20142019

Research output per year

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Research Output

  • 34 Article
  • 3 Review article
  • 1 Conference Abstract/Poster in journal

A critical evaluation of the current state-of-the-art in quantitative imaging mass spectrometry

Ellis, S. R., Bruinen, A. L. & Heeren, R. M. A., Feb 2014, In : Analytical and Bioanalytical Chemistry. 406, 5, p. 1275-1289

Research output: Contribution to journalArticleAcademicpeer-review

42 Citations (Scopus)

Advances in mass spectrometry imaging enabling observation of localised lipid biochemistry within tissues

Bowman, A. P., Heeren, R. M. A. & Ellis, S. R., Nov 2019, In : Trac-Trends in Analytical Chemistry. 120, 10 p., 115197.

Research output: Contribution to journalReview articleAcademicpeer-review

Automated, parallel mass spectrometry imaging and structural identification of lipids

Ellis, S. R., Paine, M. R. L., Eijkel, G. B., Pauling, J. K., Husen, P., Jervelund, M. W., Hermansson, M., Ejsing, C. S. & Heeren, R. M. A., Jul 2018, In : Nature Methods. 15, 7, p. 515–518 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Class-specific depletion of lipid ion signals in tissues upon formalin fixation

Vos, D. R. N., Bowman, A. P., Heeren, R. M. A., Balluff, B. & Ellis, S. R., Dec 2019, In : International Journal of Mass Spectrometry. 446, p. 1-9 9 p., 116212.

Research output: Contribution to journalArticleAcademicpeer-review

Combined X-ray CT and mass spectrometry for biomedical imaging applications

Schioppa, E. . J., Ellis, S., Bruinen, A. L., Visser, J., Heeren, R. M. A., Uher, J. & Koffeman, E., Apr 2014, In : Journal of Instrumentation. 9

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Design and Performance of a Novel Interface for Combined Matrix-Assisted Laser Desorption Ionization at Elevated Pressure and Electrospray Ionization with Orbitrap Mass Spectrometry

Belov, M. E., Ellis, S. R., Dilillo, M., Paine, M. R. L., Danielson, W. F., Anderson, G. A., de Graaf, E. L., Eijkel, G. B., Heeren, R. M. A. & McDonnell, L. A., 18 Jul 2017, In : Analytical Chemistry. 89, 14, p. 7493-7501 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Digestion-Free Analysis of Peptides from 30-year-old Formalin-Fixed, Paraffin-Embedded Tissue by Mass Spectrometry Imaging

Paine, M. R. L., Ellis, S. R., Maloney, D., Heeren, R. M. A. & Verhaert, P. D. E. M., 7 Aug 2018, In : Analytical Chemistry. 90, 15, p. 9272-9280 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Direct Ion Imaging Approach for Investigation of Ion Dynamics in Multipole Ion Guides

Syed, S. U. A. H., Maher, S., Eijkel, G. B., Ellis, S. R., Jjunju, F., Taylor, S. & Heeren, R. M. A., 7 Apr 2015, In : Analytical Chemistry. 87, 7, p. 3714-3720

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation

Skraskova, K., Claude, E., Jones, E. A., Towers, M., Ellis, S. R. & Heeren, R. M. A., 15 Jul 2016, In : Methods. 104, p. 69-78

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research

Barre, F. P. Y., Paine, M. R. L., Flinders, B., Trevitt, A. J., Kelly, P. D., Ait-Belkacem, R., Garcia, J. P., Creemers, L. B., Stauber, J., Vreeken, R. J., Cillero-Pastor, B., Ellis, S. R. & Heeren, R. M. A., 20 Aug 2019, In : Analytical Chemistry. 91, 16, p. 10840-10848 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Experimental Investigation of the 2D Ion Beam Profile Generated by an ESI Octopole-QMS System

Syed, S. U. A. H., Eijkel, G. B., Kistemaker, P., Ellis, S., Maher, S., Smith, D. F. & Heeren, R. M. A., Oct 2014, In : Journal of the American Society for Mass Spectrometry. 25, 10, p. 1780-1787

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Host-based lipid inflammation drives pathogenesis in Francisella infection

Scott, A. J., Post, J. M., Lerner, R., Ellis, S. R., Lieberman, J., Shirey, K. A., Heeren, R. M. A., Bindila, L. & Ernst, R. K., 21 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 47, p. 12596-12601 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Increased throughput and ultra-high mass resolution in DESI FT-ICR MS imaging through new-generation external data acquisition system and advanced data processing approaches

