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Research Output 2010 2019

  • 22 Article
  • 2 Review article
  • 1 Erratum / corrigendum
2019

Autoimmunity in psychotic disorders. Where we stand, challenges and opportunities

Mane-Damas, M., Hoffmann, C., Zong, S., Tan, A., Molenaar, P. C., Losen, M. & Martinez-Martinez, P., Sep 2019, In : Autoimmunity Reviews. 18, 9, p. 1-14 14 p., 102348.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access

Characterization of the thymus in Lrp4 myasthenia gravis: Four cases

Koneczny, I., Rennspiess, D., Marcuse, F., Dankerlui, N., Hamid, M. A., Mane-Damas, M., Maessen, J., Van Schil, P., Saxena, A., Zisimopoulou, P., Lazaridis, K., Woodhall, M., Karagiorgou, K., Tzartos, J., Tzartos, S., De Baets, M. H., Molenaar, P. C., Marx, A., zur Hausen, A., Losen, M. & 1 others, Martinez-Martinez, P., Jan 2019, In : Autoimmunity Reviews. 18, 1, p. 50-55 6 p.

Research output: Contribution to journalReview articleAcademicpeer-review

Open Access
2018

Addendum: Hoffmann, C.; et al. Autoantibodies in Neuropsychiatric Disorders. Antibodies 2016, 5, 9

Sep 2018, In : ANTIBODIES. 7, 3, 1 p., 33.

Research output: Contribution to journalErratum / corrigendumAcademic

Open Access

Alpha7 acetylcholine receptor autoantibodies are rare in sera of patients diagnosed with schizophrenia or bipolar disorder

Hoffmann, C., Stevens, J., Zong, S., van Kruining, D., Saxena, A., Kucukali, C. I., Tuzun, E., Yalcinkaya, N., De Hert, M., Gonzalez-Vioque, E., Arango, C., Lindstrom, J., De Beets, M. H., Rutter, B. P. F., van Os, J., Molenaar, P., Losen, M. & Martinez-Martinez, P., 6 Dec 2018, In : PLOS ONE. 13, 12, 12 p., e0208412.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
2017

Characterization of an anti-fetal AChR monoclonal antibody isolated from a myasthenia gravis patient

Saxena, A., Stevens, J., Cetin, H., Koneczny, I., Webster, R., Lazaridis, K., Tzartos, S., Vrolix, K., Nogales-Gadea, G., Machiels, B., Molenaar, P. C., Damoiseaux, J., De Baets, M. H., Simon-Keller, K., Marx, A., Vincent, A., Losen, M. & Martinez-Martinez, P., 31 Oct 2017, In : Scientific Reports. 7, 12 p., 14426.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Hinge-deleted IgG4 blocker therapy for acetylcholine receptor myasthenia gravis in rhesus monkeys

Losen, M., Labrijn, A. F., van Kranen-Mastenbroek, V. H., Janmaat, M. L., Haanstra, K. G., Beurskens, F. J., Vink, T., Jonker, M., 't Hart, B. A., Mane-Damas, M., Molenaar, P. C., Martinez-Martinez, P., van der Esch, E., Schuurman, J., de Baets, M. H. & Parren, P. W. H. I., 20 Apr 2017, In : Scientific Reports. 7, 11 p., 992.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

IgG4 autoantibodies against muscle-specific kinase undergo Fab-arm exchange in myasthenia gravis patients

Koneczny, I., Stevens, J. A. A., De Rosa, A., Huda, S., Huijbers, M. G., Saxena, A., Maestri, M., Lazaridis, K., Zisimopoulou, P., Tzartos, S., Verschuuren, J., van der Maarel, S. M., van Damme, P., De Baets, M. H., Molenaar, P. C., Vincent, A., Ricciardi, R., Martinez-Martinez, P. & Losen, M., Feb 2017, In : Journal of Autoimmunity. 77, p. 104-115 12 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
Open Access
2016

Autoantibodies in Neuropsychiatric Disorders

Hoffmann, C., Zong, S., Mane-Damas, M., Molenaar, P., Losen, M. & Martinez-Martinez, P., Jun 2016, In : ANTIBODIES. 5, 2, 9.

