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Gestational Weight Gain by Maternal Pre-pregnancy BMI and Childhood Problem Behaviours in School-Age Years: A Pooled Analysis of Two European Birth Cohorts

Tore, E. C., Antoniou, E. E., de Groot, R. H. M., Gielen, M., Godschalk, R. W. L., Roumeliotaki, T., Smits, L., Southwood, T. R., Spaanderman, M. E. A., Stratakis, N., Vafeiadi, M., Chatzi, V. L. & Zeegers, M. P., Oct 2020, In : Maternal and Child Health Journal. 24, 10, p. 1288-1298 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2019

Gene expression and DNA methylation as mechanisms of disturbed metabolism in offspring after exposure to a prenatal HF diet

Rouschop, S. H., Karl, T., Risch, A., van Ewijk, P. A., Schrauwen-Hinderling, V. B., Opperhuizen, A., van Schooten, F. J. & Godschalk, R. W., Jul 2019, In : Journal of Lipid Research. 60, 7, p. 1250-1259 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Impact of Weight Loss Strategies on Obesity-Induced DNA Damage

Setayesh, T., Misik, M., Langie, S. A. S., Godschalk, R., Waldherr, M., Bauer, T., Leitner, S., Bichler, C., Prager, G., Krupitza, G., Haslberger, A. & Knasmueller, S., Sep 2019, In : Molecular Nutrition & Food Research. 63, 17, 9 p., 1900045.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Interaction between dietary acrylamide intake and genetic variants for estrogen receptor-positive breast cancer risk

Hogervorst, J. G. F., van den Brandt, P. A., Godschalk, R. W. L., van Schooten, F-J. & Schouten, L. J., Apr 2019, In : European Journal of Nutrition. 58, 3, p. 1033-1045 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Polyunsaturated fatty acid status at birth, childhood growth, and cardiometabolic risk: a pooled analysis of the MEFAB and RHEA cohorts

Stratakis, N., Gielen, M., Margetaki, K., de Groot, R. H. M., Apostolaki, M., Chalkiadaki, G., Vafeiadi, M., Leventakou, V., Karachaliou, M., Godschalk, R. W., Kogevinas, M., Stephanou, E. G., Zeegers, M. P. & Chatzi, L., Apr 2019, In : European Journal of Clinical Nutrition. 73, 4, p. 566-576 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

The association of maternal polyunsaturated fatty acids during pregnancy with social competence and problem behaviours at 7 years of age: The MEFAB cohort

Tore, E. C., Gielen, M., Antoniou, E. E., de Groot, R. H. M., Godschalk, R. W. L., Southwood, T. R., Smits, L., Stratakis, N., van de Wurff, I. S. M. & Zeegers, M. P., May 2019, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 144, p. 1-9 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Bulky DNA adduct levels in normal-appearing colon mucosa, and the prevalence of colorectal adenomas

Ho, V., Peacock, S., Massey, T. E., Godschalk, R. W., van Schooten, F. J., Ashbury, J. E., Vanner, S. J. & King, W. D., 17 Nov 2018, In : Biomarkers. 23, 8, p. 735-741 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing

Marchetti, F., Aardema, M. J., Beevers, C., van Benthem, J., Godschalk, R., Williams, A., Yauk, C. L., Young, R. & Douglas, G. R., Aug 2018, In : Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 832, p. 7-18 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Paternal Exposure to Environmental Chemical Stress Affects Male Offspring's Hepatic Mitochondria

Godschalk, R., Remels, A., Hoogendoorn, C., van Benthem, J., Luijten, M., Duale, N., Brunborg, G., Olsen, A-K., Bouwman, F. G., Munnia, A., Peluso, M., Mariman, E. & van Schooten, F. J., Mar 2018, In : Toxicological Sciences. 162, 1, p. 241-250 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

PUFA status at birth and allergy-related phenotypes in childhood: a pooled analysis of the Maastricht Essential Fatty Acid Birth (MEFAB) and RHEA birth cohorts

Stratakis, N., Gielen, M., Margetaki, K., de Groot, R. H. M., Apostolaki, M., Chalkiadaki, G., Vafeiadi, M., Leventakou, V., Godschalk, R. W., Kogevinas, M., Stephanou, E. G., Zeegers, M. P. & Chatzi, L., 28 Jan 2018, In : British Journal of Nutrition. 119, 2, p. 202-210 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488

Marchetti, F., Aardema, M., Beevers, C., van Benthem, J., Douglas, G. R., Godschalk, R., Yauk, C. L., Young, R. & Williams, A., Aug 2018, In : Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 832, p. 19-28 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2017

Acidic cellular microenvironment modifies carcinogen-induced DNA damage and repair

