20022019

Research output per year

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Research Output

  • 63 Article
  • 3 Review article
  • 1 Erratum / corrigendum
  • 1 Doctoral Thesis
2002

Behavioral problems in dementia: a factor analysis of the neuropsychiatric inventory

Aalten, P., de Vugt, M. E., Lousberg, R., Korten, E., Jaspers, N., Senden, B., Jolles, J. & Verhey, F. R. J., 1 Jan 2002, In : Dementia and Geriatric Cognitive Disorders. 15; 2, p. 99-105

Research output: Contribution to journalArticleAcademicpeer-review

156 Citations (Scopus)
2003

Behavioural disturbances in dementia patients and quality of the marital relationship.

de Vugt, M. E., Stevens, F. C. J., Aalten, P., Lousberg, R., Jaspers, N., Winkens, I., Jolles, J. & Verhey, F. R. J., 1 Jan 2003, In : International Journal of Geriatric Psychiatry. 18, p. 149-54

Research output: Contribution to journalArticleAcademicpeer-review

99 Citations (Scopus)
2004

Behavioral problems in dementia : course and risk factors

Aalten, P., 1 Jan 2004, Maastricht: NeuroPsych Publishers. 175 p.

Research output: ThesisDoctoral ThesisInternal

Open Access
File
165 Downloads (Pure)

Do caregiver management strategies influence patient behaviour in dementia?

de Vugt, M. E., Stevens, F. C., Aalten, P., Lousberg, R., Jaspers, N., Winkens, I., Jolles, J. & Verhey, F. R. J., 1 Jan 2004, In : International Journal of Geriatric Psychiatry. 19, p. 85-92

Research output: Contribution to journalArticleAcademicpeer-review

94 Citations (Scopus)
2005

Behavioral problems in dementia patients and salivary cortisol patterns in caregivers.

de Vugt, M. E., Nicolson, N. A., Aalten, P., Lousberg, R., Jolles, J. & Verhey, F. R. J., 1 Jan 2005, In : Journal of Neuropsychiatry and Clinical Neurosciences. 17, p. 201-207

Research output: Contribution to journalArticleAcademicpeer-review

67 Citations (Scopus)

The course of neuropsychiatric symptoms in dementia Part I: findings from the two-year longitudinal Maasbed study.

Aalten, P., de Vugt, M. E., Jaspers, N., Jolles, J. & Verhey, F. R. J., 1 Jan 2005, In : International Journal of Geriatric Psychiatry. 20, p. 523-530

Research output: Contribution to journalArticleAcademicpeer-review

144 Citations (Scopus)
51 Citations (Scopus)
2006

Awareness and behavioral problems in dementia patients: a prospective study

Aalten, P., van Valen, E., de Vugt, M. E., Lousberg, R., Jolles, J. & Verhey, F. R. J., 1 Jan 2006, In : International Psychogeriatrics. 18, 1, p. 3-17

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
53 Citations (Scopus)
254 Downloads (Pure)

Cognitive functioning in spousal caregivers of dementia patients: findings from the prospective MAASBED study

de Vugt, M. E., Jolles, J., van Osch, L. A. D. M., Stevens, F. C. J., Aalten, P., Lousberg, R. & Verhey, F. R. J., 1 Jan 2006, In : Age and Ageing. 35, 2, p. 160-166

Research output: Contribution to journalArticleAcademicpeer-review

35 Citations (Scopus)
2007
23 Citations (Scopus)

The influence of neuropsychological functioning on neuropsychiatric problems in dementia

Aalten, P., Jolles, J., de Vugt, M. E. & Verhey, F. R. J., 1 Jan 2007, In : Journal of Neuropsychiatry and Clinical Neurosciences. 19, 1, p. 50-56

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)
2008

The association between APOE genotype and memory dysfunction in subjects with mild cognitive impairment is related to age and Alzheimer pathology

Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Bekers, O., Sleegers, K., van Broeckhoven, C. L., Jolles, J. & Verhey, F. R., 1 Jan 2008, In : Dementia and Geriatric Cognitive Disorders. 26, 2, p. 101-8

