Simone Wielders

Research output

Research output per year 1990 1990 1991 1992 1993 1997 2003 2004 2013 2014 2015 2016 2017 2022 2022

• 14 Article
• 1 Conference article in proceeding

Research output per year

Research output per year

Search results

• Article

  Characterization of an apparently synonymous F5 mutation causing aberrant splicing and factor V deficiency

  Nuzzo, F., Bulato, C., Nielsen, B. I., Lee, K., Wielders, S. J., Simioni, P., Key, N. S. & Castoldi, E., Mar 2015, In: Haemophilia. 21, 2, p. 241-248

  Research output: Contribution to journal › Article › Academic › peer-review

• Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation

  Dargaud, Y., Scoazec, J. Y., Wielders, S. J. H., Trzeciak, C., Hackeng, T. M., Negrier, C., Hemker, H. C., Lindhout, T. & Castoldi, E., 26 Feb 2015, In: Blood. 125, 9, p. 1497-1501

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Characterization of Atherosclerotic Plaque Coating for Thrombosis Microfluidics Assays

  Karel, M. F. A., Lemmens, T. P., Tullemans, B. M. E., Wielders, S. J. H., Gubbins, E., van Beurden, D., van Rijt, S. & Cosemans, J. M. E. M., Feb 2022, In: Cellular and Molecular Bioengineering. 15, 1, p. 55-65 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Continuous registration of thrombin generation in plasma: Its use for the determination of the thrombin potential

  Hemker, H. C., Wielders, S., Kessels, H. & Beguin, S., 1993, In: Thrombosis and Haemostasis. 70, 4, p. 617-624 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  217 Downloads (Pure)

• Covalently-bound heparin makes collagen thromboresistant.

  Keuren, J. F. W., Wielders, S. J. H., Driessen, A., Verhoeven, M., Hendriks, M. & Lindhout, T., 1 Jan 2004, In: Arteriosclerosis Thrombosis and Vascular Biology. 24, 3, p. 613-617

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Determination of the levels of unfractionated and low-molecular-weight heparins in plasma: Their effect on thrombin-mediated feedback reactions in vivo

  Hemker, H. C., Beguin, S., Bendetowicz, A. V. & Wielders, S., 1991, In: Haemostasis. 21, 4, p. 258-272 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  File
  146 Downloads (Pure)

• Factor Xa Activation of Factor V Is of Paramount Importance in Initiating the Coagulation System: Lessons From a Tick Salivary Protein

  Schuijt, T. J., Bakhtiari, K., Daffre, S., DePonte, K., Wielders, S. J. H., Marquart, J. A., Hovius, J. W., van der Poll, T., Fikrig, E., Bunce, M. W., Camire, R. M., Nicolaes, G. A. F., Meijers, J. C. M. & van 't Veer, C., 16 Jul 2013, In: Circulation. 128, 3, p. 254-266

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• Identification of novel small molecule inhibitors of activated protein C

  Sperandio, O., Wildhagen, K. C. A. A., Schrijver, R., Wielders, S., Villoutreix, B. O. & Nicolaes, G. A. F., Jun 2014, In: Thrombosis Research. 133, 6, p. 1105-1114

  Research output: Contribution to journal › Article › Academic › peer-review

• Rational design of small molecules targeting the C2 domain of coagulation factor VIII

  Nicolaes, G. A. F., Kulharia, M., Voorberg, J., Kaijen, P. H., Wroblewska, A., Wielders, S., Schrijver, R., Sperandio, O. & Villoutreix, B. O., 2 Jan 2014, In: Blood. 123, 1, p. 113-120

  Research output: Contribution to journal › Article › Academic › peer-review

• The C-terminus of tissue factor pathway inhibitor-alpha inhibits factor V activation by protecting the Arg(1545) cleavage site

  van Doorn, P., Rosing, J., Wielders, S. J., Hackeng, T. M. & Castoldi, E., Jan 2017, In: Journal of Thrombosis and Haemostasis. 15, 1, p. 140-149 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

• The Mode of Action of CY216 and CY222 in Plasma

  Beguin, S., Wielders, S., Lormeau, J. C. & Hemker, H. C., 1992, In: Thrombosis and Haemostasis. 67, 1, p. 33-41 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  99 Downloads (Pure)

• The routine determination of the endogenous thrombin potential, first results in different forms of hyper- and hypocoagulability

  Wielders, S., Mukherjee, M., Michiels, J., Rijkers, D. T. S., Cambus, J-P., Knebel, R. W. C., Kakkar, V., Hemker, H. C. & Beguin, S., 1 Jan 1997, In: Thrombosis and Haemostasis. 77, 4, p. 629-636 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  147 Downloads (Pure)

• Toll-like receptor 9 gene expression in the post-thrombotic syndrome, residual thrombosis and recurrent deep venous thrombosis: A case-control study

  Cheung, Y. W., Bouman, A. C., Castoldi, E., Wielders, S. J., Spronk, H. M. H., ten Cate, H., Hoek - ten Cate, A. & ten Wolde, M., Apr 2016, In: Thrombosis Research. 140, p. 106-109

  Research output: Contribution to journal › Article › Academic › peer-review

• von Willebrand factor stimulates thrombin-induced exposure of procoagulant phospholipids on the surface of fibrin-adherent platelets

  Briedé, J. J., Wielders, S. J. H., Heemskerk, J. W. M., Baruch, D., Hemker, H. C. & Lindhout, T., 1 Jan 2003, In: Thrombosis and Haemostasis. 1, 3, p. 559-565 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  336 Downloads (Pure)