Shi, Q., Maas, L., Veith, C., Van Schooten, F. J. & Godschalk, R. W., Jun 2017, In : Archives of Toxicology. 91, 6, p. 2425-2441 17 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Altered gene expression profiles in the lungs of benzo [a]pyrene-exposed mice in the presence of lipopolysaccharide-induced pulmonary inflammation

Shi, Q., Fijten, R. R., Spina, D., Vasquez, R. Y., Arlt, V. M., Godschalk, R. W. & Van Schooten, F. J., 1 Dec 2017, In : Toxicology and Applied Pharmacology. 336, p. 8-19 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access

Effect of interleukin (IL)-8 on benzo[a]pyrene metabolism and DNA damage in human lung epithelial cells

Shi, Q., Boots, A. W., Maas, L., Veith, C., van Kuijk, K., Haenen, G. R., Godschalk, R. W. & Van Schooten, F. J., 15 Apr 2017, In : Toxicology. 381, p. 64-74 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Exposure to meat-derived carcinogens and bulky DNA adduct levels in normal-appearing colon mucosa

Ho, V., Brunetti, V., Peacock, S., Massey, T. E., Godschalk, R. W. L., van Schooten, F. J., Ashbury, J. E., Vanner, S. J. & King, W. D., Sep 2017, In : Mutation Research-Genetic Toxicology and Environmental Mutagenesis. 821, p. 5-12 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Interactions between dietary acrylamide intake and genes for ovarian cancer risk

Hogervorst, J. G. F., van den Brandt, P. A., Godschalk, R. W. L., van Schooten, F-J. & Schouten, L. J., May 2017, In : European Journal of Epidemiology. 32, 5, p. 431-441 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Polyunsaturated fatty acid levels at birth and child-to-adult growth: Results from the MEFAB cohort

Stratakis, N., Gielen, M., Margetaki, K., Godschalk, R. W., van der Wurff, I. S. M., Rouschop, S., Ibrahim, A., Antoniou, E., Chatzi, L., de Groot, R. H. M. & Zeegers, M. P., Nov 2017, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 126, p. 72-78 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice

Langie, S. A. S., Cameron, K. M., Ficz, G., Oxley, D., Tomaszewski, B., Gorniak, J. P., Maas, L. M., Godschalk, R. W. L., van Schooten, F. J., Reik, W., von Zglinicki, T. & Mathers, J. C., Feb 2017, In : Genes. 8, 2, 19 p., 75.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2016

Association between prenatal and current exposure to selected LCPUFAs and school performance at age 7

van der Wurff, I. S. M., Bakker, E. C., Hornstra, G., Kirschner, P. A., Gielen, M., Godschalk, R. W. L., Kremers, S., Zeegers, M. P. & de Groot, R. H. M., May 2016, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 108, p. 22-29

Research output: Contribution to journalArticleAcademicpeer-review

Does Ataxia Telangiectasia Mutated (ATM) protect testicular and germ cell DNA integrity by regulating the redox status?

Godschalk, R. W. L., Vanhees, K., Maas, L., Drittij - Reijnders, M. J., Pachen, D., van Doorn-Khosrovani, S. V. W., van Schooten, F. J. & Haenen, G. R. M. M., Aug 2016, In : Reproductive Toxicology. 63, p. 169-173

Research output: Contribution to journalArticleAcademicpeer-review

Potential role of gene-environment interactions in ion transport mechanisms in the etiology of renal cell cancer

Deckers, I. A. G., van den Brandt, P. A., van Engeland, M., van Schooten, F. J., Godschalk, R. W. L., Keszei, A. P., Hogervorst, J. G. F. & Schouten, L. J., 30 Sep 2016, In : Scientific Reports. 6, 34262.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

Krais, A. M., Speksnijder, E. N., Melis, J. P., Indra, R., Moserova, M., Godschalk, R. W., van Schooten, F-J., Seidel, A., Kopka, K., Schmeiser, H. H., Stiborova, M., Phillips, D. H., Luijten, M. & Arlt, V. M., Apr 2016, In : Archives of Toxicology. 90, 4, p. 839-851 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)
Open Access
1 Citation (Scopus)

Canonical autophagy does not contribute to cellular radioresistance

Schaaf, M. B., Jutten, B., Keulers, T. G., Savelkouls, K. G., Peeters, H. J., van den Beucken, T., van Schooten, F. J., Godschalk, R. W., Vooijs, M. & Rouschop, K. M., Mar 2015, In : Radiotherapy and Oncology. 114, 3, p. 406-412 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Effects of benzo a pyrene on mouse germ cells: heritable DNA mutation, testicular cell hypomethylation and their interaction with nucleotide excision repair

