20072019

Research output per year

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Research Output

  • 22 Article
  • 6 Review article
  • 2 Erratum / corrigendum
  • 1 Conference article in proceeding
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Article
2019

Building a Professional Identity and an Academic Career Track in Translational Medicine

van Dijk, S. J., Domenighetti, A. A., Gomez-Ospina, N., Hunter, P., Lindemans, C. A., Melotte, V., van Rossum, A. M. C. & Rosenblum, N. D., 3 Jul 2019, In : Frontiers in medicine. 6, 6 p., 151.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

KRAS status is related to histological phenotype in gastric cancer: results from a large multicentre study

Hewitt, L. C., Saito, Y., Wang, T., Matsuda, Y., Oosting, J., Silva, A. N. S., Slaney, H. L., Melotte, V., Hutchins, G., Tan, P., Yoshikawa, T., Arai, T. & Grabsch, H. I., Nov 2019, In : Gastric Cancer. 22, 6, p. 1193-1203 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Multitarget Stool DNA Test Performance in an Average-Risk Colorectal Cancer Screening Population

Bosch, L. J. W., Melotte, V., Mongera, S., Daenen, K. L. J., Coupe, V. M. H., van Turenhout, S. T., Stoop, E. M., de Wijkerslooth, T. R., Mulder, C. J. J., Rausch, C., Kuipers, E. J., Dekker, E., Domanico, M. J., Lidgard, G. P., Berger, B. M., van Engeland, M., Carvalho, B. & Meijer, G. A., Dec 2019, In : American Journal of Gastroenterology. 114, 12, p. 1909-1918 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Analysis of DNA methylation in cancer: location revisited

Koch, A., Joosten, S. C., Feng, Z., de Ruijter, T. C., Draht, M. X., Melotte, V., Smits, K. M., Veeck, J., Herman, J. G., Van Neste, L., Van Criekinge, W., De Meyer, T. & van Engeland, M., 1 Jul 2018, In : Nature Reviews Clinical Oncology. 15, 7, p. 459-466 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cost-effectiveness of High-performance Biomarker Tests vs Fecal Immunochemical Test for Noninvasive Colorectal Cancer Screening

Lansdorp-Vogelaar, I., Goede, S. L., Bosch, L. J. W., Melotte, V., Carvalho, B., van Engeland, M., Meijer, G. A., de Koning, H. J. & van Ballegooijen, M., 1 Apr 2018, In : Clinical gastroenterology and hepatology. 16, 4, p. 504-12 20 p.

Research output: Contribution to journalArticleAcademicpeer-review

Epstein-Barr virus and mismatch repair deficiency status differ between oesophageal and gastric cancer: A large multi-centre study

Hewitt, L. C., Inam, I. Z., Saito, Y., Yoshikawa, T., Quaas, A., Hoelscher, A., Bollschweiler, E., Fazzi, G. E., Melotte, V., Langley, R. E., Nankivell, M., Cunningham, D., Allum, W., Hutchins, G. G. & Grabsch, H. I., May 2018, In : European Journal of Cancer. 94, p. 104-114 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

A Four-Gene Promoter Methylation Marker Panel Consisting of GREM1, NEURL, LAD1, and NEFH Predicts Survival of Clear Cell Renal Cell Cancer Patients

van Vlodrop, I. J. H., Joosten, S. C., De Meyer, T., Smits, K. M., Van Neste, L., Melotte, V., Baldewijns, M. M. L. L., Schouten, L. J., van den Brandt, P. A., Jeschke, J., Yi, J. M., Schuebel, K. E., Ahuja, N., Herman, J. G., Aarts, M. J., Bosman, F. T., Van Criekinge, W. & van Engeland, M., 15 Apr 2017, In : Clinical Cancer Research. 23, 8, p. 2006-2018 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

NDRG4, an early detection marker for colorectal cancer, is specifically expressed in enteric neurons

Vaes, N., Lentjes, M. H. F. M., Gijbels, M. J., Rademakers, G., Daenen, K. L., Boesmans, W., Wouters, K. A. D., Geuzens, A., Qu, X., Steinbusch, H. P. J., Rutten, B. P. F., Baldwin, S. H., Sharkey, K. A., Hofstra, R. M. W., van Engeland, M., Vanden Berghe, P. & Melotte, V., Sep 2017, In : Neurogastroenterology and Motility. 29, 9, 10 p., 13095.

Research output: Contribution to journalArticleAcademicpeer-review

2016

Analysis of RET promoter CpG island methylation using methylation-specific PCR (MSP), pyrosequencing, and methylation-sensitive high-resolution melting (MS-HRM): impact on stage II colon cancer patient outcome

Draht, M. X. G., Smits, K. M., Jooste, V., Tournier, B., Vervoort, M., Ramaekers, C., Chapusot, C., Weijenberg, M. P., van Engeland, M. & Melotte, V., 26 Apr 2016, In : Clinical epigenetics. 8, 44.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)

The emerging role of GATA transcription factors in development and disease

Lentjes - Beer, M., Niessen, H. E. C., Akiyama, Y., De Bruine, A. P., Melotte, V. & Van Engeland, M., 8 Mar 2016, In : Expert Reviews in Molecular Medicine. 18, e3.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2 Citations (Scopus)
2015

KRAS, BRAF and gastric cancer

Hewitt, L. C., Hutchins, G. G., Melotte, V., Saito, Y. & Grabsch, H. I., Nov 2015, In : Translational Gastrointestinal Cancer . 4, 6, p. 429-447

Research output: Contribution to journalArticleAcademicpeer-review

Spectrin Repeat Containing Nuclear Envelope 1 and Forkhead Box Protein E1 Are Promising Markers for the Detection of Colorectal Cancer in Blood