Kooijman, P. C., Nagornov, K. O., Kozhinov, A. N., Kilgour, D. P. A., Tsybin, Y. O., Heeren, R. M. A. & Ellis, S. R., 9 Jan 2019, In : Scientific Reports. 9, p. 1-11 11 p., 8.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Laser post-ionisation combined with a high resolving power orbitrap mass spectrometer for enhanced MALDI-MS imaging of lipids

Ellis, S. R., Soltwisch, J., Paine, M. R. L., Dreisewerd, K. & Heeren, R. M. A., 7 Jul 2017, In : Chemical Communications. 53, 53, p. 7246-7249 4 p.

Research output: Contribution to journalArticleAcademicpeer-review

Maintenance of Deep Lung Architecture and Automated Airway Segmentation for 3D Mass Spectrometry Imaging

Scott, A. J., Chandler, C. E., Ellis, S. R., Heeren, R. M. A. & Ernst, R. K., 27 Dec 2019, In : Scientific Reports. 9, p. 1-12 12 p., 20160.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

MALDI Mass Spectrometry Imaging in Microscope Mode with Infrared Lasers: Bypassing the Diffraction Limits

Soltwisch, J., Goeritz, G., Jungmann, J. H., Kiss, A., Smith, D. F., Ellis, S. R. & Heeren, R. M. A., 7 Jan 2014, In : Analytical Chemistry. 86, 1, p. 321-325

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)

Mass Spectrometry Imaging with Isomeric Resolution Enabled by Ozone-Induced Dissociation

Paine, M. R. L., Poad, B. L. J., Eijkel, G. B., Marshall, D. L., Blanksby, S. J., Heeren, R. M. A. & Ellis, S. R., 13 Aug 2018, In : Angewandte Chemie-International Edition. 57, 33, p. 10530-10534 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Methods for full resolution data exploration and visualization for large 2D and 3D mass spectrometry imaging datasets

Klinkert, I., Chughtai, K., Ellis, S. R. & Heeren, R. M. A., 1 Apr 2014, In : International Journal of Mass Spectrometry. 362, p. 40-47

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

More from less: high-throughput dual polarity lipid imaging of biological tissues

Ellis, S. R., Cappell, J., Potocnik, N. O., Balluff, B., Hamaide, J., Van der Linden, A. & Heeren, R. M. A., 2016, In : Analyst. 141, 12, p. 3832-3841

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

NF-kappa B-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis

Remels, A. H. V., Derks, W. J. A., Cillero-Pastor, B., Verhees, K. J. P., Kelders, M. C., Heggermont, W., Carai, P., Summer, G., Ellis, S. R., de Theije, C. C., Heeren, R. M. A., Heymans, S., Papageorgiou, A. P. & van Bilsen, M., Aug 2018, In : Biochimica et Biophysica Acta-Molecular Basis of Disease. 1864, 8, p. 2579-2589 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Radical Generation from the Gas-Phase Activation of Ionized Lipid Ozonides

Ellis, S. R., Pham, H. T., Panhuis, M. I. H., Trevitt, A. J., Mitchell, T. W. & Blanksby, S. J., Jul 2017, In : Journal of the American Society for Mass Spectrometry. 28, 7, p. 1345-1358 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Rapid Identification of Ischemic Injury in Renal Tissue by Mass-Spectrometry Imaging

van Smaalen, T. C., Ellis, S. R., Mascini, N. E., Siegel, T. P., Cillero-Pastor, B., Hillen, L. M., van Heurn, L. W. E., Peutz-Kootstra, C. J. & Heeren, R. M. A., 5 Mar 2019, In : Analytical Chemistry. 91, 5, p. 3575-3581 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Reshaping Lipid Biochemistry by Pushing Barriers in Structural Lipidomics

Siegel, T. P., Ekroos, K. & Ellis, S. R., 13 May 2019, In : Angewandte Chemie-International Edition. 58, 20, p. 6492-6501 10 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Simultaneous lipidomic and transcriptomic profiling in mouse brain punches of acute epileptic seizure model compared to controls

Lerner, R., Post, J. M., Ellis, S. R., Vos, D. R. N., Heeren, R. M. A., Lutz, B. & Bindila, L., Feb 2018, In : Journal of Lipid Research. 59, 2, p. 283-297 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

