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2019

Alzheimer disease biomarkers may aid in the prognosis of MCI cases initially reverted to normal

Vermunt, L., van Paasen, A. J. L., Teunissen, C. E., Scheltens, P., Visser, P. J., Tijms, B. M. & Alzheimer's Disease Neuroimaging Initiative, 4 Jun 2019, In : Neurology. 92, 23, p. E2699-E2705 7 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Alzheimer's Disease Composite Score: a Post-Hoc Analysis Using Data from the LipiDiDiet Trial in Prodromal Alzheimer's Disease

Hendrix, S. B., Soininen, H., van Hees, A. M. J., Ellison, N., Visser, P. J., Solomon, A., Attali, A., Blennow, K., Kivipelto, M. & Hartmann, T., Oct 2019, In : JPAD-Journal of prevention of alzheimers disease. 6, 4, p. 232-236 5 p.

Research output: Contribution to journalArticleAcademicpeer-review

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort

Stamate, D., Kim, M., Proitsi, P., Westwood, S., Baird, A., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Teunissen, C. E., Kate, M. T., Scheltens, P., Gabel, S., Meersmans, K., Blin, O., Richardson, J., De Roeck, E., Engelborghs, S., Sleegers, K. & 25 others, Bordet, R., Ramit, L., Kettunen, P., Tsolaki, M., Verhey, F., Alcolea, D., Lléo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frölich, L., Dobricic, V., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., 2019, In : Alzheimer's and Dementia: Translational Research and Clinical Interventions. 5, p. 933-938 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of amyloid pathology with memory performance and cognitive complaints in cognitively normal older adults: a monozygotic twin study

Konijnenberg, E., den Braber, A., ten Kate, M., Tomassen, J., Mulder, S. D., Yaqub, M., Teunissen, C. E., Lammertsma, A. A., van Berckel, B. N. M., Scheltens, P., Boomsma, D. & Visser, P. J., May 2019, In : Neurobiology of Aging. 77, p. 58-65 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

van Maurik, I. S., Vos, S. J., Bos, I., Bouwman, F. H., Teunissen, C. E., Scheltens, P., Barkhof, F., Frolich, L., Kornhuber, J., Wiftfang, J., Maier, W., Peters, O., ROther, E., Nobili, F., Frisoni, G. B., Spiru, L., Freund-Levi, Y., Wallin, A. K., Hampel, H., Soininen, H. & 20 others, Tsolaki, M., Verhey, F., Kloszewska, I., Mecocci, P., Vellas, B., Lovestone, S., Gailuzzi, S., Herukka, S-K., Santana, I., Baldeiras, I., de Mendonca, A., Silva, D., Chetelat, G., Egret, S., Palmqvist, S., Hansson, O., Visser, P. J., Berkhof, J., van der Flier, W. M. & Alzheimer's Disease Neuroimaging Initiative, Nov 2019, In : Lancet Neurology. 18, 11, p. 1034-1044 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

Bos, I., Vos, S., Verhey, F., Scheltens, P., Teunissen, C., Engelborghs, S., Sleegers, K., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Tsolaki, M., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Lleo, A., Johannsen, P., Freund-Levi, Y., Froelich, L. & 12 others, Vandenberghe, R., Westwood, S., Dobricic, V., Barkhof, F., Legido-Quigley, C., Bertram, L., Lovestone, S., Streffer, J., Andreasson, U., Blennow, K., Zetterberg, H. & Visser, P. J., May 2019, In : Alzheimer's & Dementia. 15, 5, p. 644-654 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