Melotte, V., Yi, J. M., Lentjes, M. H. F. M., Smits, K. M., Van Neste, L., Niessen, H. E. C., Wouters, K. A. D., Louwagie, J., Schuebel, K. E., Herman, J. G., Baylin, S. B., van Criekinge, W., Meijer, G. A., Ahuja, N. & van Engeland, M., Feb 2015, In : Cancer prevention research. 8, 2, p. 157-164

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
2014

CHFR Promoter Methylation Indicates Poor Prognosis in Stage II Microsatellite Stable Colorectal Cancer

Cleven, A. H. G., Derks, S., Draht, M. X. G., Smits, K. M., Melotte, V., Van Neste, L., Tournier, B., Jooste, V., Chapusot, C., Weijenberg, M. P., Herman, J. G., de Bruine, A. P. & van Engeland, M., 15 Jun 2014, In : Clinical Cancer Research. 20, 12, p. 3261-3271

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine

Derks, S., Cleven, A. H. G., Melotte, V., Smits, K. M., Brandes, J. C., Azad, N., van Criekinge, W., de Bruine, A. P., Herman, J. G. & van Engeland, M., Mar 2014, In : Cancer and Metastasis Reviews. 33, 1, p. 161-171

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Epigenetics in radiotherapy: Where are we heading?

Smits, K. M., Melotte, V., Niessen, H. E. C., Dubois, L., Oberije, C., Troost, E. G. C., Starmans, M. H. W., Boutros, P. C., Vooijs, M., van Engeland, M. & Lambin, P., May 2014, In : Radiotherapy and Oncology. 111, 2, p. 168-177

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Promoter CpG island methylation of RET predicts poor prognosis in stage II colorectal cancer patients

Draht, M. X. G., Smits, K. M., Tournier, B., Jooste, V., Chapusot, C., Carvalho, B., Cleven, A. H. G., Derks, S., Wouters, K. A. D., Belt, E. J. T., Stockmann, H. B. A. C., Bril, H., Weijenberg, M. P., van den Brandt, P. A., de Bruïne, A. P., Herman, J. G., Meijer, G. A., Piard, F., Melotte, V. & van Engeland, M., 1 Jan 2014, In : Molecular oncology. 8, 3, p. 679-688

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)
2013

The CpG Island Methylator Phenotype: What's in a Name?

Hughes, L. A. E., Melotte, V., de Schrijver, J., de Maat, M., Smit, V. T. H. B. M., Bovee, J. V. M. G., French, P. J., van den Brandt, P. A., Schouten, L. J., de Meyer, T., van Criekinge, W., Ahuja, N., Herman, J. G., Weijenberg, M. P. & van Engeland, M., 1 Oct 2013, In : Cancer Research. 73, 19, p. 5858-5868

Research output: Contribution to journalArticleAcademicpeer-review

60 Citations (Scopus)
2012

DNA Methylation of Phosphatase and Actin Regulator 3 Detects Colorectal Cancer in Stool and Complements FIT.

Bosch, L. J., Oort, F. A., Neerincx, M., Khalid-de Bakker, C. A., Terhaar Sive - Droste, J. S., Melotte, V., Jonkers, D. M. A. E., Masclee, A. A. M., Mongera, S., Grooteclaes, M., Louwagie, J., van Criekinge, W., Coupe, V. M., Mulder, C. J., van Engeland, M., Carvalho, B. & Meijer, G. A., Mar 2012, In : Cancer prevention research. 5, 3, p. 464-472 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)

Promoter CpG island methylation markers in colorectal cancer: the road ahead

Draht, M. X. G., Riedl, R. G., Niessen, H., Carvalho, B., Meijer, G. A., Herman, J. G., van Engeland, M., Melotte, V. & Smits, K. M., Apr 2012, In : Epigenomics. 4, 2, p. 179-194

Research output: Contribution to journalArticleAcademicpeer-review

2010

The N-myc downstream regulated gene (NDRG) family: diverse functions, multiple applications

Melotte, V., Qu, X., Ongenaert, M., Van Criekinge, W., de Bruine, A. P., Baldwin, H. S. & van Engeland, M., Nov 2010, In : Faseb Journal. 24, 11, p. 4153-4166

Research output: Contribution to journalArticleAcademicpeer-review

2009

GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer

Hellebrekers, D. M., Lentjes, M. H., van den Bosch, S. M., Melotte, V., Wouters, K. A., Daenen, K. L., Smits, K. M., Akiyama, Y., Yuasa, Y., Sanduleanu, S., Khalid - de Bakker, C. A., Jonkers, D., Weijenberg, M. P., Louwagie, J., van Criekinge, W., Carvalho, B., Meijer, G. A., Baylin, S. B., Herman, J. G., de Bruine, A. P. & 1 others, van Engeland, M., 1 Jan 2009, In : Clinical Cancer Research. 15, 12, p. 3990-7

Research output: Contribution to journalArticleAcademicpeer-review

103 Citations (Scopus)

N-Myc downstream-regulated gene 4 (NDRG4): a candidate tumor suppressor gene and potential biomarker for colorectal cancer

Melotte, V., Lentjes, M. H., van den Bosch, S. M., Hellebrekers, D. M., de Hoon, J. P. J., Wouters, K. A., Daenen, K. L., Partouns Hendriks, I. E., Stessels, F., Louwagie, J., Smits, K. M., Weijenberg, M. P., Sanduleanu, S., Khalid - de Bakker, C. A., Oort, F. A., Meijer, G. A., Jonkers, D. M., Herman, J. G., de Bruine, A. P. & van Engeland, M., 1 Jan 2009, In : Journal of the National Cancer Institute. 101, 13, p. 916-27

Research output: Contribution to journalArticleAcademicpeer-review

105 Citations (Scopus)