Spatial Autocorrelation in Mass Spectrometry Imaging

Cassese, A., Ellis, S. R., Ogrinc Potocnik, N., Burgermeister, E., Ebert, M., Walch, A., Van Den Maagdenberg, A. M. J. M., McDonnell, L. A., Heeren, R. M. A. & Balluff, B., 7 Jun 2016, In : Analytical Chemistry. 88, 11, p. 5871-5878 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Spatial Systems Lipidomics Reveals Nonalcoholic Fatty Liver Disease Heterogeneity

Scupakova, K., Soons, Z., Ertaylan, G., Pierzchalski, K. A., Eijkel, G. B., Ellis, S. R., Greve, J. W., Driessen, A., Verheij, J., De Kok, T. M., Damink, S. W. M. O., Rensen, S. S. & Heeren, R. M. A., 17 Apr 2018, In : Analytical Chemistry. 90, 8, p. 5130-5138 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Spectroscopic data handling at petabyte scale

Davies, A. N., Ellis, S., Balluff, B. & Heeren, R., 2016, In : Spectroscopy Europe. 28, 1, p. 15-17

Research output: Contribution to journalArticleProfessional

Stigmatic imaging of secondary ions in MeV-SIMS spectrometry by linear Time-of-Flight mass spectrometer and the TimePix detector

Jencic, B., Sepec, L., Vavpetic, P., Kelemen, M., Rupnik, Z., Vencelj, M., Vogel-Mikus, K., Potocnik, N. O., Ellis, S. R., Heeren, R. & Pelicon, P., 1 Aug 2019, In : Nuclear Instruments & Methods in Physics Research Section B-Beam Interactions with Materials and Atoms. 452, p. 1-6 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Strategies for managing multi-patient 3D mass spectrometry imaging data

Vos, D. R. N., Jansen, R. L., Lucas, M., Paine, M. R. L., de Boer, O. J., Meijer, S. L., Savci-Heijink, C. D., Marquering, H. A., de Bruin, D. M., Heeren, R. M. A., Ellis, S. R. & Balluff, B., 20 Feb 2019, In : Journal of Proteomics. 193, p. 184-191 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Targeted Drug and Metabolite Imaging: Desorption Electrospray Ionization Combined with Triple Quadrupole Mass Spectrometry

Lamont, L., Eijkel, G. B., Jones, E. A., Flinders, B., Ellis, S. R., Porta Siegel, T., Heeren, R. M. A. & Vreeken, R. J., 20 Nov 2018, In : Analytical Chemistry. 90, 22, p. 13229-13235 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Three-Dimensional Mass Spectrometry Imaging Identifies Lipid Markers of Medulloblastoma Metastasis

Paine, M. R. L., Liu, J., Huang, D., Ellis, S. R., Trede, D., Kobarg, J. H., Heeren, R. M. A., Fernandez, F. M. & MacDonald, T. J., 18 Feb 2019, In : Scientific Reports. 9, p. 1-10 10 p., 2205.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Understanding Detrimental and Beneficial Grain Boundary Effects in Halide Perovskites

Adhyaksa, G. W. P., Brittman, S., Abolins, H., Lof, A., Li, X., Keelor, J. D., Luo, Y., Duevski, T., Heeren, R. M. A., Ellis, S. R., Fenning, D. P. & Garnett, E. C., 27 Dec 2018, In : Advanced Materials. 30, 52, 9 p., 1804792.

Research output: Contribution to journalArticleAcademicpeer-review

20 Citations (Scopus)

Visualizing hepatocellular amino acid kinetics through mass spectrometry imaging of stable isotopes

Arts, M., Soons, Z., Dubois, L. J., Pierzchalski, K. A., Ellis, S. R., Balluff, B., Eijkel, G. B., Cramer, T., Lieuwes, N., Agten, S. M., Hackeng, T. M., Van Loon, L. J., Heeren, R. M. & Damink, S. W. O., 2017, In : Journal of Hepatology. 66, 1, p. S43-S44 2 p.

Research output: Contribution to journalConference Abstract/Poster in journalAcademic

Visualizing molecular distributions for biomaterials applications with mass spectrometry imaging: a review

Paine, M. R. L., Kooijman, P. C., Fisher, G. L., Heeren, R. M. A., Fernandez, F. M. & Ellis, S. R., 28 Sep 2017, In : Journal of Materials Chemistry. B, Materials for Biology and Medicine. 5, 36, p. 7444-7460 17 p.

Research output: Contribution to journalReview articleAcademicpeer-review