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Research Output

2005

Acute and separate modulation of motor and cognitive performance in parkinsonian rats by bilateral stimulation of the subthalamic nucleus.

Temel, Y., Visser-Vandewalle, V., Aendekerk, B., Rutten, B. P. F., Tan, S. K. H., Scholtissen, B., Schmitz, C., Blokland, A. & Steinbusch, H. W. M., 1 Jan 2005, In : Experimental Neurology. 193, 1, p. 43-52

Research output: Contribution to journalArticleAcademicpeer-review

74 Citations (Scopus)

The functional role of the subthalamic nucleus in cognitive and limbic circuits

Temel, Y., Blokland, A., Steinbusch, H. W. M. & Visser-Vandewalle, V., 1 Jan 2005, In : Progress in Neurobiology. 76, 6, p. 393-413

Research output: Contribution to journalArticleAcademicpeer-review

216 Citations (Scopus)
2006

Differential effects of subthalamic nucleus stimulation in advanced Parkinson disease on reaction time performance.

Temel, Y., Blokland, A., Ackermans, L., Boon, P., van Kranen-Mastenbroek, V. H. J. M., Beuls, E. A., Spincemaille, G. H. J. J. & Visser-Vandewalle, V., 1 Jan 2006, In : Experimental Brain Research. 169, 3, p. 389-399

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Motor and cognitive improvement by deep brain stimulation in a transgenic rat model of Huntington's disease

Temel, Y., Cao, C., Vlamings, R., Blokland, A., Ozen, H., Steinbusch, H. W., Michelsen, K. A., von Horsten, S., Schmitz, C. & Vandewalle, V., 1 Jan 2006, In : Neuroscience Letters. 406, p. 138-141

Research output: Contribution to journalArticleAcademicpeer-review

41 Citations (Scopus)

Progressive deterioration of reaction time performance and choreiform symptoms in a new Huntington's disease transgenic ratmodel

Cao, C., Temel, Y., Blokland, A., Ozen, H., Steinbusch, H. W. M., Vlamings, R., Nguyen, H. P., von Horsten, S., Schmitz, C. & Visser-Vandewalle, V., 1 Jan 2006, In : Behavioural Brain Research. 170, 2, p. 257-261

Research output: Contribution to journalArticleAcademicpeer-review

39 Citations (Scopus)

Protection of nigral cell death by bilateral subthalamic nucleus stimulation

Temel, Y., Visser-Vandewalle, V., Kaplan, S., Kozan, R., Daemen, M. A. R. C., Blokland, A., Schmitz, C. & Steinbusch, H. W., 1 Jan 2006, In : Brain Research. 1120, 1, p. 100-105

Research output: Contribution to journalArticleAcademicpeer-review

68 Citations (Scopus)

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

Kantor, O., Temel, Y., Holzmann, C., Raber, K., Nguyen, H. P., Cao, C., Turkoglu, H. O., Rutten, B. P., Visser-Vandewalle, V., Steinbusch, H. W., Blokland, A., Korr, H., Riess, O., von Horsten, S. & Schmitz, C., 1 Jan 2006, In : Neurobiology of Disease. 22, p. 538-547

Research output: Contribution to journalArticleAcademicpeer-review

53 Citations (Scopus)

The subthalamic nucleus: From response selection to execution

Tan, S. K., Temel, Y., Blokland, A., Steinbusch, H. W. & Vandewalle, V., 1 Jan 2006, In : Journal of Chemical Neuroanatomy. 31, p. 155-161

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
2007

Hypomobility after DOI administration can be reversed by subthalamic nucleus deep brain stimulation

Hameleers, R., Blokland, A., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., 1 Jan 2007, In : Behavioural Brain Research. 185 (1), p. 65-7

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Inhibition of 5-HT neuron activity and induction of depressive-like behavior by high-frequency stimulation of the subthalamic nucleus

Temel, Y., Boothman, L. J., Blokland, A., Magill, P. J., Steinbusch, H. W. M., Visser-Vandewalle, V. & Sharp, T., 1 Jan 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 43, p. 17087-17092

