial activity
  • block-copolymers
  • bone infection
  • bone regeneration
  • ciprofloxacin
  • drug-delivery
  • human mesenchymal stromal cells
  • in-vitro release
  • intercalation
  • lamellar inorganic fillers
  • layered double hydroxide
  • melt extrusion additive manufacturing
  • osteoblast proliferation
  • sustained-release
  • zirconium-phosphate
  • BLOCK-COPOLYMERS
  • Lamellar inorganic fillers
  • Bone regeneration
  • DRUG-DELIVERY
  • ZIRCONIUM-PHOSPHATE
  • Antibiotic delivery
  • LAYERED DOUBLE HYDROXIDE
  • Bone infection
  • SUSTAINED-RELEASE
  • CIPROFLOXACIN
  • Melt extrusion additive manufacturing
  • IN-VITRO RELEASE
  • OSTEOBLAST PROLIFERATION
  • INTERCALATION
  • Human mesenchymal stromal cells
  • ANTIMICROBIAL ACTIVITY

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