Godschalk, R. W. L., Verhofstad, N., Verheijen, M., Yauk, C. L., Linschooten, J. O., van de Steeg, H., van Oostrom, C. T., van Benthem, J. & van Schooten, F. J., 1 Jan 2015, In : Toxicology Research. 4, 3, p. 718-724 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Environmental, Dietary, Maternal, and Fetal Predictors of Bulky DNA Adducts in Cord Blood: A European Mother-Child Study (NewGeneris)

Pedersen, M., Mendez, M. A., Schoket, B., Godschalk, R. W., Espinosa, A., Landstrom, A., Villanueva, C. M., Merlo, D. F., Fthenou, E., Gracia-Lavedan, E., van Schooten, F. J., Hoek, G., Brunborg, G., Meltzer, H. M., Alexander, J., Nielsen, J. K., Sunyer, J., Wright, J., Kovacs, K., de Hoogh, K. & 19 others, Gutzkow, K. B., Hardie, L. J., Chatzi, L., Knudsen, L. E., Anna, L., Ketzel, M., Haugen, M., Botsivali, M., Nieuwenhuijsen, M. J., Cirach, M., Toledano, M. B., Smith, R. B., Fleming, S., Agramunt, S., Kyrtopoulos, S. A., Lukacs, V., Kleinjans, J. C., Segerback, D. & Kogevinas, M., Apr 2015, In : Environmental Health Perspectives. 123, 4, p. 374-380 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Environmental carcinogens and mutational pathways in atherosclerosis

Pulliero, A., Godschalk, R., Andreassi, M. G., Danielle, C., van Schooten, F. J. & Izzotti, A., 1 Jan 2015, In : International Journal of Hygiene and Environmental Health. 218, 3, p. 293-312

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Gene-diet interactions in exposure to heterocyclic aromatic amines and bulky DNA adduct levels in blood leukocytes

Ho, V., Peacock, S., Massey, T. E., Godschalk, R. W., van Schooten, F. J., Chen, J. & King, W. D., Aug 2015, In : Environmental and Molecular Mutagenesis. 56, 7, p. 609-620 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

In vitro effects of low-level aldehyde exposures on human umbilical vein endothelial cells

Cheah, N. P., Pennings, J. L. A., Vermeulen, J. P., Godschalk, R. W. L., van Schooten, F. J. & Opperhuizen, A., 1 Jan 2015, In : Toxicology Research. 4, 5, p. 1250-1259

Research output: Contribution to journalArticleAcademicpeer-review

Polymorphisms in genes of the renin-angiotensin-aldosterone system and renal cell cancer risk: Interplay with hypertension and intakes of sodium, potassium and fluid

Deckers, I. A., van den Brandt, P. A., van Engeland, M., van Schooten, F. J., Godschalk, R. W., Keszei, A. P. & Schouten, L. J., 1 Mar 2015, In : International Journal of Cancer. 136, 5, p. 1104-1116 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

13 Citations (Scopus)

Pulmonary Inflammation Impacts on CYP1A1-Mediated Respiratory Tract DNA Damage Induced by the Carcinogenic Air Pollutant Benzo[a]pyrene

Arlt, V. M., Krais, A. M., Godschalk, R. W., Riffo-Vasquez, Y., Mrizova, I., Roufosse, C. A., Corbin, C., Shi, Q., Frei, E., Stiborova, M., van Schooten, F. J., Phillips, D. H. & Spina, D., 1 Jan 2015, In : Toxicological Sciences. 146, 2, p. 213-225

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Scopus)

The oxidation of p-phenylenediamine, an ingredient used for permanent hair dyeing purposes, leads to the formation of hydroxyl radicals: Oxidative stress and DNA damage in human immortalized keratinocytes

Zanoni, T. B., Hudari, F., Munnia, A., Peluso, M., Godschalk, R. W., Zanoni, M. V., den Hartog, G. J., Bast, A., Barros, S. B., Maria-Engler, S. S., Hageman, G. J. & de Oliveira, D. P., 15 Dec 2015, In : Toxicology Letters. 239, 3, p. 194-204 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

The shifting perception on antioxidants: The case of vitamin E and beta-carotene

Vrolijk, M. F., Opperhuizen, A., Jansen, E. H., Godschalk, R. W., van Schooten, F. J., Bast, A. & Haenen, G. R., 1 Jan 2015, In : Redox Biology. 4C, p. 272-278

Research output: Contribution to journalArticleAcademic

15 Citations (Scopus)
2014

Association between polyunsaturated fatty acid concentrations in maternal plasma phospholipids during pregnancy and offspring adiposity at age 7: The MEFAB cohort.

de Vries, P. S., Gielen, M., Rizopoulos, D., Rump, P., Godschalk, R., Hornstra, G. & Zeegers, M. P., Sep 2014, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 91, 3, p. 81-85 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