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
36 Citations (Scopus)
180 Downloads (Pure)
2010

Affective symptoms as predictors of Alzheimer's disease in subjects with mild cognitive impairment: a 10-year follow-up study

Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Kester, A., Jolles, J. & Verhey, F. R. J., Jul 2010, In : Psychological Medicine. 40, 7, p. 1193-1201

Research output: Contribution to journalArticleAcademicpeer-review

Neuroanatomical correlates of apathy in Parkinson's disease: A magnetic resonance imaging study using voxel-based morphometry

Reijnders, J. S. A. M., Scholtissen, B., Weber, W. E. J., Aalten, P., Verhey, F. R. J. & Leentjens, A. F. G., 1 Jan 2010, In : Movement Disorders. 14, p. 2318-2325

Research output: Contribution to journalArticleAcademicpeer-review

The Predictive Value of Memory Strategies for Alzheimer's Disease in Subjects with Mild Cognitive Impairment

Ramakers, I. H. G. B., Visser, P. J., Aalten, P., Maes, H. L., Lansdaal, H. G. M., Meijs, C. J. C., Jolles, J. & Verhey, F. R. J., Feb 2010, In : Archives of Clinical Neuropsychology. 25, 1, p. 71-77

Research output: Contribution to journalArticleAcademicpeer-review

2011

Atrophy in the parahippocampal gyrus as an early biomarker of Alzheimer's disease

Echavarri, C., Aalten, P., Uylings, H. B. M., Jacobs, H. I. L., Visser, P. J., Gronenschild, E. H. B. M., Verhey, F. R. J. & Burgmans, S., Jan 2011, In : Brain Structure & Function. 215, 3-4, p. 265-271

Research output: Contribution to journalArticleAcademicpeer-review

Neuropsychological correlates of apathy in mild cognitive impairment and Alzheimer's disease: the role of executive functioning

Drijgers, R. L., Verhey, F. R. J., Leentjens, A. F. G., Kohler, S. & Aalten, P., Oct 2011, In : International Psychogeriatrics. 23, 8, p. 1327-1333

Research output: Contribution to journalArticleAcademicpeer-review

2012

Diagnostic and economic evaluation of new biomarkers for Alzheimer's disease: the research protocol of a prospective cohort study

Handels, R. L. H., Aalten, P., Wolfs, C. A. G., OldeRikkert, M., Scheltens, P., Visser, P. J., Joore, M. A., Severens, J. L. & Verhey, F. R. J., 10 Aug 2012, In : BMC Neurology. 12

Research output: Contribution to journalArticleAcademicpeer-review

24 Citations (Scopus)
66 Citations (Scopus)

Prevalence of Neuropsychiatric Symptoms in Young-Onset Compared to Late-Onset Alzheimer's Disease - Part 1: Findings of the Two-Year Longitudinal NeedYD-Study

van Vliet, D., de Vugt, M. E., Aalten, P., Bakker, C., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., Koopmans, R. T. C. M. & Verhey, F. R. J., 2012, In : Dementia and Geriatric Cognitive Disorders. 34, 5-6, p. 319-327

Research output: Contribution to journalArticleAcademicpeer-review

Test sequence of CSF and MRI biomarkers for prediction of AD in subjects with MCI

Vos, S., van Rossum, I. A., Burns, L., Knol, D., Scheltens, P., Soininen, H., Wahlund, L-O., Hampel, H., Tsolaki, M., Minthon, L., Handels, R., L'Italien, G., van der Flier, W. M., Aalten, P., Teunissen, C., Barkhof, F., Blennow, K., Wolz, R., Rueckert, D., Verhey, F. & 1 others, Visser, P. J., Oct 2012, In : Neurobiology of Aging. 33, 10, p. 2272-2281

Research output: Contribution to journalArticleAcademicpeer-review

12 Citations (Scopus)
2013

Anxiety is related to Alzheimer cerebrospinal fluid markers in subjects with mild cognitive impairment

