1.14 Calcium Phosphates and Bone Induction ☆

H. Yuan; D. Barbieri; X. Luo; C.a. Van Blitterswijk; J.d. De Bruijn

doi:10.1016/B978-0-12-803581-8.10241-3

1.14 Calcium Phosphates and Bone Induction ☆

H. Yuan, D. Barbieri, X. Luo, C.a. Van Blitterswijk, J.d. De Bruijn

Research output: Chapter in Book/Report/Conference proceeding › Chapter › Academic

Abstract

Calcium phosphates (caps) have a widespread use in bone repair and regeneration due to their osteoconductive and bioactive (bone bonding) nature. In the past decade, it has become apparent that a sub-group of caps with specific physico-chemical properties have the ability to induce bone formation in ectopic sites (ie, intramuscular or sub-cutaneously). In this chapter, we summarize the scientific evidence of cap induced bone formation, describe material properties required for bone induction and discuss possible underlying mechanisms. In addition, we also provide data on the clinical efficacy of this unique group of caps.

Original language	English
Title of host publication	Comprehensive Biomaterials II
Publisher	Elsevier
Chapter	1.14
Pages	333-349
Number of pages	17
ISBN (Print)	9780081006924
DOIs	https://doi.org/10.1016/B978-0-12-803581-8.10241-3
Publication status	Published - 2017

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10.1016/B978-0-12-803581-8.10241-3

http://linkinghub.elsevier.com/retrieve/pii/B9780128035818102413

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abstract = "Calcium phosphates (caps) have a widespread use in bone repair and regeneration due to their osteoconductive and bioactive (bone bonding) nature. In the past decade, it has become apparent that a sub-group of caps with specific physico-chemical properties have the ability to induce bone formation in ectopic sites (ie, intramuscular or sub-cutaneously). In this chapter, we summarize the scientific evidence of cap induced bone formation, describe material properties required for bone induction and discuss possible underlying mechanisms. In addition, we also provide data on the clinical efficacy of this unique group of caps.",

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AU - Barbieri, D.

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AU - De Bruijn, J.d.

PY - 2017

Y1 - 2017

N2 - Calcium phosphates (caps) have a widespread use in bone repair and regeneration due to their osteoconductive and bioactive (bone bonding) nature. In the past decade, it has become apparent that a sub-group of caps with specific physico-chemical properties have the ability to induce bone formation in ectopic sites (ie, intramuscular or sub-cutaneously). In this chapter, we summarize the scientific evidence of cap induced bone formation, describe material properties required for bone induction and discuss possible underlying mechanisms. In addition, we also provide data on the clinical efficacy of this unique group of caps.

AB - Calcium phosphates (caps) have a widespread use in bone repair and regeneration due to their osteoconductive and bioactive (bone bonding) nature. In the past decade, it has become apparent that a sub-group of caps with specific physico-chemical properties have the ability to induce bone formation in ectopic sites (ie, intramuscular or sub-cutaneously). In this chapter, we summarize the scientific evidence of cap induced bone formation, describe material properties required for bone induction and discuss possible underlying mechanisms. In addition, we also provide data on the clinical efficacy of this unique group of caps.

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DO - 10.1016/B978-0-12-803581-8.10241-3

M3 - Chapter

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SP - 333

EP - 349

BT - Comprehensive Biomaterials II

PB - Elsevier

ER -

1.14 Calcium Phosphates and Bone Induction ☆

Abstract

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