Shi, L., Westwood, S., Baird, A. L., Winchester, L., Dobricic, V., Kilpert, F., Hong, S., Franke, A., Hye, A., Ashton, N. J., Morgan, A. R., Bos, I., Vos, S. J. B., Buckley, N. J., ten Kate, M., Scheltens, P., Vandenberghe, R., Gabel, S., Meersmans, K., Engelborghs, S. & 33 others, De Roeck, E. E., Sleegers, K., Frisoni, G. B., Blin, O., Richardson, J. C., Bordet, R., Molinuevo, J. L., Rami, L., Wallin, A., Kettunen, P., Tsolaki, M., Verhey, F., Lleo, A., Alcolea, D., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Johannsen, P., Teunissen, C. E., Freund-Levi, Y., Froelich, L., Legido-Quigley, C., Barkhof, F., Blennow, K., Zetterberg, H., Baker, S., Morgan, B. P., Streffer, J., Visser, P. J., Bertram, L., Lovestone, S. & Nevado-Holgado, A. J., Nov 2019, In : Alzheimer's & Dementia. 15, 11, p. 1478-1488 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype

Vermunt, L., Sikkes, S. A. M., van den Hout, A., Handels, R., Bos, I., van der Flier, W. M., Kern, S., Ousset, P-J., Maruff, P., Skoog, I., Verhey, F. R. J., Freund-Levi, Y., Tsolaki, M., Wallin, A. K., Rikkert, M. O., Soininen, H., Spiru, L., Zetterberg, H., Blennow, K., Scheltens, P. & 34 others, Muniz-Terrera, G., Visser, P. J., Vellas, B., Reynish, E., Ousset, P. J., Andrieu, S., Burns, A., Pasquier, F., Frisoni, G., Salmon, E., Michel, J. P., Zekry, D. S., Boada, M., Dartigues, J. F., Olde-Rikkert, M. G. M., Rigaud, A. S., Winblad, B., Malick, A., Sinclair, A., Froelich, L., Scheltens, P., Ribera, C., Touchon, J., Robert, P., Salva, A., Waldemar, G., Bullock, R., Tsolaki, M., Rodriguez, G., Spiru, L., Alzheimer's Disease Neuroimaging Initiative, AIBL Res Grp, ICTUS Study Grp & DSA Study Grp, Jul 2019, In : Alzheimer's & Dementia. 15, 7, p. 888-898 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

Lleo, A., Alcolea, D., Martinez-Lage, P., Scheltens, P., Parnetti, L., Poirier, J., Simonsen, A. H., Verbeek, M. M., Rosa-Neto, P., Slot, R. E. R., Tainta, M., Izaguirre, A., Reijs, B. L. R., Farotti, L., Tsolaki, M., Vandenbergue, R., Freund-Levi, Y., Verhey, F. R. J., Clarimon, J., Fortea, J. & 8 others, Frolich, L., Santana, I., Luis Molinuevo, J., Lehmann, S., Visser, P. J., Teunissen, C. E., Zetterberg, H. & Blennow, K., Jun 2019, In : Alzheimer's & Dementia. 15, 6, p. 742-753 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Modeling grey matter atrophy as a function of time, aging or cognitive decline show different anatomical patterns in Alzheimer's disease

Dicks, E., Vermunt, L., van der Flier, W. M., Visser, P. J., Barkhof, F., Scheltens, P., Tijms, B. M. & Alzheimer's Disease Neuroimaging Initiative, 2019, In : NeuroImage: Clinical. 22, p. 1-12 12 p., 101786.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Plasma levels of soluble TREM2 and neurofilament light chain in TREM2 rare variant carriers

Ashton, N. J., Suarez-Calvet, M., Heslegrave, A., Hye, A., Razquin, C., Pastor, P., Sanchez-Valle, R., Molinuevo, J. L., Visser, P. J., Blennow, K., Hodges, A. K. & Zetterberg, H., 28 Nov 2019, In : Alzheimer's Research & Therapy. 11, 1, 7 p., 94.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

Kim, M., Snowden, S., Suvitaival, T., Ali, A., Merkler, D. J., Ahmad, T., Westwood, S., Baird, A., Proitsi, P., Nevado-Holgado, A., Hye, A., Bos, I., Vos, S., Vandenberghe, R., Teunissen, C., ten Kate, M., Scheltens, P., Gabel, S., Meersmans, K., Blin, O. & 31 others, Richardson, J., De Roeck, E., Sleegers, K., Bordet, R., Rami, L., Kettunen, P., Tsolaki, M., Verhey, F., Sala, I., Lleo, A., Peyratout, G., Tainta, M., Johannsen, P., Freund-Levi, Y., Frolich, L., Dobricic, V., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Popp, J., Martinez-Lage, P., Bertram, L., Barkhof, F., Ashton, N., Blennow, K., Zetterberg, H., Streffer, J., Visser, P. J., Lovestone, S. & Legido-Quigley, C., Jun 2019, In : Alzheimer's & Dementia. 15, 6, p. 817-827 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Retinal thickness as a potential biomarker in patients with amyloid-proven early- and late-onset Alzheimer's disease