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

Silencing of Dok-7 in Adult Rat Muscle Increases Susceptibility to Passive Transfer Myasthenia Gravis

Gomez, A. M., Stevens, J. A. A., Mane-Damas, M., Molenaar, P., Duimel, H., Verheyen, F., Cossins, J., Beeson, D., De Baets, M. H., Losen, M. & Martinez-Martinez, P., Oct 2016, In : American Journal of Pathology. 186, 10, p. 2559-2568

Research output: Contribution to journalArticleAcademicpeer-review

2015

Auto-immuunaandoeningen als mogelijke oorzaak van neuropsychiatrische syndromen

Martinez Martinez, P., Molenaar, P., Losen, M., Hoffmann, C., Stevens, J., de Witte, L. D., van Amelsvoort, T., van Os, J. & Rutten, B., 2015, In : Tijdschrift voor Psychiatrie.

Research output: Contribution to journalArticleAcademicpeer-review

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells

Nogales-Gadea, G., Saxena, A., Hoffmann, C., Hounjet, J., Coenen, D., Molenaar, P., Losen, M. & Martinez-Martinez, P., Jun 2015, In : Journal of visualized experiment. 100, e52830.

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Standardization of the experimental autoimmune myasthenia gravis (EAMG) model by immunization of rats with Torpedo californica acetylcholine receptors - Recommendations for methods and experimental designs

Losen, M., Martinez-Martinez, P., Molenaar, P. C., Lazaridis, K., Tzartos, S., Brenner, T., Duan, R-S., Luo, J., Lindstrom, J. & Kusner, L., Aug 2015, In : Experimental Neurology. 270, p. 18-28

Research output: Contribution to journalArticleAcademicpeer-review

2014
13 Citations (Scopus)

Clonal heterogeneity of thymic B cells from early-onset myasthenia gravis patients with antibodies against the acetylcholine receptor

Vrolix, K., Fraussen, J., Losen, M., Stevens, J., Lazaridis, K., Molenaar, P. C., Somers, V., Alma Bracho, M., Le Panse, R., Stinissen, P., Berrih-Aknin, S., Maessen, J. G., Van Garsse, L., Buurman, W. A., Tzartos, S. J., De Baets, M. H. & Martinez-Martinez, P., Aug 2014, In : Journal of Autoimmunity. 52, p. 101-112

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Complement Activation by Ceramide Transporter Proteins

Bode, G. H., Losen, M., Buurman, W. A., Veerhuis, R., Molenaar, P. C., Steinbusch, H. W. M., De Baets, M. H., Daha, M. R. & Martinez-Martinez, P., 1 Feb 2014, In : Journal of Immunology. 192, 3, p. 1154-1161

Research output: Contribution to journalArticleAcademicpeer-review

Glycine receptor antibodies in PERM: a new channelopathy

Martinez-Martinez, P., Molenaar, P. C., Losen, M. & de Baets, M. H., Aug 2014, In : Brain. 137, p. 2115-2116

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Proteasome Inhibition with Bortezomib Depletes Plasma Cells and Specific Autoantibody Production in Primary Thymic Cell Cultures from Early-Onset Myasthenia Gravis Patients

Gomez, A. M., Willcox, N., Vrolix, K., Hummel, J., Nogales-Gadea, G., Saxena, A., Duimel, H., Verheyen, F., Molenaar, P. C., Buurman, W. A., De Baets, M. H., Martinez-Martinez, P. & Losen, M., 1 Aug 2014, In : Journal of Immunology. 193, 3, p. 1055-1063

Research output: Contribution to journalArticleAcademicpeer-review

2013

Pathophysiology of myasthenia gravis with antibodies to the acetylcholine receptor, muscle-specific kinase and low-density lipoprotein receptor-related protein 4

