20062020

Research output per year

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Research Output

2020

Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds

Schepers, M., Martens, N., Tiane, A., Vanbrabant, K., Liu, H-B., Luetjohann, D., Mulder, M. & Vanmierlo, T., May 2020, In : Neural Regeneration Research. 15, 5, p. 790-795 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2019

ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury

Sommer, D., Corstjens, I., Sanchez, S., Dooley, D., Lemmens, S., Van Broeckhoven, J., Bogie, J., Vanmierlo, T., Vidal, P. M., Rose-John, S., Gou-Fabregas, M. & Hendrix, S., Aug 2019, In : Brain Behavior and Immunity. 80, p. 129-145 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model

Bogie, J., Hoeks, C., Schepers, M., Tiane, A., Cuypers, A., Leijten, F., Chintapakorn, Y., Suttiyut, T., Pornpakakul, S., Struik, D., Kerksiek, A., Liu, H-B., Hellings, N., Martinez-Martinez, P., Jonker, J. W., Dewachter, I., Sijbrands, E., Walter, J., Hendriks, J., Groen, A. & 4 others, Staels, B., Luetjohann, D., Vanmierlo, T. & Mulder, M., 20 Mar 2019, In : Scientific Reports. 9, 16 p., 4908.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

From OPC to Oligodendrocyte: An Epigenetic Journey

Tiane, A., Schepers, M., Rombaut, B., Hupperts, R., Prickaerts, J., Hellings, N., van den Hove, D. & Vanmierlo, T., Oct 2019, In : Cells. 8, 10, 19 p., 1236.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Liver X Receptor Alpha Is Important in Maintaining Blood-Brain Barrier Function

Wouters, E., de Wit, N. M., Vanmol, J., van der Pol, S. M. A., Hof, B. V. H., Sommer, D., Loix, M., Geerts, D., Gustafsson, J. A., Steffensen, K. R., Vanmierlo, T., Bogie, J. F. J., Hendriks, J. J. A. & de Vries, H. E., 31 Jul 2019, In : Frontiers in Immunology. 10, p. 1-12 12 p., 1811.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Methylglyoxal-Derived Advanced Glycation Endproducts Accumulate in Multiple Sclerosis Lesions

Wetzels, S., Vanmierlo, T., Scheijen, J. L. J. M., van Horssen, J., Amor, S., Somers, V., Schalkwijk, C. G., Hendriks, J. J. A. & Wouters, K., 24 Apr 2019, In : Frontiers in Immunology. 10, 9 p., 855.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Phosphodiesterase Type 4 Inhibition in CNS Diseases

Blokland, A., Heckman, P., Vanmierlo, T., Schreiber, R., Paes, D. & Prickaerts, J., Dec 2019, In : Trends in Pharmacological Sciences. 40, 12, p. 971-985 15 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?"

Plat, J., Baumgartner, S., Vanmierlo, T., Luetjohann, D., Calkins, K. L., Burrin, D. G., Guthrie, G., Thijs, C., Te Velde, A. A., Vreugdenhil, A. C. E., Sverdlov, R., Garssen, J., Wouters, K., Trautwein, E. A., Wolfs, T. G., van Gorp, C., Mulder, M. T., Riksen, N. P., Groen, A. K. & Mensink, R. P., Apr 2019, In : Progress in Lipid Research. 74, p. 87-102 16 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

Schepers, M., Tiane, A., Paes, D., Sanchez, S., Rombaut, B., Piccart, E., Rutten, B. P. F., Brone, B., Hellings, N., Prickaerts, J. & Vanmierlo, T., 24 Jul 2019, In : Frontiers in Immunology. 10, p. 1-17 17 p., 1727.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

The role of receptor MAS in microglia-driven retinal vascular development

Foulquier, S., Caolo, V., Swennen, G., Milanova, I., Reinhold, S., Recarti, C., Alenina, N., Bader, M., Steckelings, U. M., Vanmierlo, T., Post, M. J., Jones, E. A., van Oostenbrugge, R. J. & Unger, T., Nov 2019, In : Angiogenesis. 22, 4, p. 481-489 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gestational stress in mouse dams negatively affects gestation and postpartum hippocampal BDNF and P11 protein levels