Haan, J. D., van de Kreeke, J. A., Konijnenberg, E., Kate, M. T., Braber, A. D., Barkhof, F., van Berckel, B. N., Teunissen, C. E., Scheltens, P., Visser, P. J., Verbraak, F. D. & Bouwman, F. H., Dec 2019, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 463-471 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Subjective cognitive decline and rates of incident Alzheimer's disease and non-Alzheimer's disease dementia

Slot, R. E. R., Sikkes, S. A. M., Berkhof, J., Brodaty, H., Buckley, R., Cavedo, E., Dardiotis, E., Guillo-Benarous, F., Hampel, H., Kochan, N. A., Lista, S., Luck, T., Maruff, P., Molinuevo, J. L., Kornhuber, J., Reisberg, B., Riedel-Heller, S. G., Risacher, S. L., Roehr, S., Sachdev, P. S. & 15 others, Scarmeas, N., Scheltens, P., Shulman, M. B., Saykin, A. J., Verfaillie, S. C. J., Visser, P. J., Vos, S. J. B., Wagner, M., Wolfsgruber, S., Jessen, F., van der Flier, W. M., Alzheimer's Disease Neuroimaging Initiative, DESCRIPA Working Grp, Insight-PreAD Study Grp & SCD-I Working Grp, Mar 2019, In : Alzheimer's & Dementia. 15, 3, p. 465-476 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The association of vascular disorders with incident dementia in different age groups

Legdeur, N., van der Lee, S. J., de Wilde, M., van der Lei, J., Muller, M., Maier, A. B. & Visser, P. J., 17 May 2019, In : Alzheimer's Research & Therapy. 11, 8 p., 47.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Use of mild cognitive impairment and prodromal AD/MCI due to AD in clinical care: a European survey

Bertens, D., Vos, S., Kehoe, P., Wolf, H., Nobili, F., Mendonca, A., van Rossum, I., Hort, J., Luis Molinuevo, J., Heneka, M., Petersen, R., Scheltens, P. & Visser, P. J., 22 Aug 2019, In : Alzheimer's Research & Therapy. 11, 1, 12 p., 74.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Vascular risk factors are associated with longitudinal changes in cerebrospinal fluid tau markers and cognition in preclinical Alzheimer's disease

Bos, I., Vos, S. J. B., Schindler, S. E., Hassenstab, J., Xiong, C., Grant, E., Verhey, F., Morris, J. C., Visser, P. J. & Fagan, A. M., Sep 2019, In : Alzheimer's & Dementia. 15, 9, p. 1149-1159 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+Study

Legdeur, N., Visser, P. J., Woodworth, D. C., Muller, M., Fletcher, E., Maillard, P., Scheltens, P., DeCarli, C., Kawas, C. H. & Corrada, M. M., Sep 2019, In : Journal of the American Geriatrics Society. 67, 9, p. 1827-1834 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

2018

Age and the association of dementia-related pathology with trajectories of cognitive decline

Jansen, W. J., Wilson, R. S., Visser, P. J., Nag, S., Schneider, J. A., James, B. D., Leurgans, S. E., Capuano, A. W., Bennett, D. A. & Boyle, P. A., 1 Jan 2018, In : Neurobiology of Aging. 61, p. 138-145 8 p.

