Abstract
Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation therapy that has become a method of choice for the treatment of several neuropsychiatric disorders such as depression and OCD. It is considered to be a safe and well-tolerated treatment, with only few side effects. The most serious adverse event during any rTMS treatment is the potential induction of a seizure. rTMS has shown very encouraging results for treatment-resistant OCD, although the optimal target area and the stimulation frequency are still matters of controversy. Here, we present a 19-year-old female patient with OCD who experienced seizure during the 7th session of her rTMS treatment using the FDA-approved 20-Hz protocol for OCD applied bilaterally over the left and right DMPFC using a double-cone coil. Nonetheless, it still unknown whether the seizure occurred as a consequence of rTMS, as the patient was also in a specific seizure risk group. Future reviews are needed to further clarify the mechanisms that may trigger seizures during rTMS treatments in order to reduce the likelihood of rTMS-induced seizures.
Original language | English |
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Pages (from-to) | 584-590 |
Number of pages | 7 |
Journal | Case Reports in Neurology |
Volume | 13 |
Issue number | 3 |
DOIs | |
Publication status | Published - 28 Oct 2021 |
Keywords
- DOUBLE-BLIND
- Deep brain stimulation
- Dorsomedial prefrontal cortex
- High-frequency repetitive transcranial magnetic stimulation
- METAANALYSIS
- OBSESSIVE-COMPULSIVE DISORDER
- Obsessive-compulsive disorder
- RTMS
- Repetitive transcranial magnetic stimulation
- SAFETY
- SYNCOPE
- Seizure induction
- TRANSCRANIAL MAGNETIC STIMULATION
- Transcranial magnetic stimulation-induced seizure