Ethics of ECPR research

Martje M Suverein; David Shaw; Roberto Lorusso; Thijs S R Delnoij; Brigitte Essers; Patrick W Weerwind; David Townend; Marcel C G van de Poll; Jos G Maessen

doi:10.1016/j.resuscitation.2021.08.007

Ethics of ECPR research

Martje M Suverein^*, David Shaw, Roberto Lorusso, Thijs S R Delnoij, Brigitte Essers, Patrick W Weerwind, David Townend, Marcel C G van de Poll, Jos G Maessen

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

The design of emergency medicine trials can raise several ethical concerns - risks may be greater, and randomisation may have to occur before consent. Research in emergency medicine is thus an illuminating context to explore the interplay between risk and randomisation, and the consequences for consent. Using a currently running trial, we describe possible concerns, considerations, and solutions to reconcile the conflicting interests of scientific inquiry, ethical principles, and clinical reality in emergency medicine research.

Original language	English
Pages (from-to)	136-142
Number of pages	7
Journal	Resuscitation
Volume	169
DOIs	https://doi.org/10.1016/j.resuscitation.2021.08.007
Publication status	Published - Dec 2021

Keywords

Cardiopulmonary Resuscitation
Emergency Medicine
Extracorporeal Membrane Oxygenation
Humans
Out-of-Hospital Cardiac Arrest

Access to Document

10.1016/j.resuscitation.2021.08.007Licence: CC BY

Cite this

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title = "Ethics of ECPR research",

abstract = "The design of emergency medicine trials can raise several ethical concerns - risks may be greater, and randomisation may have to occur before consent. Research in emergency medicine is thus an illuminating context to explore the interplay between risk and randomisation, and the consequences for consent. Using a currently running trial, we describe possible concerns, considerations, and solutions to reconcile the conflicting interests of scientific inquiry, ethical principles, and clinical reality in emergency medicine research.",

keywords = "Cardiopulmonary Resuscitation, Emergency Medicine, Extracorporeal Membrane Oxygenation, Humans, Out-of-Hospital Cardiac Arrest",

author = "Suverein, {Martje M} and David Shaw and Roberto Lorusso and Delnoij, {Thijs S R} and Brigitte Essers and Weerwind, {Patrick W} and David Townend and {van de Poll}, {Marcel C G} and Maessen, {Jos G}",

year = "2021",

month = dec,

doi = "10.1016/j.resuscitation.2021.08.007",

language = "English",

volume = "169",

pages = "136--142",

journal = "Resuscitation",

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T1 - Ethics of ECPR research

AU - Suverein, Martje M

AU - Shaw, David

AU - Lorusso, Roberto

AU - Delnoij, Thijs S R

AU - Essers, Brigitte

AU - Weerwind, Patrick W

AU - Townend, David

AU - van de Poll, Marcel C G

AU - Maessen, Jos G

PY - 2021/12

Y1 - 2021/12

N2 - The design of emergency medicine trials can raise several ethical concerns - risks may be greater, and randomisation may have to occur before consent. Research in emergency medicine is thus an illuminating context to explore the interplay between risk and randomisation, and the consequences for consent. Using a currently running trial, we describe possible concerns, considerations, and solutions to reconcile the conflicting interests of scientific inquiry, ethical principles, and clinical reality in emergency medicine research.

AB - The design of emergency medicine trials can raise several ethical concerns - risks may be greater, and randomisation may have to occur before consent. Research in emergency medicine is thus an illuminating context to explore the interplay between risk and randomisation, and the consequences for consent. Using a currently running trial, we describe possible concerns, considerations, and solutions to reconcile the conflicting interests of scientific inquiry, ethical principles, and clinical reality in emergency medicine research.

KW - Cardiopulmonary Resuscitation

KW - Emergency Medicine

KW - Extracorporeal Membrane Oxygenation

KW - Humans

KW - Out-of-Hospital Cardiac Arrest

U2 - 10.1016/j.resuscitation.2021.08.007

DO - 10.1016/j.resuscitation.2021.08.007

M3 - (Systematic) Review article

C2 - 34411691

SN - 0300-9572

VL - 169

SP - 136

EP - 142

JO - Resuscitation

JF - Resuscitation

ER -