Research output: Contribution to journalArticleAcademicpeer-review

Age dependency of risk factors for cognitive decline

Legdeur, N., Heymans, M. W., Comijs, H. C., Huisman, M., Maier, A. B. & Visser, P. J., 20 Aug 2018, In : BMC Geriatrics. 18, 10 p., 187.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Amyloid-beta, Tau, and Cognition in Cognitively Normal Older Individuals: Examining the Necessity to Adjust for Biomarker Status in Normative Data

Bos, I., Vos, S. J. B., Jansen, W. J., Vandenberghe, R., Gabel, S., Estanga, A., Ecay-Torres, M., Tomassen, J., den Braber, A., Lleo, A., Sala, I., Wallin, A., Kettunen, P., Molinuevo, J. L., Rami, L., Chetelat, G., de la Sayette, V., Tsolaki, M., Freund-Levi, Y., Johannsen, P. & 5 others, Novak, G. P., Ramakers, I., Verhey, F. R., Visser, P. J. & Alzheimer's Disease Neuroimaging Initiative, 25 Jun 2018, In : Frontiers in Aging Neuroscience. 10, 11 p., 193.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Jansen, W. J., Ossenkoppele, R., Tijms, B. M., Fagan, A. M., Hansson, O., Klunk, W. E., van der Flier, W. M., Villemagne, V. L., Frisoni, G. B., Fleisher, A. S., Lleo, A., Mintun, M. A., Wallin, A., Engelborghs, S., Na, D. L., Chetelat, G., Molinuevo, J. L., Landau, S. M., Mattsson, N., Kornhuber, J. & 31 others, Sabri, O., Rowe, C. C., Parnetti, L., Popp, J., Fladby, T., Jagust, W. J., Aalten, P., Lee, D. Y., Vandenberghe, R., de Oliveira, C. R., Kapaki, E., Froelich, L., Ivanoiu, A., Gabryelewicz, T., Verbeek, M. M., Sanchez-Juan, P., Hildebrandt, H., Camus, V., Zboch, M., Brooks, D. J., Drzezga, A., Rinne, J. O., Newberg, A., de Mendonca, A., Sarazin, M., Rabinovici, G. D., Madsen, K., Kramberger, M. G., Verhey, F. R. J., Visser, P. J. & Amyloid Biomarker Study Grp, 1 Jan 2018, In : JAMA Psychiatry. 75, 1, p. 84-95 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Atrophy subtypes in prodromal Alzheimer's disease are associated with cognitive decline

ten Kate, M., Dicks, E., Visser, P. J., van der Flier, W. M., Teunissen, C. E., Barkhof, F., Scheltens, P., Tijms, B. M., Alzheimer's Disease Neuroimaging Initiative & Amsterdam Dementia Cohort, Dec 2018, In : Brain. 141, p. 3443-3456 14 p.

Research output: Contribution to journalArticleAcademicpeer-review

Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource

Perera, G., Pedersen, L., Ansel, D., Alexander, M., Arrighi, H. M., Avillach, P., Foskett, N., Gini, R., Gordon, M. F., Gungabissoon, U., Mayer, M-A., Novak, G., Rijnbeek, P., Trifiro, G., van der Lei, J., Visser, P. J. & Stewart, R., 1 Feb 2018, In : Alzheimer's & Dementia. 14, 2, p. 130-139 10 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Disease trajectories in behavioural variant frontotemporal dementia, primary psychiatric and other neurodegenerative disorders presenting with behavioural change

Reus, L. M., Vijverberg, E. G. B., Tijms, B. M., ten Kate, M., Gossink, F., Krudop, W. A., del Campo, M., Teunissen, C. E., Barkhof, F., van der Flier, W. M., Visser, P. J., Dols, A. & Al Pijnenburg, Y., 1 Sep 2018, In : Journal of Psychiatric Research. 104, p. 183-191 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

European Prevention of Alzheimer's Dementia Registry: Recruitment and prescreening approach for a longitudinal cohort and prevention trials

Vermunt, L., Veal, C. D., ter Meulen, L., Chrysostomou, C., van der Flier, W., Frisoni, G. B., Guessous, I., Kivipelto, M., Marizzoni, M., Martinez-Lage, P., Molinuevo, J., Porteous, D., Ritchie, K., Scheltens, P., Ousset, P-J., Ritchie, C. W., Luscan, G., Brookes, A. J. & Visser, P. J., 1 Jun 2018, In : Alzheimer's & Dementia. 14, 6, p. 837-842 6 p.

