Roel L.H. Spätjens

Research activity per year

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Dive into the research topics where Roel L.H. Spätjens is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Dominant-Negative Control of cAMP-Dependent I-Ks Upregulation in Human Long-QT Syndrome Type 1
Heijman, J., Spätjens, R. L. H., Seyen, S. R. M., Lentink, V., Kuijpers, H. J. H., Boulet, I. R., de Windt, L. J., David, M. & Volders, P. G. A., 20 Jan 2012, In: Circulation Research. 110, 2, p. 211–219 9 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of I-Ks, but preserved cAMP-dependent up-regulation
Spätjens, R. L. H., Bebarova, M., Seyen, S. R. M., Lentink, V., Jongbloed, R. J., Arens, Y. H. J. M., Heijman, J. & Volders, P. G. A., 1 Oct 2014, In: Cardiovascular Research. 104, 1, p. 216-225 10 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
Probing the contribution of I-Ks to canine ventricular repolarization - Key role for beta-adrenergic receptor stimulation
Volders, P., Stengl, M., van Opstal, J., Gerlach, U., Spätjens, R. L. H., Beekman, J. D. M., Sipido, K. R. & Vos, M., 3 Jun 2003, In: Circulation. 107, 21, p. 2753-2760
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
Mutation location and I _Ksregulation in the arrhythmic risk of long QT syndrome type 1: the importance of the KCNQ1 S6 region
Schwartz, P. J., Moreno, C., Kotta, M.-C., Pedrazzini, M., Crotti, L., Dagradi, F., Castelletti, S., Haugaa, K. H., Denjoy, I., Shkolnikova, M. A., Brink, P. A., Heradien, M. J., Seyen, S. R. M., Spätjens, R. L. H., Spazzolini, C. & Volders, P. G. A., 7 Dec 2021, In: European Heart Journal. 42, 46, p. 4743-4755 13 p.
Research output: Contribution to journal › Article › Academic › peer-review

Open Access
Dipeptidyl aminopeptidase-like protein 6 regulates the INa-Ito balance influencing cardiac electrophysiology and arrhythmogenesis
Rossetti, A., Stoks, J., Spätjens, R. L. H. M. G., Kämmerer, S., Bayer, J., Li, X., Kosmidis, G., Firneburg, R., Seyen, S. R. M., Ter Bekke, R. M. A., Helderman-van den Enden, A. T. J. M., van Tintelen, J. P., Wilde, A. A. M., Loeys, B., Saenen, J., Heijman, J. & Volders, P. G. A., 29 Apr 2026, In: Science translational medicine. 18, 847, eadn3180.
Research output: Contribution to journal › Article › Academic › peer-review

UM Award 2014
Spätjens, R. (Recipient), 5 Jan 2015
Prize: Other distinction › Academic

2 Organizing or contributing to an event
2 External Collaborating in research projects
1 Attending an event

Masaryk University
Spätjens, R. (Visiting researcher)
15 May 2019 → 16 May 2019
Activity: External Collaboration / Teaching / Employment › External Collaborating in research projects › Academic
Meeting of the European Working Group on Cardiac Cellular Electrophysiology
ter Bekke, R. (Organiser), Moreno Vadillo, C. (Organiser), Schotten, U. (Organiser), Spätjens, R. (Organiser) & Volders, P. (Organiser)
20 Sept 2014 → 22 Sept 2014
Activity: Organizing, contributing or attending an event › Organizing or contributing to an event › Academic
EHRA EUROPACE 2013
Spätjens, R. (Participant / Attendee)
23 Jun 2013 → 26 Jun 2013
Activity: Organizing, contributing or attending an event › Attending an event › Academic
Heart Rhythm Society Scientific Sessions
Spätjens, R. (Participant / Attendee)
4 May 2011 → 7 May 2011
Activity: Organizing, contributing or attending an event › Organizing or contributing to an event › Academic
Columbia University, Department of Pharmacology
Spätjens, R. (Visiting researcher)
31 Jan 2008 → 7 Feb 2008
Activity: External Collaboration / Teaching / Employment › External Collaborating in research projects › Professional

Roel L.H. Spätjens, BASc

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