20102019

Research output per year

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Research Output

  • 27 Article
  • 3 Editorial
  • 2 Comment/Letter to the editor
  • 2 Review article

Acquired resistance to the Hedgehog pathway inhibitor vismodegib due to smoothened mutations in treatment of locally advanced basal cell carcinoma

Brinkhuizen, T., Reinders, M. G., van Geel, M., Hendriksen, A. J., Paulussen, A. D., Winnepenninckx, V. J., Keymeulen, K. B., Soetekouw, P. M. M. B., van Steensel, M. A. & Mosterd, K., 1 Jan 2014, In : Journal of the American Academy of Dermatology. 71, 5, p. 1005-1008

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

9 Citations (Scopus)
17 Citations (Scopus)

Biallelic inactivation of protoporphyrinogen oxidase and hydroxymethylbilane synthase is associated with liver cancer in acute porphyrias

Schneider-Yin, X., van Serooskerken, A-M. V. T., Siegesmund, M., Went, P., Barman-Aksoezen, J., Bladergroen, R. S., Komminoth, P., Cloots, R. H. E., Winnepenninckx, V. J., Hausen, A. Z., Weber, M., Driessen, A., Poblete-Gutierrez, P., Bauer, P., Schroeder, C., van Geel, M., Minder, E. I. & Frank, J., Mar 2015, In : Journal of Hepatology. 62, 3, p. 734-738

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
Open Access

Bowen's Disease: A Six-year Retrospective Study of Treatment with Emphasis on Resection Margins

Westers-Attema, A., van den Heijkant, F., Lohman, B. G. P. M., Nelemans, P. J., Winnepenninckx, V., Kelleners-Smeets, N. W. J. & Mosterd, K., 1 Jan 2014, In : Acta Dermato-Venereologica. 94, 4, p. 431-435

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Clustered unilateral trichoepitheliomas indicate Type 1 segmental manifestation of multiple familial trichoepithelioma

Parren, L. J. M. T., Munte, K., Winnepenninckx, V., van Geel, M., Steijlen, P. M., Frank, J. & van Steensel, M. A. M., Aug 2016, In : Clinical and Experimental Dermatology. 41, 6, p. 682-684

Research output: Contribution to journalEditorialAcademicpeer-review

Detection of Merkel Cell Polyomavirus in Seborrheic Keratosis

Hillen, L. M., Rennspiess, D., Speel, E-J., Haugg, A. M., Winnepenninckx, V. & Zur Hausen, A., 9 Jan 2018, In : Frontiers in microbiology. 8, 8 p., 2648.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Early B-Cell Differentiation in Merkel Cell Carcinomas: Clues to Cellular Ancestry

zur Hausen, A., Rennspiess, D., Winnepenninckx, V., Speel, E-J. & Kurz, A. K., 15 Aug 2013, In : Cancer Research. 73, 16, p. 4982-4987

Research output: Contribution to journalArticleAcademicpeer-review

Epigenetic Changes in Basal Cell Carcinoma Affect SHH and WNT Signaling Components

Brinkhuizen, T., van den Hurk, K., Winnepenninckx, V. J. L., de Hoon, J. P., van Marion, A. M. W., Veeck, J., van Engeland, M. & van Steensel, M. A. M., 17 Dec 2012, In : PLOS ONE. 7, 12, E51710.

Research output: Contribution to journalArticleAcademicpeer-review

Familial Pityriasis Rubra Pilaris Is Caused by Mutations in CARD14

Fuchs-Telem, D., Sarig, O., van Steensel, M. A. M., Isakov, O., Israeli, S., Nousbeck, J., Richard, K., Winnepenninckx, V., Vernooij, M., Shomron, N., Uitto, J., Fleckman, P., Richard, G. & Sprecher, E., 13 Jul 2012, In : American Journal of Human Genetics. 91, 1, p. 163-170

Research output: Contribution to journalArticleAcademicpeer-review

62 Citations (Scopus)

Frequent detection of human polyomavirus 6 in keratoacanthomas

Beckervordersandforth, J., Pujari, S., Rennspiess, D., Speel, E. J. M., Winnepenninckx, V., Diaz, C., Weyers, W., Haugg, A. M., Kurz, A. K. & zur Hausen, A., 7 Jul 2016, In : Diagnostic Pathology. 11, 58.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
4 Citations (Scopus)

Gene expression profiling of human angiotropic primary melanoma: Selection of 15 differentially expressed genes potentially involved in extravascular migratory metastasis

Lugassy, C., Lazar, V., Dessen, P., van den Oord, J. J., Winnepenninckx, V., Spatz, A., Bagot, M., Bensussan, A., Janin, A., Eggermont, A. M. & Barnhill, R. L., May 2011, In : European Journal of Cancer. 47, 8, p. 1267-1275