Vanmierlo, T., De Vry, J., Nelissen, E., Sierksma, A., Roumans, N., Steinbusch, H. W. M., Wennogle, L. P., van den Hove, D. & Prickaerts, J., 1 Apr 2018, In : Molecular and Cellular Neuroscience. 88, p. 292-299 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Progress and perspectives in plant sterol and plant stanol research

Jones, P. J. H., Shamloo, M., MacKay, D. S., Rideout, T. C., Myrie, S. B., Plat, J., Roullet, J-B., Baer, D. J., Calkins, K. L., Davis, H. R., Duell, P. B., Ginsberg, H., Gylling, H., Jenkins, D., Luetjohann, D., Moghadasian, M., Moreau, R. A., Mymin, D., Ostlund, R. E., Ras, R. T. & 5 others, Reparaz, J. O., Trautwein, E. A., Turley, S., Vanmierlo, T. & Weingaetner, O., Oct 2018, In : Nutrition Reviews. 76, 10, p. 725-746 22 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion

Santiago, A., Soares, L. M., Schepers, M., Milani, H., Vanmierlo, T., Prickaerts, J. & de Oliveira, R. M., 1 Aug 2018, In : Neuropharmacology. 138, p. 360-370 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

2017

Corrigendum: Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes

Bogie, J. F. J., Mailleux, J., Wouters, E., Jorissen, W., Grajchen, E., Vanmol, J., Wouters, K., Hellings, N., van Horssen, J., Vanmierlo, T. & Hendriks, J. J. A., 22 Dec 2017, In : Scientific Reports. 7, 1 p., 46925.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

Early-postnatal iron deficiency impacts plasticity in the dorsal and ventral hippocampus in piglets

Nelissen, E., De Vry, J., Antonides, A., Paes, D., Schepers, M., van der Staay, F. J., Prickaerts, J. & Vanmierlo, T., Jun 2017, In : International Journal of Developmental Neuroscience. 59, p. 47-51 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis

Wetzels, S., Wouters, K., Schalkwijk, C. G., Vanmierlo, T. & Hendriks, J. J. A., 15 Feb 2017, In : International journal of molecular sciences. 18, 2, 15 p., 421.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes

Bogie, J. F. J., Mailleux, J., Wouters, E., Jorissen, W., Grajchen, E., Vanmol, J., Wouters, K., Hellings, N., Van Horsen, J., Vanmierlo, T. & Hendriks, J. J. A., 20 Mar 2017, In : Scientific Reports. 7, 9 p., 44794.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses

Vanmierlo, T., Creemers, P., Akkerman, S., van Duinen, M., Sambeth, A., De Vry, J., Uz, T., Blokland, A. & Prickaerts, J., 15 Apr 2016, In : Behavioural Brain Research. 303, p. 26-33 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)
2015
5 Citations (Scopus)
2014

Delivery of DNA into the central nervous system via electroporation

De Vry, J., Vanmierlo, T., Martínez-Martínez, P., Losen, M., Temel, Y., Steinbusch, H., De Baets, M. & Prickaerts, J., 2014, Methods in molecular biology. Vol. 1121. p. 157-63 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

2 Citations (Scopus)

Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D

Sierksma, A. S. R., van den Hove, D. L. A., Pfau, F., Philippens, M., Bruno, O., Fedele, E., Ricciarelli, R., Steinbusch, H. W. M., Vanmierlo, T. & Prickaerts, J., Feb 2014, In : Neuropharmacology. 77, p. 120-130

Research output: Contribution to journalArticleAcademicpeer-review

33 Citations (Scopus)

Long-term effects of prenatal allopurinol treatment on brain plasticity markers in low and normal birth weight piglets

Prickaerts, J., Gieling, E. T., Bruder, A. K., van der Staay, F. J. & Vanmierlo, T., Apr 2014, In : International Journal of Developmental Neuroscience. 33, p. 29-32

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
2013

7,8-Dihydroxyflavone improves memory consolidation processes in rats and mice

Bollen, E., Vanmierlo, T., Akkerman, S., Wouters, C., Steinbusch, H. M. W. & Prickaerts, J., 15 Nov 2013, In : Behavioural Brain Research. 257, p. 8-12

