Research Output per year
Research Output 2000 2019
2019
Consumption of Nitrate-Rich Beetroot Juice with or without Vitamin C Supplementation Increases the Excretion of Urinary Nitrate, Nitrite, and N-nitroso Compounds in Humans
Berends, J. E., van den Berg, L. M. M., Guggeis, M. A., Henckens, N. F. T., Hossein, I. J., de Joode, M. E. J. R., Zamani, H., van Pelt, K. A. A. J., Beelen, N. A., Kuhnle, G. G., de Kok, T. M. C. M. & Van Breda, S. G. J., 1 May 2019, In : International Journal of Molecular Sciences. 20, 9, 15 p., 2277.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers
van Breda, S. G., Mathijs, K., Sagi-Kiss, V., Kuhnle, G. G., Van der Veer, B., Jones, R. R., Sinha, R., Ward, M. H. & de Kok, T. M., 17 Oct 2019, In : Environmental Health. 18, 1, 12 p., 87.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Improved Preventive Effects of Combined Bioactive Compounds Present in Different Blueberry Varieties as Compared to Single Phytochemicals
van Breda, S. G. J., Briede, J. J. & de Kok, T. M. C. M., Jan 2019, In : Nutrients. 11, 1, 14 p., 61.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
2018
A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases
Briede, J. J., Deferme, L., Wolters, J. E. J., Claessen, S. M. H., van den Beucken, T., Wagner, R. J., van Breda, S. G. & Kleinjans, J. C. S., 1 Apr 2018, In : Toxicology in Vitro. 48, p. 318-328 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Data on novel DNA methylation changes induced by valproic acid in human hepatocytes
Wolters, JJ., van Breda, SJ., Claessen, S., de Kok, TCM. & Kleinjans, JS., Feb 2018, In : Data in brief. 16, p. 161-171 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Drinking Water Nitrate and Human Health: An Updated Review
Ward, M. H., Jones, R. R., Brender, J. D., de Kok, T. M., Weyer, P. J., Nolan, B. T., Villanueva, C. M. & van Breda, S. G., 23 Jul 2018, In : International Journal of Environmental Research and Public Health. 15, 7, 31 p., 1557.Research output: Contribution to journal › Review article › Academic › peer-review
Open Access
Health effects of red meat products containing phytochemicals and reduced levels of nitrite: the PHYTOME project
10 Oct 2018, In : Toxicology Letters. 295, p. S141-S142 2 p.Research output: Contribution to journal › Conference Abstract/Poster in journal › Academic
Integrated 'omics analysis reveals new drug-induced mitochondrial perturbations in human hepatocytes
Wolters, J. E. J., van Breda, S. G. J., Grossmann, J., Fortes, C., Caiment, F. & Kleinjans, J. C. S., 1 Jun 2018, In : Toxicology Letters. 289, p. 1-13 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction
van Breda, S. G. J., Claessen, S. M. H., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T. M. C. M. & Kleinjans, J. C. S., 15 Jan 2018, In : Toxicology. 393, p. 160-170 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens
Limonciel, A., van Breda, S. G., Jiang, X., Tredwell, G. D., Wilmes, A., Aschauer, L., Siskos, A. P., Sachinidis, A., Keun, H. C., Kopp-Schneider, A., de Kok, T. M., Kleinjans, J. C. S. & Jennings, P., 3 Dec 2018, In : Frontiers in Genetics. 9, 15 p., 558.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
Smart Combinations of Bioactive Compounds in Fruits and Vegetables May Guide New Strategies for Personalized Prevention of Chronic Diseases
van Breda, S. G. J. & de Kok, T. M. C. M., 1 Jan 2018, In : Molecular Nutrition & Food Research. 62, 1, 12 p., 1700597.Research output: Contribution to journal › Review article › Academic › peer-review
2017
Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valproic Acid in Human Hepatocytes
Wolters, J. E. J., van Breda, S. G. J., Caiment, F., Claessen, S. M., de Kok, T. M. C. M. & Kleinjans, J. C. S., Oct 2017, In : Chemical Research in Toxicology. 30, 10, p. 1847-1854 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access