Research output: Contribution to journalArticleAcademicpeer-review

Genetics and epigenetics of cutaneous malignant melanoma: A concert out of tune

van den Hurk, K., Niessen, H. E. C., Veeck, J., van den Oord, J. J., van Steensel, M. A. M., zur Hausen, A., van Engeland, M. & Winnepenninckx, V. J. L., Aug 2012, In : Biochimica et Biophysica Acta-reviews on Cancer. 1826, 1, p. 89-102

Research output: Contribution to journalArticleAcademicpeer-review

Genomic Landscape of Spitzoid Neoplasms Impacting Patient Management

Hillen, L. M., Van den Oord, J., Geybels, M. S., Becker, J. C., zur Hausen, A. & Winnepenninckx, V., 13 Dec 2018, In : Frontiers in medicine. 5, 17 p., 344.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Id1 overexpression is independent of repression and epigenetic silencing of tumor suppressor genes in melanoma

Healey, M. A., Deaton, S. L., Alder, J. K., Winnepenninckx, V., Casero, R. A. . J. & Herman, J. G., 1 Jul 2010, In : Epigenetics. 5, 5, p. 410-421

Research output: Contribution to journalArticleAcademicpeer-review

Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma

Brinkhuizen, T., Weijzen, C. A. H., Eben, J., Thissen, M. R., van Marion, A. M., Lohman, B. G., Winnepenninckx, V. J. L., Nelemans, P. J. & van Steensel, M. A. M., 1 Jan 2014, In : PLOS ONE. 9, 9, e106427.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile

Brinkhuizen, T., van Geel, M., Denil, S. L. I. J., De Meyer, T., Kelleners-Smeets, N. W. J., Lohuis, P. J. F. M., Hoebers, F. J. P., Winnepenninckx, V. J. L., van Steensel, M. A. M. & Mosterd, K., Apr 2016, In : Experimental Dermatology. 25, 4, p. 316-318

Research output: Contribution to journalEditorialAcademicpeer-review

Loss of microRNA-200a and c, and microRNA-203 expression at the invasive front of primary cutaneous melanoma is associated with increased thickness and disease progression

van Kempen, L. C., van den Hurk, K., Lazar, V., Michiels, S., Winnepenninckx, V., Stas, M., Spatz, A. & van den Oord, J. J., Oct 2012, In : Virchows Archiv. 461, 4, p. 441-448

Research output: Contribution to journalArticleAcademicpeer-review

Molecular profiling of Spitz nevi identified by digital RNA counting

Hillen, L. M., Geybels, M. S., Rennspiess, D., Spassova, I., Ritter, C., Becker, J. C., Garmyn, M., zur Hausen, A., Van den Oord, J. & Winnepenninckx, V., Dec 2018, In : Melanoma Research. 28, 6, p. 510-520 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Neuroendocrine Key Regulator Gene Expression in Merkel Cell Carcinoma

Chteinberg, E., Sauer, C. M., Rennspiess, D., Beumers, L., Schiffelers, L., Eben, J., Haugg, A., Winnepenninckx, V., Kurz, A. K., Speel, E-J., Zenke, M. & zur Hausen, A., Dec 2018, In : Neoplasia (Online). 20, 12, p. 1227-1235 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Persistent exit-site "infection" in a peritoneal dialysis patient with chronic lymphocytic leukemia

Cornelis, T., van der Sande, F. M., Winnepenninckx, V., Kooman, J. P. & Peppelenbosch, A. G., 1 Jan 2012, In : Peritoneal Dialysis International. 32, 6, p. 671-672

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

PET imaging of zirconium-89 labelled cetuximab: A phase I trial in patients with head and neck and lung cancer

van Loon, J., Even, A. J. G., Aerts, H. J. W. L., Ollers, M., Hoebers, F., van Elmpt, W., Dubois, L., Dingemans, A-M. C., Lalisang, R. I., Kempers, P., Brans, B., Winnepenninckx, V., Speel, E-J., Thunnissen, E., Smits, K. M., Boellaard, R., Vugts, D. J., De Ruysscher, D. & Lambin, P., Feb 2017, In : Radiotherapy and Oncology. 122, 2, p. 267-273 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Phosphatidylinositol 3-kinase p110δ expression in Merkel cell carcinoma

Chteinberg, E., Rennspiess, D., Sambo, R., Tauchmann, S., Kelleners-Smeets, N. W. J., Winnepenninckx, V., Speel, E., Kurz, A. K., Zenke, M. & zur Hausen, A., 2018, In : Oncotarget. 9, 51, p. 29565-29573

Research output: Contribution to journalArticleAcademicpeer-review

Photodynamic Therapy in Bowen's Disease: Influence of Histological Features and Clinical Characteristics on Its Success