Research output: Contribution to journalArticleAcademicpeer-review

124 Citations (Scopus)

The subthalamic nucleus : a novel motor-associative-limbic interface

Temel, Y., 1 Jan 2007, Maastricht: Universiteit Maastricht. 179 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
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199 Downloads (Pure)
2008

Buspirone induced acute and chronic changes of neural activation in the periaqueductal gray of rats

Lim, L. W., Temel, Y., Sesia, T. J. J., Vlamings, R., Visser-Vandewalle, V. E. R. M., Steinbusch, H. P. & Blokland, A., 1 Jan 2008, In : Neuroscience. 155, 1, p. 164-173

Research output: Contribution to journalArticleAcademicpeer-review

16 Citations (Scopus)

Deep brain stimulation of the nucleus accumbens core and shell: Opposite effects on impulsive action

Sesia, T. J. J., Temel, Y., Lim, L. W., Blokland, A., Steinbusch, H. P. & Visser-Vandewalle, V. E. R. M., 1 Jan 2008, In : Experimental Neurology. 214, 1, p. 135-139

Research output: Contribution to journalArticleAcademicpeer-review

32 Citations (Scopus)

Effect of buspirone on the behavioral regulation of rats in low versus high anxiety conditions

Lim, L. W., Temel, Y., Visser-Vandewalle, V. E. R. M., Steinbusch, H. P. J., Schruers, K. R. J., Hameleers, R., Esquivel, G., Griez, E. J. L. & Blokland, A., 1 Jan 2008, In : Arzneimittelforschung : Drug Research. 58, 6, p. 269-276

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

High-frequency stimulation of the dorsolateral periaqueductal gray and ventromedial hypothalamus fails to inhibit panic-like behaviour

Lim, L. W., Blokland, A., Visser-Vandewalle, V. E. R. M., Vlamings, R., Sesia, T. J. J., Steinbusch, H. P. J., Schruers, K. R. J., Griez, E. J. L. & Temel, Y., 1 Jan 2008, In : Behavioural Brain Research. 193, 2, p. 197-203

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)
2009

Fos immunoreactivity in the rat forebrain induced by electrical stimulation of the dorsolateral periaqueductal gray matter

Lim, L. W., Temel, Y., Visser-Vandewalle, V. E. R. M., Blokland, A. & Steinbusch, H. W. M., 1 Jan 2009, In : Journal of Chemical Neuroanatomy. 38, 2, p. 83-96

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)
2010

Attenuation of fear-like response by escitalopram treatment after electrical stimulation of the midbrain dorsolateral periaqueductal gray

Lim, L. W., Blokland, A., Tan, S., Vlamings, R., Sesia, T., Aziz-Mohammadi, M., Visser-Vandewalle, V., Steinbusch, H. W. M., Schruers, K. & Temel, Y., Dec 2010, In : Experimental Neurology. 226, 2, p. 293-300

Research output: Contribution to journalArticleAcademicpeer-review

Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats

Jahanshahi, A., Lim, L. W., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., 5 Apr 2010, In : Neuroscience Letters. 473, 2, p. 136-140

Research output: Contribution to journalArticleAcademicpeer-review

Deep brain stimulation of the nucleus accumbens shell increases impulsive behavior and tissue levels of dopamine and serotonin

Sesia, T., Bulthuis, V., Tan, S. K. H., Lim, L. W., Vlamings, R., Blokland, A., Steinbusch, H. W. M., Sharp, T., Visser-Vandewalle, V. E. R. M. & Temel, Y., Oct 2010, In : Experimental Neurology. 225, 2, p. 302-309 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)

Experimental Deep Brain Stimulation in Animal Models

Tan, S. K. H., Vlamings, R., Lim, L., Sesia, T., Janssen, M. L. F., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., Oct 2010, In : Neurosurgery. 67, 4, p. 1073-1080