2016
Aflatoxin B1 induces persistent epigenomic effects in primary human hepatocytes associated with hepatocellular carcinoma
Rieswijk, L., Claessen, S. M. H., Bekers, O., van Herwijnen, M., Theunissen, D. H. J., Jennen, D. G. J., de Kok, T., Kleinjans, J. C. S. & van Breda, S. G. J., 28 Mar 2016, In : Toxicology. 350, p. 31-39 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Consumer awareness and credibility factors of health claims on innovative meat products in a cross-sectional population study in the Netherlands
Strijbos, C., Schluck, M., Bui, T., de Jong, I., van Leeuwen, M., von Tottleben, M. & van Breda, S. G., Dec 2016, In : Food Quality and Preference. 54, p. 13-22Research output: Contribution to journal › Article › Academic › peer-review
Dynamic Interplay between the Transcriptome and Methylome in Response to Oxidative and Alkylating Stress
Deferme, L., Wolters, J. E. J., Claessen, S. M. H., Theunissen, D., van den Beucken, T., Wagner, J. R., van Breda, S. G., Kleinjans, J. C. S. & Briede, J. J., Sep 2016, In : Chemical Research in Toxicology. 29, 9, p. 1428-1438Research output: Contribution to journal › Article › Academic › peer-review
Exploiting microRNA and mRNA profiles generated in vitro from carcinogen-exposed primary mouse hepatocytes for predicting in vivo genotoxicity and carcinogenicity
Rieswijk, L., Brauers, K. J. J., Coonen, M. L. J., Jennen, D. G. J., van Breda, S. G. J. & Kleinjans, J. C. S., Sep 2016, In : Mutagenesis. 31, 5, p. 603-615Research output: Contribution to journal › Article › Academic › peer-review
Integrative "-Omics" Analysis in Primary Human Hepatocytes Unravels Persistent Mechanisms of Cyclosporine A-Induced Cholestasis
Wolters, J. E. J., van Herwijnen, M. H. M., Theunissen, D. H. J., Jennen, D. G. J., Van den Hof, W. F. P. M., de Kok, T., Schaap, F. G., van Breda, S. G. J. & Kleinjans, J. C. S., Dec 2016, In : Chemical Research in Toxicology. 29, 12, p. 2164-2174Research output: Contribution to journal › Article › Academic › peer-review
"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015
Fernando, R. N., Chaudhari, U., Escher, S. E., Hengstler, J. G., Hescheler, J., Jennings, P., Keun, H. C., Kleinjans, J. C. S., Kolde, R., Kollipara, L., Kopp-Schneider, A., Limonciel, A., Nemade, H., Nguemo, F., Peterson, H., Prieto, P., Rodrigues, R. M., Sachinidis, A., Schaefer, C., Sickmann, A. & 8 others, , Jun 2016, In : Archives of Toxicology. 90, 6, p. 1529-1539Research output: Contribution to journal › Article › Academic › peer-review
2015
Development of novel tools for the in vitro investigation of drug-induced liver injury
Jiang, J., Wolters, J. EJ., van Breda, S. G., Kleinjans, J. C. & de Kok, T. M., 3 Oct 2015, In : Expert Opinion on Drug Metabolism & Toxicology. 11, 10, p. 1523-1537 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Epigenetic mechanisms underlying arsenic-associated lung carcinogenesis
van Breda, S. G. J., Claessen, S. M. H., Lo, K., van Herwijnen, M., Brauers, K. J. J., Lisanti, S., Theunissen, D. H. J., Jennen, D. G. J., Gaj, S., de Kok, T. & Kleinjans, J. C. S., Nov 2015, In : Archives of Toxicology. 89, 11, p. 1959-1969Research output: Contribution to journal › Article › Academic › peer-review
Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes
Rieswijk, L., Brauers, K. J. J., Coonen, M. L. J., Van Breda, S. G. J., Jennen, D. G. J. & Kleinjans, J. C. S., 2015, In : Mutagenesis. 30, 6, p. 771-784 14 p.Research output: Contribution to journal › Article › Academic › peer-review
The exposome concept in a human nutrigenomics study: Evaluating the impact of exposure to a complex mixture of phytochemicals using transcriptomics signatures