Research output: Contribution to journalArticleAcademicpeer-review

Gray Matter Network Disruptions and Regional Amyloid Beta in Cognitively Normal Adults

ten Kate, M., Visser, P. J., Bakardjian, H., Barkhof, F., Sikkes, S. A. M., van der Flier, W. M., Scheltens, P., Hampel, H., Habert, M-O., Dubois, B., Tijms, B. M. & Insight-PreAD Study Grp, 15 Mar 2018, In : Frontiers in Aging Neuroscience. 10, 11 p., 67.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

MRI predictors of amyloid pathology: results from the EMIF-AD Multimodal Biomarker Discovery study

ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., Richardson, J. C., Bordet, R., Wallin, A., Eckerstrom, C., Molinuevo, J. L., Engelborghs, S., Van Broeckhoven, C., Martinez-Lage, P., Popp, J., Tsolaki, M. & 17 others, Verhey, F. R. J., Baird, A. L., Legido-Quigley, C., Bertram, L., Dobricic, V., Zetterberg, H., Lovestone, S., Streffer, J., Bianchetti, S., Novak, G. P., Revillard, J., Gordon, M. F., Xie, Z., Wottschel, V., Frisoni, G., Visser, P. J. & Barkhof, F., 27 Sep 2018, In : Alzheimer's Research & Therapy. 10, 12 p., 100.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Plasma Protein Biomarkers for the Prediction of CSF Amyloid and Tau and [18F]-Flutemetamol PET Scan Result

Westwood, S., Baird, A. L., Hye, A., Ashton, N. J., Nevado-Holgado, A. J., Anand, S. N., Liu, B., Newby, D., Bazenet, C., Kiddle, S. J., Ward, M., Newton, B., Desai, K., Hehir, C. T., Zanette, M., Galimberti, D., Parnetti, L., Lleo, A., Baker, S., Narayan, V. A. & 5 others, van der Flier, W. M., Scheltens, P., Teunissen, C. E., Visser, P. J. & Lovestone, S., 11 Dec 2018, In : Frontiers in Aging Neuroscience. 10, 15 p., 409.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Pre-amyloid stage of Alzheimer's disease in cognitively normal individuals

Tijms, B. M., Vermunt, L., Zwan, M. D., van Harten, A. C., van der Flier, W. M., Teunissen, C. E., Scheltens, P., Visser, P. J. & Alzheimer's Disease Neuroimaging Initiative, 1 Sep 2018, In : Annals of Clinical and Translational Neurology. 5, 9, p. 1037-1047 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Prevalence of amyloid-beta pathology in distinct variants of primary progressive aphasia