Research output: Contribution to journalArticleAcademicpeer-review

Hyperdopaminergic Status in Experimental Huntington Disease

Jahanshahi, A., Vlamings, R., Kaya, A. H., Lim, L. W., Janssen, M. L. F., Tan, S., Visser-Vandewalle, V., Steinbusch, H. W. M. & Temel, Y., Sep 2010, In : Journal of Neuropathology and Experimental Neurology. 69, 9, p. 910-917

Research output: Contribution to journalArticleAcademicpeer-review

In vivo electroporation of the central nervous system: A non-viral approach for targeted gene delivery

De Vry, J., Martinez-Martinez, P., Losen, M., Temel, Y., Steckler, T., Steinbusch, H. W. M., De Baets, M. H. & Prickaerts, J., Nov 2010, In : Progress in Neurobiology. 92, 3, p. 227-244

Research output: Contribution to journalArticleAcademicpeer-review

LIMBIC EFFECTS OF HIGH-FREQUENCY STIMULATION OF THE SUBTHALAMIC NUCLEUS

Temel, Y., 2010, HORMONES OF THE LIMBIC SYSTEM. Vol. 82. p. 47-63 (Vitamins and Hormones).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Long-term outcome of thalamic deep brain stimulation in two patients with Tourette syndrome

Ackermans, L., Duits, A., Temel, Y., Winogrodzka, A., Peeters, F. P. M. L., Beuls, E. A. M. & Visser-Vandewalle, V., Oct 2010, In : Journal of Neurology Neurosurgery and Psychiatry. 81, 10, p. 1068-1072

Research output: Contribution to journalArticleAcademicpeer-review

Low Current-driven Micro-electroporation Allows Efficient In Vivo Delivery of Nonviral DNA into the Adult Mouse Brain

De Vry, J., Martinez-Martinez, P., Losen, M., Bode, G. H., Temel, Y., Steckler, T., Steinbusch, H. W. M., De Baets, M. & Prickaerts, J., Jun 2010, In : Molecular Therapy. 18, 6, p. 1183-1191

Research output: Contribution to journalArticleAcademicpeer-review

Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review

Andrade, P., Noblesse, L. H. M., Temel, Y., Ackermans, L., Lim, L. W., Steinbusch, H. W. M. & Visser-Vandewalle, V., Apr 2010, In : Acta Neurochirurgica. 152, 4, p. 565-577

Research output: Contribution to journalArticleAcademicpeer-review

Nucleus accumbens and impulsivity

Basar, K., Sesia, T., Groenewegen, H., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., Dec 2010, In : Progress in Neurobiology. 92, 4, p. 533-557

Research output: Contribution to journalArticleAcademicpeer-review

2011

Altered expression of neuronal tryptophan hydroxylase-2 mRNA in the dorsal and median raphe nuclei of three genetically modified mouse models relevant to depression and anxiety

Jahanshahi, A., Le Maitre, E., Temel, Y., Lanfumey, L., Hamon, M., Lesch, K-P., Tordera, R. M., Del Rio, J., Aso, E., Maldonado, R., Hoekfelt, T. & Steinbusch, H. W. M., Jul 2011, In : Journal of Chemical Neuroanatomy. 41, 4, p. 227-233

Research output: Contribution to journalArticleAcademicpeer-review

Cerebellar nuclei are activated by high-frequency stimulation of the subthalamic nucleus

Moers-Hornikx, V. M. P., Vles, J. S. H., Tan, S. K. H., Cox-Limpens, K. E. M., Hoogland, G., Steinbusch, W. M. H. & Temel, Y., 1 Jun 2011, In : Neuroscience Letters. 496, 2, p. 111-115

Research output: Contribution to journalArticleAcademicpeer-review

Close communication between the subependymal serotonergic plexus and the neurogenic subventricular zone

Jahanshahi, A., Temel, Y., Lim, L. W., Hoogland, G. & Steinbusch, H. W. M., Dec 2011, In : Journal of Chemical Neuroanatomy. 42, 4, p. 297-303

Research output: Contribution to journalArticleAcademicpeer-review

Corrigendum to “Attenuation of fear-like response by escitalopram treatment after electrical stimulation of the midbrain dorsolateral periaqueductal gray” [Exp Neurol. 226(2) (2010) 293–300]