Van Breda, S. G. J., Wilms, L. C., Gaj, S., Jennen, D. G. J., Bried??, J. J., Kleinjans, J. C. S. & De Kok, T. M. C. M., 2015, In : Mutagenesis. 30, 6, p. 723-731 9 p.Research output: Contribution to journal › Article › Academic › peer-review
2014
Selenoprotein Gene Variants, Toenail Selenium Levels, and Risk for Advanced Prostate Cancer
Geybels, M. S., van den Brandt, P. A., Schouten, L. J., van Schooten, F. J., van Breda, S. G., Rayman, M. P., Green, F. R. & Verhage, B. A. J., 1 Jan 2014, In : Journal of the National Cancer Institute. 106, 3, dju003.Research output: Contribution to journal › Article › Academic › peer-review
2012
Genomics-Based Identification of Molecular Mechanisms behind the Cancer Preventive Action of Phytochemicals: Potential and Challenges
de Kok, T. M. C. M., van Breda, S. G. J. & Briede, J. J., Jan 2012, In : Current Pharmaceutical Biotechnology. 13, 1, p. 255-264Research output: Contribution to journal › Article › Academic › peer-review
2011
A Lyophilized Red Grape Pomace Containing Proanthocyanidin-Rich Dietary Fiber Induces Genetic and Metabolic Alterations in Colon Mucosa of Female C57BL/6J Mice
Lizarraga, D., Vinardell, M. P., Noe, V., van Delft, J. H., Alcarraz-Vizan, G., van Breda, S. G., Staal, Y., Guenther, U. L., Reed, M. A., Ciudad, C. J., Torres, J. L. & Cascante, M., Sep 2011, In : Journal of Nutrition. 141, 9, p. 1597-1604Research output: Contribution to journal › Article › Academic › peer-review
2010
Dietary acrylamide intake and risk of breast cancer in the UK women's cohort
Burley, V. J., Greenwood, D. C., Hepworth, S. J., Fraser, L. K., de Kok, T. M., van Breda, S. G. J., Kyrtopoulos, S. A., Botsivali, M., Kleinjans, J., McKinney, P. A. & Cade, J. E., 23 Nov 2010, In : British Journal of Cancer. 103, 11, p. 1749-1754 6 p.Research output: Contribution to journal › Article › Academic › peer-review
2009
Antioxidative and antigenotoxic properties of vegetables and dietary phytochemicals: The value of genomics biomarkers in molecular epidemiology.
de Kok, T. M., de Waard, P., Wilms, L. C. & van Breda, S. G., 1 Jan 2009, In : Molecular Nutrition & Food Research. 54, 2, p. 208-217Research output: Contribution to journal › Article › Academic › peer-review
Methylation status of CpG islands in the promoter region of genes differentially expressed in colonic mucosa from adenoma patients and controls in response to altered vegetable intake
van Breda, S. G., van Delft, J. H., Engels, L. G., Kleinjans, J. C. & Mathers, J. C., 1 Jan 2009, In : British Journal of Nutrition. 101, 9, p. 1295-9Research output: Contribution to journal › Article › Academic › peer-review
2008
Mechanisms of colorectal and lung cancer prevention by vegetables: a genomic approach.
van Breda, S. G., de Kok, T. & van Delft, J. H., 1 Jan 2008, In : Journal of Nutritional Biochemistry. 19, 3, p. 139-157Research output: Contribution to journal › Article › Academic › peer-review
Mechanisms of combined action of different chemopreventive dietary compounds: a review
de Kok, T. M., van Breda, S. G. & Manson, M. M., 1 Jan 2008, In : European Journal of Nutrition. 47, Suppl 2, p. 51-9Research output: Contribution to journal › Article › Academic › peer-review
Proton pump inhibitor therapy in gastro-oesophageal reflux disease decreases the oesophageal immune response but does not reduce the formation of DNA adducts
De Jonge, P. J., Siersema, P. D., van Breda, S. G., Van Zoest, K. P., Bac, D. J., Leeuwenburgh, I., Ouwendijk, R. J., van Dekken, H., Kusters, J. G. & Kuipers, E. J., 1 Jan 2008, In : Alimentary Pharmacology & Therapeutics. 28, 1, p. 127-36Research output: Contribution to journal › Article › Academic › peer-review
2007
Toenails: an easily accessible and long-term stable source of DNA for genetic analyses in large-scale epidemiological studies.