19 Citations (Scopus)

DNA from Nails for Genetic Analyses in Large-Scale Epidemiologic Studies

Hogervorst, J. G. F., Godschalk, R. W. L., van den Brandt, P. A., Weijenberg, M. P., Verhage, B. A. J., Jonkers, L., Goessens, J., Simons, C. C. J. M., Vermeesch, J. R., van Schooten, F. J. & Schouten, L. J., Dec 2014, In : Cancer Epidemiology Biomarkers & Prevention. 23, 12, p. 2703-2712 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene

Schults, M. A. C., Sanen, K., Godschalk, R. W., Theys, J., van Schooten, F. J. & Chiu, R. K., Nov 2014, In : Mutagenesis. 29, 6, p. 481-487 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Micronuclei in Cord Blood Lymphocytes and Associations with Biomarkers of Exposure to Carcinogens and Hormonally Active Factors, Gene Polymorphisms, and Gene Expression: The NewGeneris Cohort

Merlo, D. F., Agramunt, S., Anna, L., Besselink, H., Botsivali, M., Brady, N. J., Ceppi, M., Chatzi, L., Chen, B., Decordier, I., Farmer, P. B., Fleming, S., Fontana, V., Foersti, A., Fthenou, E., Gallo, F., Georgiadis, P., Gmuender, H., Godschalk, R. W., Granum, B. & 25 others, Hardie, L. J., Hemminki, K., Hochstenbach, K., Knudsen, L. E., Kogevinas, M., Kovacs, K., Kyrtopoulos, S. A., Lovik, M., Nielsen, J. K., Nygaard, U. C., Pedersen, M., Rydberg, P., Schoket, B., Segerback, D., Singh, R., Sunyer, J., Tornqvist, M., van Loveren, H., van Schooten, F. J., vande Loock, K., von Stedingk, H., Wright, J., Kleinjans, J. C., Kirsch-Volders, M. & van Delft, J. H. M., Feb 2014, In : Environmental Health Perspectives. 122, 2, p. 193-200

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Redox and epigenetic regulation of the APE1 gene in the hippocampus of piglets: The effect of early life exposures

Langie, S. A., Kowalczyk, P., Tomaszewski, B., Vasilaki, A., Maas, L. M., Moonen, E., Palagani, A., Godschalk, R. W., Tudek, B., van Schooten, F. J., Berghe, W. V., Zabielski, R. & Mathers, J. C., Jun 2014, In : Dna Repair. 18, p. 52-62 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories.

Godschalk, R. W., Ersson, C., Stepnik, M., Ferlilska, M., Palus, J., Teixeira, J. P., Costa, S., Jones, G. D., Higgins, J. A., Kain, J., Moller, L., Forchhammer, L., Loft, S., Lorenzo, Y., Collins, A. R., van Schooten, F. J., Laffon, B., Valdiglesias, V., Cooke, M., Mistry, V. & 12 others, Karbaschi, M., Phillips, D. H., Sozeri, O., Routledge, M. N., Smith, K., Riso, P., Porrini, M., Lopez de Cerain, A., Azqueta, A., Matullo, G., Allione, A. & Moller, P., Jul 2014, In : Mutagenesis. 29, 4, p. 241-249 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

You are what you eat, and so are your children: the impact of micronutrients on the epigenetic programming of offspring.

Vanhees, K., Vonhogen, I. G., van Schooten, F. J. & Godschalk, R. W. L., 1 Jan 2014, In : Cellular and Molecular Life Sciences. 71, 2, p. 271-285 15 p.

Research output: Contribution to journalArticleAcademicpeer-review

29 Citations (Scopus)
2013

An ECVAG inter-laboratory validation study of the comet assay: inter-laboratory and intra-laboratory variations of DNA strand breaks and FPG-sensitive sites in human mononuclear cells.

Ersson, C., Moller, P., Forchhammer, L., Loft, S., Azqueta, A., Godschalk, R. W. L., van Schooten, F. J., Jones, G. D., Higgins, J. A., Cooke, M. S., Mistry, V., Karbaschi, M., Phillips, D. H., Sozeri, O., Routledge, M. N., Smith, K., Riso, P., Porrini, M., Matullo, G., Allione, A. & 10 others, Stepnik, M., Ferlinska, M., Teixeira, J. P., Costa, S., Corcuera, L. A., Lopez de Cerain, A., Laffon, B., Valdiglesias, V., Collins, A. R. & Moller, L., May 2013, In : Mutagenesis. 28, 3, p. 279-286 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Scopus)

Aromatic DNA adducts and number of lung cancer risk alleles in Map-Ta-Phut Industrial Estate workers and nearby residents.

Peluso, M., Srivatanakul, P., Jedpiyawongse, A., Sangrajrang, S., Munnia, A., Piro, S., Ceppi, M., Boffetta, P., Godschalk, R. W. L. & van Schooten, F. J., 1 Jan 2013, In : Mutagenesis. 28, 1, p. 57-63 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)