Bergeron, D., Gorno-Tempini, M. L., Rabinovici, G. D., Santos-Santos, M. A., Seeley, W., Miller, B. L., Pijnenburg, Y., Keulen, M. A., Groot, C., van Berckel, B. N. M., van der Flier, W. M., Scheltens, P., Rohrer, J. D., Warren, J. D., Schott, J. M., Fox, N. C., Sanchez-Valle, R., Grau-Rivera, O., Gelpi, E., Seelaar, H. & 66 others, Papma, J. M., van Swieten, J. C., Hodges, J. R., Leyton, C. E., Piguet, O., Rogalski, E. J., Mesulam, M. M., Koric, L., Nora, K., Pariente, J., Dickerson, B., Mackenzie, I. R., Hsiung, G-Y. R., Belliard, S., Irwin, D. J., Wolk, D. A., Grossman, M., Jones, M., Harris, J., Mann, D., Snowden, J. S., Chrem-Mendez, P., Calandri, I. L., Amengual, A. A., Miguet-Alfonsi, C., Magnin, E., Magnani, G., Santangelo, R., Deramecourt, V., Pasquier, F., Mattsson, N., Nilsson, C., Hansson, O., Keith, J., Masellis, M., Black, S. E., Matias-Guiu, J. A., Cabrera-Martin, M-N., Paquet, C., Dumurgier, J., Teichmann, M., Sarazin, M., Bottlaender, M., Dubois, B., Rowe, C. C., Villemagne, V. L., Vandenberghe, R., Granadillo, E., Teng, E., Mendez, M., Meyer, P. T., Frings, L., Lleo, A., Blesa, R., Fortea, J., Seo, S. W., Diehl-Schmid, J., Grimmer, T., Frederiksen, K. S., Sanchez-Juan, P., Chetelat, G., Jansen, W., Bouchard, R. W., Laforce, R. J., Visser, P. J. & Ossenkoppele, R., Nov 2018, In : Annals of Neurology. 84, 5, p. 729-740 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Prevalence of the apolipoprotein E epsilon 4 allele in amyloid beta positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., Frisoni, G. B., Ivanoiu, A., Chetelat, G., Oliveira, C. R., Rodrigue, K. M., Kornhuber, J., Wallin, A., Klimkowicz-Mrowiec, A., Kandimalla, R., Popp, J. & 75 others, Aalten, P. P., Aarsland, D., Alcolea, D., Almdahl, I. S., Baldeiras, I., Buchem, M. A., Cavedo, E., Chen, K., Cohen, A. D., Foerster, S., Fortea, J., Frederiksen, K. S., Freund-Levi, Y., Gill, K. D., Gkatzima, O., Grimmer, T., Hampel, H., Herukka, S-K., Johannsen, P., Laere, K., Leon, M. J., Maier, W., Marcusson, J., Meulenbroek, O., Mollergard, H. M., Morris, J. C., Mroczko, B., Nordlund, A., Prabhakar, S., Peters, O., Rami, L., Rodriguez-Rodriguez, E., Roe, C. M., Ruther, E., Santana, I., Schroder, J., Seo, S. W., Soininen, H., Spiru, L., Stomrud, E., Struyfs, H., Teunissen, C. E., Verhey, F. R. J., Vos, S. J. B., Doorn, L. J. C. V. W., Waldemar, G., Wallin, A. K., Wiltfang, J., Vandenberghe, R., Brooks, D. J., Fladby, T., Rowe, C. C., Drzezga, A., Verbeek, M. M., Sarazin, M., Wolk, D. A., Fleisher, A. S., Klunk, W. E., Na, D. L., Sanchez-Juan, P., Lee, D. Y., Nordberg, A., Tsolaki, M., Camus, V., Rinne, J. O., Fagan, A. M., Zetterberg, H., Blennow, K., Rabinovici, G. D., Hansson, O., Berckel, B. N. M., Flier, W. M., Scheltens, P., Visser, P. J. & Ossenkoppele, R., 1 Jul 2018, In : Alzheimer's & Dementia. 14, 7, p. 913-924 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Resilience to cognitive impairment in the oldest-old: design of the EMIF-AD 90+study

Legdeur, N., Badissi, M., Carter, S. F., de Crom, S., van de Kreeke, A., Vreeswijk, R., Trappenburg, M. C., Oudega, M. L., Koek, H. L., van Campen, J. P., Keijsers, C. J. P. W., Amadi, C., Hinz, R., Gordon, M. F., Novak, G., Podhorna, J., Serne, E., Verbraak, F., Yaqub, M., Hillebrand, A. & 12 others, Griffa, A., Pendleton, N., Kramer, S. E., Teunissen, C. E., Lammertsma, A., Barkhof, F., van Berckel, B. N. M., Scheltens, P., Muller, M., Maier, A. B., Herholz, K. & Visser, P. J., 26 Nov 2018, In : BMC Geriatrics. 18, 16 p., 289.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The EMIF-AD Multimodal Biomarker Discovery study: design, methods and cohort characteristics

Bos, I., Vos, S., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G., Molinuevo, J., Wallin, A., Lleo, A., Popp, J., Martinez-Lage, P., Baird, A., Dobson, R., Legido-Quigley, C., Sleegers, K., Van Broeckhoven, C., Bertram, L., ten Kate, M., Barkhof, F., Zetterberg, H. & 3 others, Lovestone, S., Streffer, J. & Visser, P. J., 6 Jul 2018, In : Alzheimer's Research & Therapy. 10, 9 p., 64.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The EMIF-AD PreclinAD study: study design and baseline cohort overview