Verschuuren, J. J. G. M., Huijbers, M. G., Plomp, J. J., Niks, E. H., Molenaar, P. C., Martinez-Martinez, P., Gomez, A. M., De Baets, M. H. & Losen, M., Jul 2013, In : Autoimmunity Reviews. 12, 9, p. 918-923

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Proteomic analysis of rat tibialis anterior muscles at different stages of experimental autoimmune myasthenia gravis

Gomez, A. M., Vanheel, A., Losen, M., Molenaar, P. C., De Baets, M. H., Noben, J-P., Hellings, N. & Martinez-Martinez, P., 15 Aug 2013, In : Journal of Neuroimmunology. 261, 1-2, p. 141-145

Research output: Contribution to journalArticleAcademicpeer-review

2012
13 Citations (Scopus)

Goodpasture Antigen-binding Protein/Ceramide Transporter Binds to Human Serum Amyloid P-Component and Is Present in Brain Amyloid Plaques

Mencarelli, C., Bode, G. H., Losen, M., Kulharia, M., Molenaar, P. C., Veerhuis, R., Steinbusch, H. W. M., De Baets, M. H., Nicolaes, G. A. F. & Martinez-Martinez, P., 27 Apr 2012, In : Journal of Biological Chemistry. 287, 18, p. 14897-14911

Research output: Contribution to journalArticleAcademicpeer-review

Targeting plasma cells with proteasome inhibitors: possible roles in treating myasthenia gravis?

Gomez, A. M., Willcox, N., Molenaar, P. C., Buurman, W. A., Martinez-Martinez, P., De Baets, M. H. & Losen, M., 2012, In : Annals of the New York Academy of Sciences. 1274, p. 48-59

Research output: Contribution to journalArticleAcademicpeer-review

2011

Proteasome Inhibition with Bortezomib Depletes Plasma Cells and Autoantibodies in Experimental Autoimmune Myasthenia Gravis

Gomez, A. M., Vrolix, K., Martinez-Martinez, P., Molenaar, P. C., Phernambucq, M., van der Esch, E., Duimel, H., Verheyen, F., Voll, R. E., Manz, R. A., De Baets, M. H. & Losen, M., 15 Feb 2011, In : Journal of Immunology. 186, 4, p. 2503-2513

Research output: Contribution to journalArticleAcademicpeer-review

Reduced thymic expression of ErbB receptors without auto-antibodies against synaptic ErbB in myasthenia gravis

Vrolix, K., Niks, E. H., Le Panse, R., van Ostaijen-ten Dam, M. M., Muris, A-H., Jol-van der Zijde, C. M., van Tol, M. J. D., Losen, M., Molenaar, P. C., van Zoelen, E. J. J., Berrih-Aknin, S., De Baets, M. H., Verschuuren, J. J. G. M. & Martinez-Martinez, P., Mar 2011, In : Journal of Neuroimmunology. 232, 1-2, p. 158-165

Research output: Contribution to journalArticleAcademicpeer-review

2010

Antibody effector mechanisms in myasthenia gravis-Pathogenesis at the neuromuscular junction

Gomez, A. M., Van den Broeck, J., Vrolix, K., Janssen, S. P., Lemmens, M. A. M., van der Esch, E., Duimel, H., Frederik, P., Molenaar, P. C., Martinez-Martinez, P., De Baets, M. H. & Losen, M., 2010, In : Autoimmunity. 43, 5-6, p. 353-370

Research output: Contribution to journalArticleAcademicpeer-review

The auto-antigen repertoire in myasthenia gravis

Vrolix, K., Fraussen, J., Molenaar, P. C., Losen, M., Somers, V., Stinissen, P., De Baets, M. H. & Martinez-Martinez, P., 2010, In : Autoimmunity. 43, 5-6, p. 380-400

Research output: Contribution to journalArticleAcademicpeer-review