van Breda, S. G., Hogervorst, J. G., Schouten, L. J., Knaapen, A. M., van Delft, J. H. M., Goldbohm, R. A., van Schooten, F. J. & van den Brandt, P. A., 1 Jan 2007, In : Clinical Chemistry. 53, 6, p. 1168-1170Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review
2006
Potential protein markers for nutritional health effects on colorectal cancer in the mouse as revealed by proteomics analysis
Breikers, G., van Breda, S. G., Bouwman, F. G., van Herwijnen, M. H. M., Renes, J., Mariman, E. C., Kleinjans, J. C. & van Delft, J. H., 1 Jan 2006, In : Proteomics. 6, 9, p. 2844-2852Research output: Contribution to journal › Article › Academic › peer-review
2005
Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling
van Delft, J. H., van Agen, E., van Breda, S. G. J., van Herwijnen, M. H. M., Staal, Y. & Kleinjans, J. C., 1 Jan 2005, In : Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis. 575, 1-2, p. 17-33Research output: Contribution to journal › Article › Academic › peer-review
Vegetables affect the expression of genes involved in anticarcinogenic processes in the colonic mucosa of C57BL/6 female mice
van Breda, S. G. J., van Agen, E., van Sanden, S., Burzykowski, T., Kienhuis, A. S., Kleinjans, J. C. & van Delft, J. H., 1 Jan 2005, In : Journal of Nutrition. 135, 8, p. 1879-1888Research output: Contribution to journal › Article › Academic › peer-review
Vegetables affect the expression of genes involved in carcinogenic and anticarcinogenic processes in the lungs of female C57BL/6 mice
van Breda, S. G. J., van Agen, E., van Sanden, S., Burzykowski, T., Kleinjans, J. C. & van Delft, J. H., 1 Jan 2005, In : Journal of Nutrition. 135, 11, p. 2546-2552Research output: Contribution to journal › Article › Academic › peer-review
2004
Altered vegetable intake affects pivotal carcinogenesis pathways in colon mucosa from adenoma patients and controls
van Breda, S. G. J., van Agen, E., Engels, L. G. B., Moonen, E. J. C., Kleinjans, J. C. & van Delft, J. H., 1 Jan 2004, In : Carcinogenesis. 25, 11, p. 2207-2216Research output: Contribution to journal › Article › Academic › peer-review
Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling
van Delft, J. H., van Agen, E., van Breda, S. G. J., van Herwijnen, M. H. M., Staal, Y. & Kleinjans, J. C., 1 Jan 2004, In : Carcinogenesis. 25, 7, p. 1265-1276Research output: Contribution to journal › Article › Academic › peer-review
445
Downloads
(Pure)
Vegetable induced gene expression changes in anticarcinogenic pathways in human and mouse tissues
van Breda, S. G. J., 1 Jan 2004, Maastricht: Maastricht University. 197 p.Research output: Thesis › Doctoral Thesis › Internal
Open Access
File
2000
16
Citations
(Scopus)
Applicability of induced sputum for molecular dosimetry of exposure to inhalatory carcinogens: P-32-postlabeling of lipophilic DNA adducts in smokers and nonsmokers
Nia, A. B., Maas, L. M., van Breda, S. G. J., Curfs, D. M. J., Kleinjans, J. C. S., Wouters, E. F. M. & van Schooten, F. J., 1 Jan 2000, In : Cancer Epidemiology Biomarkers & Prevention. 9, p. 367-372 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?
van Maanen, J. M. S., Albering, H. J., de Kok, T. M. C. M., van Breda, S. G. J., Curfs, D. M. J., Vermeer, I. T. M., Ambergen, A. W., Wolffenbuttel, B. H. R., Kleinjans, J. C. S. & Reeser, H. M., 1 Jan 2000, In : Environmental Health Perspectives. 108, 5, p. 457-461 5 p.Research output: Contribution to journal › Article › Academic › peer-review