Ramakers, I. H. G. B., Verhey, F. R. J., Scheltens, P., Hampel, H., Soininen, H., Aalten, P., Rikkert, M. O., Verbeek, M. M., Spiru, L., Blennow, K., Trojanowski, J. Q., Shaw, L. M. & Visser, P. J., May 2013, In : Psychological Medicine. 43, 5, p. 911-920

Research output: Contribution to journalArticleAcademicpeer-review

27 Citations (Scopus)

Awareness and Its Association With Affective Symptoms in Young-onset and Late-onset Alzheimer Disease: A Prospective Study

van Vliet, D., de Vugt, M. E., Koehler, S., Aalten, P., Bakker, C., Pijnenburg, Y. A. L., Vernooij-Dassen, M. J. F. J., Koopmans, R. T. C. M. & Verhey, F. R. J., 2013, In : Alzheimer Disease & Associated Disorders. 27, 3, p. 265-271

Research output: Contribution to journalArticleAcademicpeer-review

Determinants of Care Costs of Patients With Dementia or Cognitive Impairment

Handels, R. L. H., Wolfs, C. A. G., Aalten, P., Verhey, F. R. J. & Severens, J. L., 2013, In : Alzheimer Disease & Associated Disorders. 27, 1, p. 30-36

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Impact of molecular imaging on the diagnostic process in a memory clinic

Ossenkoppele, R., Prins, N. D., Pijnenburg, Y. A. L., Lemstra, A. W., van der Flier, W. M., Adriaanse, S. F., Windhorst, A. D., Handels, R. L. H., Wolfs, C. A. G., Aalten, P., Verhey, F. R. J., Verbeek, M. M., van Buchem, M. A., Hoekstra, O. S., Lammertsma, A. A., Scheltens, P. & van Berckel, B. N. M., Jul 2013, In : Alzheimer's & Dementia. 9, 4, p. 414-421

Research output: Contribution to journalArticleAcademicpeer-review

63 Citations (Scopus)

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

Clerx, L., van Rossum, I. A., Burns, L., Knol, D. L., Scheltens, P., Verhey, F., Aalten, P., Lapuerta, P., van de Pol, L., van Schijndel, R., de Jong, R., Barkhof, F., Wolz, R., Rueckert, D., Bocchetta, M., Tsolaki, M., Nobili, F., Wahlund, L-O., Minthon, L., Froelich, L. & 3 others, Hampel, H., Soininen, H. & Visser, P. J., Aug 2013, In : Neurobiology of Aging. 34, 8, p. 2003-2013

Research output: Contribution to journalArticleAcademicpeer-review

31 Citations (Scopus)

Progression to dementia in memory clinic patients without dementia A latent profile analysis

Kohler, S., Hamel, R., Sistermans, N., Koene, T., Pijnenburg, Y. A. L., van der Flier, W. M., Scheltens, P., Visser, P-J., Aalten, P., Verhey, F. R. J. & Ramakers, I., 8 Oct 2013, In : Neurology. 81, 15, p. 1342-1349

Research output: Contribution to journalArticleAcademicpeer-review

Sensitivity of Different MRI-Techniques to Assess Gray Matter Atrophy Patterns in Alzheimer's Disease is Region-Specific

Clerx, L., Jacobs, H. I. L., Burgmans, S., Gronenschild, E. H. B. M., Uylings, H. B. M., Echavarri, C., Visser, P. J., Verhey, F. R. J. & Aalten, P., Nov 2013, In : Current Alzheimer Research. 10, 9, p. 940-951

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)
2014

A review of current information and communication technologies: can they be used to assess apathy?

Koenig, A., Aalten, P., Verhey, F., Bensadoun, G., Petit, P-D., Robert, P. & David, R., Apr 2014, In : International Journal of Geriatric Psychiatry. 29, 4, p. 345-358

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Diagnosing Alzheimer's disease: A systematic review of economic evaluations

Handels, R. L. H., Wolfs, C. A. G., Aalten, P., Joore, M., Verhey, F. R. J. & Severens, J. L., Mar 2014, In : Alzheimer's & Dementia. 10, 2, p. 225-237 13 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
File
108 Downloads (Pure)

Optimizing the use of expert panel reference diagnoses in diagnostic studies of multidimensional syndromes

Wolfs, C. A. G., Aalten, P., Bossuyt, P. M. M., Joore, M. A., Leentjens, A. F. G., Severens, J. L. & Verhey, F. R. J., 1 Jan 2014, In : BMC Neurology. 14, 190.