Lim, L. W., Blokland, A., Tan, S. K. H., Vlamings, R., Sesia, T., Aziz-Mohammadi, M., Visser-Vandewalle, V., Steinbusch, H. W. M., Schruers, K. R. J. & Temel, Y., Feb 2011, In : Experimental Neurology. 227, 2, p. 328-329

Research output: Contribution to journalErratum / corrigendumAcademic

Double-blind clinical trial of thalamic stimulation in patients with Tourette syndrome

Ackermans, L., Duits, A., van der Linden, C., Tijssen, M. A., Schruers, K., Temel, Y., Kleijer, M., Nederveen, P., Bruggeman, R., Tromp, S., van Kranen-Mastenbroek, V., Kingma, H., Cath, D. C. & Visser-Vandewalle, V., Mar 2011, In : Brain. 134, p. 832-844

Research output: Contribution to journalArticleAcademicpeer-review

High frequency stimulation of the subthalamic nucleus increases c-fos immunoreactivity in the dorsal raphe nucleus and afferent brain regions

Tan, S. K. H., Janssen, M. L. F., Jahanshahi, A., Chouliaras, L., Visser-Vandewalle, V., Lim, L. W., Steinbusch, H. W. M., Sharp, T. & Temel, Y., Oct 2011, In : Journal of Psychiatric Research. 45, 10, p. 1307-1315

Research output: Contribution to journalArticleAcademicpeer-review

HIGH-FREQUENCY STIMULATION OF THE SUBTHALAMIC NUCLEUS INHIBITS THE FIRING OF JUXTACELLULAR LABELLED 5-HT-CONTAINING NEURONES

Hartung, H., Tan, S. K. H., Steinbusch, H. M. W., Temel, Y. & Sharp, T., 14 Jun 2011, In : Neuroscience. 186, p. 135-145

Research output: Contribution to journalArticleAcademicpeer-review

High-frequency stimulation of the ventrolateral thalamus regulates gene expression in hippocampus, motor cortex and caudate-putamen

Kadar, E., Lim, L. W., Carreras, G., Genis, D., Temel, Y. & Huguet, G., 19 May 2011, In : Brain Research. 1391, p. 1-13

Research output: Contribution to journalArticleAcademicpeer-review

Impulse control and related disorders in Parkinson's disease patients treated with bilateral subthalamic nucleus stimulation: A review

Broen, M., Duits, A., Visser-Vandewalle, V., Temel, Y. & Winogrodzka, A., Jul 2011, In : Parkinsonism & Related Disorders. 17, 6, p. 413-417

Research output: Contribution to journalArticleAcademicpeer-review

Periaqueductal Grey Stimulation Induced Panic-Like Behaviour Is Accompanied by Deactivation of the Deep Cerebellar Nuclei

Moers-Hornikx, V. M. P., Vles, J. S. H., Lim, L. W., Ayyildiz, M., Kaplan, S., Gavilanes, A. W. D., Hoogland, G., Steinbusch, H. W. M. & Temel, Y., Mar 2011, In : Cerebellum. 10, 1, p. 61-69

Research output: Contribution to journalArticleAcademicpeer-review

Serotonin-dependent depression in Parkinson's disease: A role for the subthalamic nucleus?

Tan, S. K. H., Hartung, H., Sharp, T. & Temel, Y., Sep 2011, In : Neuropharmacology. 61, 3, p. 387-399

Research output: Contribution to journalArticleAcademicpeer-review

2012

A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission

Tan, S. K. H., Hartung, H., Visser-Vandewalle, V., Steinbusch, H. W. M., Temel, Y. & Sharp, T., Jan 2012, In : Experimental Neurology. 233, 1, p. 145-153

Research output: Contribution to journalArticleAcademicpeer-review

Automated gait analysis in bilateral Parkinsonian rats and the role of L-DOPA therapy

Westin, J. E., Janssen, M. L. F., Sager, T. N. & Temel, Y., 15 Jan 2012, In : Behavioural Brain Research. 226, 2, p. 519-528

Research output: Contribution to journalArticleAcademicpeer-review

Deep Brain Stimulation for Psychiatric Disease: Contributions and Validity of Animal Models

Hamani, C. & Temel, Y., 11 Jul 2012, In : Science Translational Medicine. 4, 142, 142rv8.