Konijnenberg, E., Carter, S. F., ten Kate, M., den Braber, A., Tomassen, J., Amadi, C., Wesselman, L., Nguyen, H-T., van de Kreeke, J. A., Yaqub, M., Demuru, M., Mulder, S. D., Hillebrand, A., Bouwman, F. H., Teunissen, C. E., Serne, E. H., Moll, A. C., Verbraak, F. D., Hinz, R., Pendleton, N. & 7 others, Lammertsma, A. A., van Berckel, B. N. M., Barkhof, F., Boomsma, D., Scheltens, P., Herholz, K. & Visser, P. J., 4 Aug 2018, In : Alzheimer's Research & Therapy. 10, 12 p., 75.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Unbiased Approach to Counteract Upward Drift in Cerebrospinal Fluid Amyloid-beta 1-42 Analysis Results

Tijms, B. M., Willemse, E. A. J., Zwan, M. D., Mulder, S. D., Visser, P. J., van Berckel, B. N. M., van der Flier, W. M., Scheltens, P. & Teunissen, C. E., 1 Mar 2018, In : Clinical Chemistry. 64, 3, p. 576-585 10 p.

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White matter hyperintensities and vascular risk factors in monozygotic twins

ten Kate, M., Sudre, C. H., den Braber, A., Konijnenberg, E., Nivard, M. G., Cardoso, M. J., Scheltens, P., Ourselin, S., Boomsma, D. I., Barkhof, F. & Visser, P. J., 1 Jun 2018, In : Neurobiology of Aging. 66, p. 40-48 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet): a randomised, double-blind, controlled trial

Soininen, H., Solomon, A., Visser, P. J., Hendrix, S. B., Blennow, K., Kivipelto, M., Hartmann, T. & LipiDiDiet Clinical Study Grp, Dec 2017, In : Lancet Neurology. 16, 12, p. 965-975 11 p.

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Open Access

Amyloid-independent atrophy patterns predict time to progression to dementia in mild cognitive impairment

ten Kate, M., Barkhof, F., Visser, P. J., Teunissen, C. E., Scheltens, P., van der Flier, W. M. & Tijms, B. M., 12 Sep 2017, In : Alzheimer's Research & Therapy. 9, 8 p., 73.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Association Between Later Life Lifestyle Factors and Alzheimer's Disease Biomarkers in Non-Demented Individuals: A Longitudinal Descriptive Cohort Study

Reijs, B. L. R., Vos, S. J. B., Soininen, H., Lotjonen, J., Koikkalainen, J., Pikkarainen, M., Hall, A., Vanninen, R., Liu, Y., Herukka, S-K., Freund-Levi, Y., Frisoni, G. B., Frolich, L., Nobilij, F., Rikkert, M. O., Spiru, L., Tsolaki, M., Wallinn, A. K., Scheltens, P., Verhey, F. & 1 others, Visser, P. J., 2017, In : Journal of Alzheimer's Disease. 60, 4, p. 1387-1395 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 29 Dec 2017, In : Alzheimer's Research & Therapy. 9, 10 p., 101.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Clinical validity of medial temporal atrophy as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework

ten Kate, M., Barkhof, F., Boccardi, M., Visser, P. J., Jack, C. R., Lovblad, K-O., Frisoni, G. B., Scheltens, P. & Geneva Task Force Roadmap Alzhei, Apr 2017, In : Neurobiology of Aging. 52, p. 167-182 16 p.

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Cost-Utility of Using Alzheimer's Disease Biomarkers in Cerebrospinal Fluid to Predict Progression from Mild Cognitive Impairment to Dementia

Handels, R. L. H., Wimo, A., Dodel, R., Kramberger, M. G., Visser, P. J., Luis Molinuevo, J., Verhey, F. R. J. & Winblad, B., 7 Nov 2017, In : Journal of Alzheimer's Disease. 60, 4, p. 1477-1487 11 p.