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

The Dutch Parelsnoer Institute - Neurodegenerative diseases; methods, design and baseline results

Aalten, P., Ramakers, I. H. G. B., Biessels, G. J., de Deyn, P. P., Koek, H. L., OldeRikkert, M. G. M., Oleksik, A. M., Richard, E., Smits, L. L., van Swieten, J. C., Teune, L. K., van der Lugt, A., Barkhof, F., Teunissen, C. E., Rozendaal, N., Verhey, F. R. J. & van der Flier, W. M., 31 Dec 2014, In : BMC Neurology. 14, 254.

Research output: Contribution to journalArticleAcademicpeer-review

8 Citations (Scopus)

The Influence of Co-Morbidity and Frailty on the Clinical Manifestation of Patients with Alzheimer's Disease

Oosterveld, S. M., Kessels, R. P. C., Hamel, R., Ramakers, I. H. G. B., Aalten, P., Verhey, F. R. J., Sistermans, N., Smits, L. L., Pijnenburg, Y. A., van der Flier, W. M., Rikkert, M. G. M. O. & Melis, R. J. F., 2014, In : Journal of Alzheimer's Disease. 42, 2, p. 501-509

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)

Variability of CSF Alzheimer's Disease Biomarkers: Implications for Clinical Practice

Vos, S. J. B., Visser, P. J., Verhey, F., Aalten, P., Knol, D., Ramakers, I., Scheltens, P., Rikkert, M. G. M. O., Verbeek, M. M. & Teunissen, C. E., 24 Jun 2014, In : PLOS ONE. 9, 6, e100784.

Research output: Contribution to journalArticleAcademicpeer-review

22 Citations (Scopus)

White Matter Hyperintensities are Positively Associated with Cortical Thickness in Alzheimer's Disease

Jacobs, H. I. L., Clerx, L., Gronenschild, E. H. B. M., Aalten, P. & Verhey, F. R. J., 2014, In : Journal of Alzheimer's Disease. 39, 2, p. 409-422

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)
2015

Can FreeSurfer Compete with Manual Volumetric Measurements in Alzheimer's Disease?

Clerx, L., Gronenschild, E. H. B. M., Echavarri, C., Verhey, F., Aalten, P. & Jacobs, H. I. L., 2015, In : Current Alzheimer Research. 12, 4, p. 358-367

Research output: Contribution to journalArticleAcademicpeer-review

Ecological assessment of autonomy in instrumental activities of daily living in dementia patients by the means of an automatic video monitoring system

Konig, A., Crispim-Junior, C. F., Covella, A. G. U., Bremond, F., Derreumaux, A., Bensadoun, G., David, R., Verhey, F., Aalten, P. & Robert, P., 2 Jun 2015, In : Frontiers in Aging Neuroscience. 7, 98.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
5 Citations (Scopus)

Neuropsychiatrische syndromen na een beroerte

Schievink, S., Douven, E., Aalten, P. & Köhler, S., 2015, In : Tijdschrift voor neuropsychiatrie en gedragsneurologie.