Research output: Contribution to journalArticleAcademicpeer-review

2011

Apolipoprotein Isoform E4 Does Not Increase Coronary Heart Disease Risk in Carriers of Low-Density Lipoprotein Receptor Mutations

Versmissen, J., Oosterveer, D. M., Hoekstra, M., Out, R., Berbee, J. F. P., Blommesteijn-Touw, A. C., van Vark-van der Zee, L., Vongpromek, R., Vanmierlo, T., Defesche, J. C., Mulder, M., Kastelein, J. J. P. & Sijbrands, E. J. G., Dec 2011, In : Circulation : Cardiovascular Genetics. 4, 6, p. 655-U366

Research output: Contribution to journalArticleAcademicpeer-review

Differential effects on inhibition of cholesterol absorption by plant stanol and plant sterol esters in apoE-/- mice

Weingaertner, O., Ulrich, C., Luetjohann, D., Ismail, K., Schirmer, S. H., Vanmierlo, T., Boehm, M. & Laufs, U., Jun 2011, In : Cardiovascular Research. 90, 3, p. 484-492

Research output: Contribution to journalArticleAcademicpeer-review

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

Bruno, O., Fedele, E., Prickaerts, J., Parker, L. A., Canepa, E., Brullo, C., Cavallero, A., Gardella, E., Balbi, A., Domenicotti, C., Bollen, E., Gijselaers, H. J. M., Vanmierlo, T., Erb, K., Limebeer, C. L., Argellati, F., Marinari, U. M., Pronzato, M. A. & Ricciarelli, R., Dec 2011, In : British Journal of Pharmacology. 164, 8, p. 2054-2063

Research output: Contribution to journalArticleAcademicpeer-review

Markers of enhanced cholesterol absorption are a strong predictor for cardiovascular diseases in patients without diabetes mellitus

Weingaertner, O., Luetjohann, D., Vanmierlo, T., Mueller, S., Guenther, L., Herrmann, W., Boehm, M., Laufs, U. & Herrmann, M., Sep 2011, In : Chemistry and Physics of Lipids. 164, 6, p. 451-456

Research output: Contribution to journalArticleAcademicpeer-review

The plant sterol brassicasterol as additional CSF biomarker in Alzheimer's disease

Vanmierlo, T., Popp, J., Koelsch, H., Friedrichs, S., Jessen, F., Stoffel-Wagner, B., Bertsch, T., Hartmann, T., Maier, G. W., von Bergmann, K., Steinbusch, H., Mulder, M. & Luetjohann, D., Sep 2011, In : Acta Psychiatrica Scandinavica. 124, 3, p. 184-192

Research output: Contribution to journalArticleAcademicpeer-review

Validation of an isotope dilution gas chromatography-mass spectrometry method for analysis of 7-oxygenated campesterol and sitosterol in human serum

Husche, C., Weingaertner, O., Pettersson, H., Vanmierlo, T., Boehm, M., Laufs, U. & Luetjohann, D., Sep 2011, In : Chemistry and Physics of Lipids. 164, 6, p. 425-431

Research output: Contribution to journalArticleAcademicpeer-review

2010

Alterations in Brain Cholesterol Metabolism in the APPSLxPS1mut mouse, a Model for Alzheimer's Disease

Vanmierlo, T., Bloks, V. W., van Vark-van der Zee, L. C., Rutten, K., Kerksiek, A., Friedrichs, S., Sijbrands, E. J. G., Steinbusch, H. W., Kuipers, F., Luetjohann, D. & Mulder, M., 2010, In : Journal of Alzheimer's Disease. 19, 1, p. 117-127

Research output: Contribution to journalArticleAcademicpeer-review

Brain sterol metabolism : modulating Alzheimer’s disease

Vanmierlo, T., 1 Jan 2010, Maastricht: Maastricht University. 200 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
228 Downloads (Pure)
2006

Dietary plant sterols accumulate in the brain

Jansen, P. J., Lutjohann, D., Abildayeva, K., Vanmierlo, T., Plosch, T., Plat, J., von Bergmann, K., Groen, A. K., Ramaekers, F. C. S., Kuipers, F. & Mulder, M., 1 Jan 2006, In : Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids. 1761, p. 445-53

Research output: Contribution to journalArticleAcademicpeer-review

52 Citations (Scopus)