Research output: Contribution to journalArticleAcademicpeer-review

Current Approaches and Clinician Attitudes to the Use of Cerebrospinal Fluid Biomarkers in Diagnostic Evaluation of Dementia in Europe

Miller, A-M., Balasa, M., Blennow, K., Gardiner, M., Rutkowska, A., Scheltens, P., Teunissen, C. E., Visser, P. J., Winblad, B., Waldemar, G. & Lawlor, B., 2017, In : Journal of Alzheimer's Disease. 60, 1, p. 201-210 10 p.

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Early-Onset Dementia Frequency, Diagnostic Procedures, and Quality Indicators in Three European Tertiary Referral Centers

Konijnenberg, E., Fereshtehnejad, S-M., ten Kate, M., Eriksdotter, M., Scheltens, P., Johannsen, P., Waldemar, G. & Visser, P. J., 2017, In : Alzheimer Disease & Associated Disorders. 31, 2, p. 146-151 6 p.

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Improved Cerebrospinal Fluid-Based Discrimination between Alzheimer's Disease Patients and Controls after Correction for Ventricular Volumes

van Doorn, L. J. C. V. W., Gispert, J. D., Kuiperij, H. B., Claassen, J. A. H. R., Arighi, A., Baldeiras, I., Blennow, K., Bozzali, M., Castelo-Branco, M., Cavedo, E., Emek-Savas, D. D., Eren, E., Eusebi, P., Farotti, L., Fenoglio, C., Ormaechea, J. F., Freund-Levi, Y., Frisoni, G. B., Galimberti, D., Genc, S. & 31 others, Greco, V., Hampel, H., Herukka, S-K., Liu, Y., Llado, A., Lleo, A., Nobili, F. M., Oguz, K. K., Parnetti, L., Pereira, J., Picco, A., Pikkarainen, M., de Oliveira, C. R., Saka, E., Salvadori, N., Sanchez-Valle, R., Santana, I., Scarpini, E., Scheltens, P., Soininen, H., Tarducci, R., Teunissen, C., Tsolaki, M., Urbani, A., Vilaplana, E., Visser, P. J., Wallin, A. K., Yener, G., Molinuevo, J. L., Meulenbroek, O. & Verbeek, M. M., 2017, In : Journal of Alzheimer's Disease. 56, 2, p. 543-555 13 p.

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Low Normal Cerebrospinal Fluid A-beta-42 Levels Predict Clinical Progression in Nondemented Subjects

Tijms, B. M., Bertens, D., Slot, R. E., Gouw, A. A., Teunissen, C. E., Scheltens, P., van der Flier, W. M. & Visser, P. J., May 2017, In : Annals of Neurology. 81, 5, p. 749-753 5 p.

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Memory Correlates of Alzheimer's Disease Cerebrospinal Fluid Markers: A Longitudinal Cohort Study

Reijs, B. L. R., Ramakers, I. H. G. B., Kohler, S., Teunissen, C. E., Koel-Simmelink, M., Nathan, P. J., Tsolaki, M., Wahlund, L-O., Waldemar, G., Hausner, L., Vandenberghe, R., Johannsen, P., Blackwell, A., Vanderstichele, H., Verhey, F. & Visser, P. J., 2017, In : Journal of Alzheimer's Disease. 60, 3, p. 1119-1128 10 p.

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Modifiable Risk Factors for Prevention of Dementia in Midlife, Late Life and the Oldest-Old: Validation of the LIBRA Index

Vos, S. J. B., van Boxtel, M. P. J., Schiepers, O. J. G., Deckers, K., de Vugt, M., Carriere, I., Dartigues, J-F., Peres, K., Artero, S., Ritchie, K., Galluzzo, L., Scafato, E., Frison, G. B., Huisman, M., Comijs, H. C., Sacuiu, S. F., Skoog, I., Irving, K., O'Donnell, C. A., Verhey, F. R. J. & 2 others, Visser, P. J. & Köhler, S., 2017, In : Journal of Alzheimer's Disease. 58, 2, p. 537-547 11 p.

Research output: Contribution to journalArticleAcademicpeer-review