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)

The Role of Information and Communication Technologies in Clinical Trials with Patients with Alzheimer's Disease and Related Disorders

König, A., Sacco, G., Bensadoun, G., Bremond, F., David, R., Verhey, F., Aalten, P., Robert, P. & Manera, V., 2015, In : Frontiers in Aging Neuroscience. 7, p. 110

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)

The trajectory of cognitive decline in the pre-dementia phase in memory clinic visitors: findings from the 4C-MCI study

Hamel, R., Kohler, S., Sistermans, N., Koene, T., Pijnenburg, Y., van der Flier, W., Scheltens, P., Aalten, P., Verhey, F., Visser, P. J. & Ramakers, I., May 2015, In : Psychological Medicine. 45, 7, p. 1509-1519

Research output: Contribution to journalArticleAcademicpeer-review

5 Citations (Scopus)

Validation of an Automatic Video Monitoring System for the Detection of Instrumental Activities of Daily Living in Dementia Patients

Konig, A., Crispim, C. F. J., Derreumaux, A., Bensadoun, G., Petit, P-D., Bremond, F., David, R., Verhey, F., Aalten, P. & Robert, P., 2015, In : Journal of Alzheimer's Disease. 44, 2, p. 675-685

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)
2016

Added Prognostic Value of Cerebrospinal Fluid Biomarkers in Predicting Decline in Memory Clinic Patients in a Prospective Cohort

Handels, R. L. H., Joore, M. A., Vos, S. J. B., Aalten, P., Ramakers, I. H. G. B., Rikkert, M. O., Scheltens, P., Jansen, W. J., Visser, P-J., van Berckel, B. M. N., van Domburg, P., Smid, M., Hoff, E., Hoogmoed, J., Bouwman, F., Claassen, J., Leentjens, A. F. G., Wolfs, C. A. G., Severens, J. L. & Verhey, F. R. J., 2016, In : Journal of Alzheimer's Disease. 52, 3, p. 875-885

Research output: Contribution to journalArticleAcademicpeer-review

1 Citation (Scopus)

A profile of The Clinical Course of Cognition and Comorbidity in Mild Cognitive Impairment and Dementia Study (The 4C study): two complementary longitudinal, clinical cohorts in the Netherlands

Liao, W., Hamel, R. E. G., Rikkert, M. G. M. O., Oosterveld, S. M., Aalten, P., Verhey, F. R. J., Scheltens, P., Sistermans, N., Pijnenburg, Y. A. L., van der Flier, W. M., Ramakers, I. H. G. B. & Melis, R. J. F., 25 Nov 2016, In : BMC Neurology. 16, 242.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design

Douven, E., Schievink, S. H. J., Verhey, F. R. J., van Oostenbrugge, R. J., Aalten, P., Staals, J. & Köhler, S., 12 May 2016, In : BMC Neurology. 16, 65.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access
1 Citation (Scopus)
2017

Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

Bos, I., Verhey, F. R., Ramakers, I. H. G. B., Jacobs, H. I. L., Soininen, H., Freund-Levi, Y., Hampel, H., Tsolaki, M., Wallin, A. K., van Buchem, M. A., Oleksik, A., Verbeek, M. M., Rikkert, M. O., van der Flier, W. M., Scheltens, P., Aalten, P., Visser, P. J. & Vos, S. J. B., 29 Dec 2017, In : Alzheimer's Research & Therapy. 9, 10 p., 101.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Diagnostic impact of [18F]flutemetamol PET in early-onset dementia

Zwan, M. D., Bouwman, F. H., Konijnenberg, E., van der Flier, W. M., Lammertsma, A. A., Verhey, F. R. J., Aalten, P., van Berckel, B. N. M. & Scheltens, P., 17 Jan 2017, In : Alzheimer's Research & Therapy. 9, 8 p., 2.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access

Gait Speed and Grip Strength Reflect Cognitive Impairment and Are Modestly Related to Incident Cognitive Decline in Memory Clinic Patients With Subjective Cognitive Decline and Mild Cognitive Impairment: Findings From the 4C Study

Hooghiemstra, A. M., Ramakers, I. H. G. B., Sistermans, N., Pijnenburg, Y. A. L., Aalten, P., Hamel, R. E. G., Melis, R. J. F., Verhey, F. R. J., Rikkert, M. G. M. O., Scheltens, P. & van der Flier, W. M., Jun 2017, In : Journals of Gerontology Series A-Biological Sciences and Medical Sciences. 72, 6, p. 846-854 9 p.

Research output: Contribution to journalArticleAcademicpeer-review

Open Access