Research output: Contribution to journalArticleAcademicpeer-review

Deep brain stimulation of the subthalamic nucleus in Parkinson's disease: similar improvements in saccadic and manual responses

Antoniades, C. A., Carpenter, R. H. S. & Temel, Y., 15 Feb 2012, In : Neuroreport. 23, 3, p. 179-183

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Lessons Learned from the Transgenic Huntington's Disease Rats

Vlamings, R., Zeef, D. H., Janssen, M. L. F., Oosterloo, M., Schaper, F., Jahanshahi, A. & Temel, Y., 2012, In : Neural Plasticity. 2012, p. 682712

Research output: Contribution to journalArticleAcademicpeer-review

Memory deficits in the transgenic rat model of Huntington's disease

Zeef, D. H., van Goethem, N. P., Vlamings, R., Schaper, F., Jahanshahi, A., Hescham, S., von Hoersten, S., Prickaerts, J. & Temel, Y., 1 Feb 2012, In : Behavioural Brain Research. 227, 1, p. 194-198

Research output: Contribution to journalArticleAcademicpeer-review

Metabolic and electrophysiological changes in the basal ganglia of transgenic Huntington's disease rats

Vlamings, R., Benazzouz, A., Chetrit, J., Janssen, M. L. F., Kozan, R., Visser-Vandewalle, V., Steinbusch, H. W. M., von Hoersten, S. & Temel, Y., Dec 2012, In : Neurobiology of Disease. 48, 3, p. 488-494

Research output: Contribution to journalArticleAcademicpeer-review

Mild dopaminergic lesions are accompanied by robust changes in subthalamic nucleus activity

Janssen, M. L. F., Zwartjes, D. G. M., Tan, S. K. H., Vlamings, R., Jahanshahi, A., Heida, T., Hoogland, G., Steinbusch, H. W. M., Visser-Vandewalle, V. & Temel, Y., 6 Feb 2012, In : Neuroscience Letters. 508, 2, p. 101-105

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Motor and non-motor behaviour in experimental Huntington's disease

Zeef, D. H., Vlamings, R., Lim, L. W., Tan, S., Janssen, M. L. F., Jahanshahi, A., Hoogland, G., Prickaerts, J., Steinbusch, H. W. M. & Temel, Y., 15 Jan 2012, In : Behavioural Brain Research. 226, 2, p. 435-439

Research output: Contribution to journalArticleAcademicpeer-review

Neuromodulation in Psychiatric Disorders

Temel, Y., Hescham, S. A., Jahanshahi, A., Janssen, M. L. F., Tan, S. K. H., van Overbeeke, J. J., Ackermans, L., Oosterloo, M., Duits, A., Leentjens, A. F. G. & Lim, L., 2012, EMERGING HORIZONS IN NEUROMODULATION: NEW FRONTIERS IN BRAIN AND SPINE STIMULATION. Vol. 107. p. 283-314 (International Review of Neurobiology).

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

Subthalamic neuronal responses to cortical stimulation

Janssen, M. L. F., Zwartjes, D. G. M., Temel, Y., van Kranen-Mastenbroek, V., Duits, A., Bour, L. J., Veltink, P. H., Heida, T. & Visser-Vandewalle, V., Mar 2012, In : Movement Disorders. 27, 3, p. 435-438

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Unchanged expression of the ceramide transfer protein in the acute 6-OHDA neurodegenerative model

Mencarelli, C., Bode, G. H., Vlamings, R., Janssen, M. L. F., Losen, M., De Baets, M. H., Steinbusch, H. W. M., Temel, Y. & Martinez-Martinez, P., 6 Jan 2012, In : Neuroscience Letters. 506, 1, p. 39-43

Research output: Contribution to journalArticleAcademicpeer-review