Westers-Attema, A., Lohman, B. G. P. M., van den Heijkant, F., Nelemans, P. J., Winnepenninckx, V. J., Kelleners-Smeets, N. W. J. & Mosterd, K., 1 Jan 2015, In : Dermatology. 230, 1, p. 55-61

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Prognostic Significance of Promoter Hypermethylation and Diminished Gene Expression of SYNPO2 in Melanoma

Gao, L., van den Hurk, K., Nsengimana, J., Laye, J. P., van den Oord, J. J., Beck, S., Gruis, N. A., Zoutman, W. H., van Engeland, M., Newton-Bishop, J. A., Winnepenninckx, V. J. & van Doorn, R., Sep 2015, In : Journal of Investigative Dermatology. 135, 9, p. 2328-2331

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Promoter CpG Island Hypermethylation in Dysplastic Nevus and Melanoma: CLDN11 as an Epigenetic Biomarker for Malignancy

Gao, L., van den Hurk, K., Moerkerk, P. T. M., Goeman, J. J., Beck, S., Gruis, N. A., van den Oord, J. J., Winnepenninckx, V. J., van Engeland, M. & van Doorn, R., Dec 2014, In : Journal of Investigative Dermatology. 134, 12, p. 2957-2966

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Quantitative assessment of Zirconium-89 labeled cetuximab using PET/CT imaging in patients with advanced head and neck cancer: a theragnostic approach

Even, A. J. G., Hamming-Vrieze, O., van Elmpt, W., Winnepenninckx, V. J. L., Heukelom, J., Tesselaar, M. E. T., Vogel, W. V., Hoeben, A., Zegers, C. M. L., Vugts, D. J., van Dongen, G. A. M. S., Bartelink, H., Mottaghy, F. M., Hoebers, F. & Lambin, P., 17 Jan 2017, In : Oncotarget. 8, 3, p. 3870-3880 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinoma

Sauer, C. M., Haugg, A. M., Chteinberg, E., Rennspiess, D., Winnepenninckx, V., Speel, E. -J., Becker, J. C., Kurz, A. K. & zur Hausen, A., Aug 2017, In : Critical Reviews in Oncology/Hematology. 116, p. 99-105 7 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas

Kusters-Vandevelde, H. V. N., Creytens, D., van Engen-van Grunsven, A. C. H., Jeunink, M., Winnepenninckx, V., Groenen, P. J. T. A., Küsters, B., Wesseling, P., Blokx, W. A. M. & Prinsen, C. F. M., 15 Jan 2016, In : Acta neuropathologica communications. 4, 5.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Subtyping Basal Cell Carcinoma by Clinical Diagnosis Versus Punch Biopsy

Roozeboom, M. H., Kreukels, H., Nelemans, P. J., Mosterd, K., Winnepenninckx, V. J. L., Abdul Hamid, M. A., de Haas, E. R. M. & Kelleners-Smeets, N. W. J., 1 Jan 2015, In : Acta Dermato-Venereologica. 95, 8, p. 996-998 3 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

The different faces of actinomycosis

Roozeboom, M. H., Westers-Attema, A., Winnepenninckx, V., Hurkens, K. P. G. M. & Kelleners-Smeets, N. W. J., Apr 2012, In : Clinical and Experimental Dermatology. 37, 3, p. 322-324

Research output: Contribution to journalArticleAcademicpeer-review

The effect of topical diclofenac 3% and calcitriol 3 mg/g on superficial basal cell carcinoma (sBCC) and nodular basal cell carcinoma (nBCC): A phase II, randomized controlled trial

Brinkhuizen, T., Frencken, K. J. A., Nelemans, P., Hoff, M. L. S., Kelleners-Smeets, N. W. J., zur Hausen, A., van der Horst, M. P. J., Rennspiess, D., Winnepenninckx, V. J. L., van Steensel, M. A. M. & Mosterd, K., Jul 2016, In : Journal of the American Academy of Dermatology. 75, 1, p. 126-134

Research output: Contribution to journalArticleAcademicpeer-review

Trends in the Incidence of Bowen Disease Based on a Single-Center Study in the Netherlands

Jansen, M. H. E., Ozhan-Hasan, H., Nelemans, P. J., Winnepenninckx, V. J. & Mosterd, K., Nov 2019, In : Dermatologic Surgery. 45, 11, p. 1353-1358 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Tumor thickness and adnexal extension of superficial basal cell carcinoma (sBCC) as determinants of treatment failure for methylaminolevulinate (MAL)-photodynamic therapy (PDT), imiquimod, and 5-fluorouracil (FU)

Roozeboom, M. H., van Kleef, L., Arits, A. H. M. M., Mosterd, K., Winnepenninckx, V. J. L., van Marion, A. M. W., Nelemans, P. J. & Kelleners-Smeets, N. W. J., 1 Jan 2015, In : Journal of the American Academy of Dermatology. 73, 1, p. 93-98

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)